ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	78/469	175/18639	0.445714285714286	17.7135790435577	3.21204624693454e-78	2.11995052297679e-75
GO:0019843	rRNA binding	20/469	65/18639	0.307692307692308	12.2283090044284	6.90804614785681e-17	2.27965522879275e-14
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	20/469	68/18639	0.294117647058824	11.6888247836448	1.8668989462652e-16	4.10717768178344e-14
GO:0015078	proton transmembrane transporter activity	28/469	185/18639	0.151351351351351	6.01500605082695	2.25797391426887e-14	3.72565695854364e-12
GO:0009055	electron transfer activity	22/469	116/18639	0.189655172413793	7.53727667083303	1.25720726120552e-13	1.65951358479129e-11
GO:0045296	cadherin binding	36/469	334/18639	0.107784431137725	4.28356932191055	1.98670445619926e-13	2.18537490181919e-11
GO:0023026	MHC class II protein complex binding	12/469	27/18639	0.444444444444444	17.6631130063966	6.91722776008316e-13	6.52195760236412e-11
GO:0022853	active monoatomic ion transmembrane transporter activity	20/469	118/18639	0.169491525423729	6.73593292616819	1.45407384407773e-11	1.19961092136413e-09
GO:0023023	MHC protein complex binding	12/469	37/18639	0.324324324324324	12.8892986803435	5.86456156570351e-11	4.30067848151591e-09
GO:0004857	enzyme inhibitor activity	36/469	416/18639	0.0865384615384615	3.43921190749549	1.19887578463819e-10	7.91258017861203e-09
GO:0004129	cytochrome-c oxidase activity	8/469	15/18639	0.533333333333333	21.1957356076759	8.34782027998737e-10	4.59130115399306e-08
GO:0055105	ubiquitin-protein transferase inhibitor activity	8/469	15/18639	0.533333333333333	21.1957356076759	8.34782027998737e-10	4.59130115399306e-08
GO:0015399	primary active transmembrane transporter activity	21/469	166/18639	0.126506024096386	5.02760294910987	1.26089654732848e-09	6.40147477874459e-08
GO:0051082	unfolded protein binding	18/469	121/18639	0.148760330578512	5.91203369222365	1.38797334908362e-09	6.5433029313942e-08
GO:0016675	oxidoreductase activity, acting on a heme group of donors	8/469	16/18639	0.5	19.8710021321962	1.63290369583541e-09	7.18477626167582e-08
GO:1990948	ubiquitin ligase inhibitor activity	7/469	11/18639	0.636363636363636	25.2903663500678	1.84769576760805e-09	7.6217450413832e-08
GO:0048027	mRNA 5'-UTR binding	8/469	24/18639	0.333333333333333	13.2473347547974	7.81435160046846e-08	3.03380709194658e-06
GO:0042277	peptide binding	23/469	249/18639	0.0923694779116466	3.67094818506435	8.89526168255566e-08	3.26159595027041e-06
GO:0050840	extracellular matrix binding	12/469	67/18639	0.17910447761194	7.11797091302549	9.57447058718329e-08	3.32586873028472e-06
GO:0005178	integrin binding	18/469	161/18639	0.111801242236025	4.44320544570846	1.32523660082724e-07	4.3732807827299e-06
GO:0005520	insulin-like growth factor binding	7/469	19/18639	0.368421052631579	14.6417910447761	2.36816129381372e-07	7.44279263770025e-06
GO:0061134	peptidase regulator activity	21/469	226/18639	0.0929203539823009	3.69284110421345	2.93239622146197e-07	8.7971886643859e-06
GO:0019838	growth factor binding	16/469	136/18639	0.117647058823529	4.67552991345792	3.27854061943178e-07	9.40798612532598e-06
GO:0031994	insulin-like growth factor I binding	6/469	13/18639	0.461538461538462	18.3424635066426	3.63125165006118e-07	9.98594203766824e-06
GO:0001968	fibronectin binding	8/469	30/18639	0.266666666666667	10.597867803838	5.44516971794717e-07	1.43752480553805e-05
GO:0008137	NADH dehydrogenase (ubiquinone) activity	9/469	41/18639	0.219512195121951	8.72385459462271	6.41443586045084e-07	1.62827987226829e-05
GO:0003954	NADH dehydrogenase activity	9/469	44/18639	0.204545454545455	8.12904632680752	1.21388836522355e-06	2.96728267054646e-05
GO:0016209	antioxidant activity	12/469	86/18639	0.13953488372093	5.5453959438687	1.58428015138458e-06	3.73437464254938e-05
GO:0055106	ubiquitin-protein transferase regulator activity	8/469	36/18639	0.222222222222222	8.83155650319829	2.46554815062432e-06	5.61124751521397e-05
GO:0050750	low-density lipoprotein particle receptor binding	7/469	26/18639	0.269230769230769	10.6997703788749	2.6534535157664e-06	5.83759773468609e-05
GO:0004859	phospholipase inhibitor activity	5/469	12/18639	0.416666666666667	16.5591684434968	6.75743428681082e-06	0.000143867955783714
GO:0008201	heparin binding	16/469	172/18639	0.0930232558139535	3.6969306292458	7.4802555011519e-06	0.000154280269711258
GO:0031625	ubiquitin protein ligase binding	22/469	302/18639	0.0728476821192053	2.89511289343255	8.90367100342396e-06	0.000178073420068479
GO:0070325	lipoprotein particle receptor binding	7/469	31/18639	0.225806451612903	8.9740009629273	9.51248169073529e-06	0.000184654056349567
GO:0005539	glycosaminoglycan binding	19/469	242/18639	0.0785123966942149	3.12024000422915	1.27520527869829e-05	0.000240467281125964
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	9/469	58/18639	0.155172413793103	6.16686273068157	1.33469175906388e-05	0.000244693489161711
GO:0033218	amide binding	19/469	247/18639	0.0769230769230769	3.0570772511071	1.70115134118366e-05	0.000303448617616545
GO:0005201	extracellular matrix structural constituent	15/469	168/18639	0.0892857142857143	3.54839323789217	2.34071489108353e-05	0.000388533125795156
GO:0031386	protein tag activity	5/469	15/18639	0.333333333333333	13.2473347547974	2.40667611107089e-05	0.000388533125795156
GO:0141047	molecular tag activity	5/469	15/18639	0.333333333333333	13.2473347547974	2.40667611107089e-05	0.000388533125795156
GO:0044389	ubiquitin-like protein ligase binding	22/469	322/18639	0.0683229813664596	2.71529221682184	2.41361487236385e-05	0.000388533125795156
GO:0055102	lipase inhibitor activity	5/469	16/18639	0.3125	12.4193763326226	3.4283952492578e-05	0.000538747824883369
GO:0008135	translation factor activity, RNA binding	10/469	83/18639	0.120481927710843	4.78819328486655	4.35069168755716e-05	0.000667780584601797
GO:0180051	translation factor activity	10/469	84/18639	0.119047619047619	4.73119098385623	4.82935650085533e-05	0.000724403475128299
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	5/469	18/18639	0.277777777777778	11.0394456289979	6.45053629492153e-05	0.000946078656588491
GO:0016651	oxidoreductase activity, acting on NAD(P)H	10/469	88/18639	0.113636363636364	4.5161368482264	7.21940873119426e-05	0.00103582820925831
GO:0005518	collagen binding	9/469	72/18639	0.125	4.96775053304904	7.81646147275053e-05	0.00109763076000327
GO:0004601	peroxidase activity	8/469	57/18639	0.140350877192982	5.57782515991471	8.47829803018877e-05	0.00116576597915096
GO:0030414	peptidase inhibitor activity	14/469	169/18639	0.0828402366863905	3.2922370396538	9.84365369980098e-05	0.00132587988609564
GO:0044183	protein folding chaperone	9/469	75/18639	0.12	4.76904051172708	0.000107920987084923	0.0014091493607668
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	8/469	59/18639	0.135593220338983	5.38874634093455	0.000108888814241071	0.0014091493607668
GO:0005200	structural constituent of cytoskeleton	11/469	112/18639	0.0982142857142857	3.90323256168139	0.000121593324727656	0.00154329989077409
GO:0002020	protease binding	12/469	136/18639	0.0882352941176471	3.50664743509344	0.000169323131779355	0.00210855220706367
GO:1901681	sulfur compound binding	18/469	275/18639	0.0654545454545455	2.60129482457841	0.00022265270693482	0.00267890274299552
GO:0004866	endopeptidase inhibitor activity	13/469	161/18639	0.0807453416149068	3.20898171078944	0.000223241895249627	0.00267890274299552
GO:0004602	glutathione peroxidase activity	5/469	23/18639	0.217391304347826	8.63956614443311	0.000228325640403698	0.00269098076190073
GO:0001540	amyloid-beta binding	9/469	83/18639	0.108433734939759	4.30937395637989	0.000236596140257329	0.00273953425561118
GO:0061135	endopeptidase regulator activity	14/469	184/18639	0.0760869565217391	3.02384815055159	0.000241026193459224	0.00274271185660497
GO:0008191	metalloendopeptidase inhibitor activity	4/469	14/18639	0.285714285714286	11.3548583612549	0.000324157756846229	0.0036261715172629
GO:0016860	intramolecular oxidoreductase activity	7/469	53/18639	0.132075471698113	5.24894395944804	0.000346071366524709	0.0038067850317718
GO:0097110	scaffold protein binding	8/469	70/18639	0.114285714285714	4.54194334450198	0.000364301934082911	0.00394162748352002
GO:0015252	proton channel activity	5/469	27/18639	0.185185185185185	7.35963041933191	0.000504209169967049	0.0053673879383589
GO:0016504	peptidase activator activity	7/469	57/18639	0.12280701754386	4.88059701492537	0.00054449723737563	0.00570425677250661
GO:0042605	peptide antigen binding	6/469	45/18639	0.133333333333333	5.29893390191898	0.000871321342530962	0.00898550134485054
GO:0003746	translation elongation factor activity	4/469	18/18639	0.222222222222222	8.83155650319829	0.000914850865312392	0.00914850865312392
GO:0098641	cadherin binding involved in cell-cell adhesion	4/469	18/18639	0.222222222222222	8.83155650319829	0.000914850865312392	0.00914850865312392
GO:0003756	protein disulfide isomerase activity	4/469	19/18639	0.210526315789474	8.36673773987207	0.00113594708915867	0.01102536880654
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/469	19/18639	0.210526315789474	8.36673773987207	0.00113594708915867	0.01102536880654
GO:0022804	active transmembrane transporter activity	23/469	457/18639	0.050328227571116	2.0001446347506	0.0013580041758248	0.0129896051600633
GO:0015035	protein-disulfide reductase activity	5/469	34/18639	0.147058823529412	5.8444123918224	0.00150393333287529	0.0141799428528241
GO:0032395	MHC class II receptor activity	3/469	10/18639	0.3	11.9226012793177	0.00166487030548673	0.0154762591777639
GO:0003743	translation initiation factor activity	6/469	51/18639	0.117647058823529	4.67552991345792	0.00169722612822407	0.0155579061753873
GO:0030021	extracellular matrix structural constituent conferring compression resistance	4/469	22/18639	0.181818181818182	7.22581895716224	0.00201962519751539	0.0182596250734268
GO:0043022	ribosome binding	9/469	112/18639	0.0803571428571429	3.19355391410295	0.00208787513008446	0.0186215889980506
GO:0043394	proteoglycan binding	5/469	37/18639	0.135135135135135	5.37054111680977	0.00221485242321633	0.0194907013243037
GO:0004867	serine-type endopeptidase inhibitor activity	8/469	95/18639	0.0842105263157895	3.34669509594883	0.00272122678851605	0.0236317063213236
GO:0097371	MDM2/MDM4 family protein binding	3/469	12/18639	0.25	9.93550106609808	0.00293990451176277	0.0251991815293952
GO:0015036	disulfide oxidoreductase activity	5/469	40/18639	0.125	4.96775053304904	0.00314356600964007	0.0265994046969545
GO:0042287	MHC protein binding	5/469	41/18639	0.121951219512195	4.8465858859015	0.00350746073849775	0.0293028365494749
GO:0048306	calcium-dependent protein binding	7/469	80/18639	0.0875	3.47742537313433	0.0039937013516752	0.0329480361513204
GO:0008200	ion channel inhibitor activity	5/469	43/18639	0.116279069767442	4.62116328655725	0.00432435396418167	0.035235476745184
GO:0008320	protein transmembrane transporter activity	4/469	27/18639	0.148148148148148	5.88770433546553	0.00438825341480435	0.0353200884606204
GO:0044548	S100 protein binding	3/469	14/18639	0.214285714285714	8.51614377094121	0.00468560511976005	0.0371143179402854
GO:0016248	channel inhibitor activity	5/469	44/18639	0.113636363636364	4.5161368482264	0.00477987428018827	0.0371143179402854
GO:0030547	signaling receptor inhibitor activity	5/469	44/18639	0.113636363636364	4.5161368482264	0.00477987428018827	0.0371143179402854
GO:0005507	copper ion binding	6/469	63/18639	0.0952380952380952	3.78495278708498	0.00497534985083324	0.038182917459883
GO:0141110	transporter inhibitor activity	5/469	45/18639	0.111111111111111	4.41577825159915	0.00526844339739544	0.0396891731024218
GO:0043021	ribonucleoprotein complex binding	11/469	177/18639	0.0621468926553672	2.46984207292834	0.00529188974698958	0.0396891731024218
GO:0043236	laminin binding	4/469	29/18639	0.137931034482759	5.48165576060584	0.00570866652969784	0.0423339315685458
GO:0005496	steroid binding	8/469	108/18639	0.0740740740740741	2.94385216773276	0.00594882423994831	0.0436247110929543
GO:0140375	immune receptor activity	10/469	156/18639	0.0641025641025641	2.54756437592258	0.00620198186390307	0.0449814069250112
GO:0005504	fatty acid binding	5/469	47/18639	0.106382978723404	4.22787279408429	0.00634965422132615	0.0455518672399484
GO:0051087	protein-folding chaperone binding	9/469	134/18639	0.0671641791044776	2.66923909238456	0.00685196124696257	0.0486268217526376
GO:0008142	oxysterol binding	3/469	16/18639	0.1875	7.45162579957356	0.00694462556194843	0.0487601369243187
GO:0032934	sterol binding	6/469	68/18639	0.0882352941176471	3.50664743509344	0.00721845767052327	0.0501492848688985
GO:0022884	macromolecule transmembrane transporter activity	4/469	32/18639	0.125	4.96775053304904	0.00814684626266038	0.0557444942512993
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/469	17/18639	0.176470588235294	7.01329487018688	0.00827721278276868	0.0557444942512993
GO:1990226	histone methyltransferase binding	3/469	17/18639	0.176470588235294	7.01329487018688	0.00827721278276868	0.0557444942512993
GO:0042562	hormone binding	7/469	94/18639	0.074468085106383	2.959510955859	0.0095517346998515	0.0636782313323433
GO:0019955	cytokine binding	9/469	144/18639	0.0625	2.48387526652452	0.0107426037666972	0.0709011848602012
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	5/469	54/18639	0.0925925925925926	3.67981520966596	0.0113508950740635	0.0741741658305139
GO:0098631	cell adhesion mediator activity	6/469	76/18639	0.0789473684210526	3.13752665245203	0.012202622676496	0.0783981674360063
GO:0140313	molecular sequestering activity	5/469	55/18639	0.0909090909090909	3.61290947858112	0.012234865524104	0.0783981674360063
GO:0016505	peptidase activator activity involved in apoptotic process	3/469	20/18639	0.15	5.96130063965885	0.0131246702812382	0.0824979274820688
GO:0042288	MHC class I protein binding	3/469	20/18639	0.15	5.96130063965885	0.0131246702812382	0.0824979274820688
GO:0033293	monocarboxylic acid binding	6/469	79/18639	0.0759493670886076	3.01838007071334	0.0145770464883951	0.0907627422862334
GO:0072542	protein phosphatase activator activity	3/469	21/18639	0.142857142857143	5.67742918062747	0.0150311834709248	0.0927157111290688
GO:0016853	isomerase activity	10/469	180/18639	0.0555555555555556	2.20788912579957	0.0159577249285873	0.0975194301191444
GO:0001786	phosphatidylserine binding	5/469	59/18639	0.0847457627118644	3.3679664630841	0.0162356435725483	0.0983075665860726
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	4/469	40/18639	0.1	3.97420042643923	0.0176985725946379	0.105234755968117
GO:0140662	ATP-dependent protein folding chaperone	4/469	40/18639	0.1	3.97420042643923	0.0176985725946379	0.105234755968117
GO:0019888	protein phosphatase regulator activity	7/469	107/18639	0.0654205607476635	2.59994420421258	0.0184825949952907	0.108915291936534
GO:0140318	protein transporter activity	4/469	41/18639	0.0975609756097561	3.8772687087212	0.0192327468493558	0.110701942975568
GO:0005212	structural constituent of eye lens	3/469	23/18639	0.130434782608696	5.18373968665987	0.0192889749124097	0.110701942975568
GO:0017134	fibroblast growth factor binding	3/469	23/18639	0.130434782608696	5.18373968665987	0.0192889749124097	0.110701942975568
GO:0008307	structural constituent of muscle	4/469	42/18639	0.0952380952380952	3.78495278708498	0.0208466533421207	0.117596506032476
GO:0042056	chemoattractant activity	4/469	42/18639	0.0952380952380952	3.78495278708498	0.0208466533421207	0.117596506032476
GO:0005126	cytokine receptor binding	13/469	275/18639	0.0472727272727273	1.87871292886218	0.0224629235956958	0.125018687219122
GO:0048156	tau protein binding	4/469	43/18639	0.0930232558139535	3.6969306292458	0.0225412481501144	0.125018687219122
GO:0140297	DNA-binding transcription factor binding	20/469	488/18639	0.040983606557377	1.62877066657346	0.0229760464055293	0.126368255230411
GO:0004197	cysteine-type endopeptidase activity	6/469	88/18639	0.0681818181818182	2.70968210893584	0.0235869230481535	0.128395795635925
GO:0001848	complement binding	3/469	25/18639	0.12	4.76904051172708	0.0241441486142976	0.128395795635925
GO:0019211	phosphatase activator activity	3/469	25/18639	0.12	4.76904051172708	0.0241441486142976	0.128395795635925
GO:0120020	cholesterol transfer activity	3/469	25/18639	0.12	4.76904051172708	0.0241441486142976	0.128395795635925
GO:0001223	transcription coactivator binding	4/469	44/18639	0.0909090909090909	3.61290947858112	0.024317385537107	0.128395795635925
GO:0008009	chemokine activity	4/469	45/18639	0.0888888888888889	3.53262260127932	0.0261758189165911	0.136381941175214
GO:0001221	transcription coregulator binding	7/469	115/18639	0.0608695652173913	2.41907852044127	0.0262431917109881	0.136381941175214
GO:0043548	phosphatidylinositol 3-kinase binding	3/469	26/18639	0.115384615384615	4.58561587666065	0.026796058504953	0.137096113281155
GO:0097602	cullin family protein binding	3/469	26/18639	0.115384615384615	4.58561587666065	0.026796058504953	0.137096113281155
GO:0072341	modified amino acid binding	6/469	91/18639	0.0659340659340659	2.62035192952037	0.0272698512931475	0.138446937334441
GO:0004175	endopeptidase activity	17/469	405/18639	0.0419753086419753	1.66818289504857	0.0281685608761433	0.14191794029202
GO:0019208	phosphatase regulator activity	7/469	117/18639	0.0598290598290598	2.37772675086108	0.0284845374767022	0.142422687383511
GO:0004364	glutathione transferase activity	3/469	27/18639	0.111111111111111	4.41577825159915	0.0295970341412216	0.143000090160253
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/469	11/18639	0.181818181818182	7.22581895716224	0.0299000188516893	0.143000090160253
GO:0042608	T cell receptor binding	2/469	11/18639	0.181818181818182	7.22581895716224	0.0299000188516893	0.143000090160253
GO:0050786	RAGE receptor binding	2/469	11/18639	0.181818181818182	7.22581895716224	0.0299000188516893	0.143000090160253
GO:0050998	nitric-oxide synthase binding	2/469	11/18639	0.181818181818182	7.22581895716224	0.0299000188516893	0.143000090160253
GO:0097493	structural molecule activity conferring elasticity	2/469	11/18639	0.181818181818182	7.22581895716224	0.0299000188516893	0.143000090160253
GO:0019207	kinase regulator activity	13/469	287/18639	0.0452961672473868	1.80016047190627	0.0303706811869566	0.144206112110729
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	15/469	349/18639	0.0429799426934097	1.70810906580483	0.0315827711562352	0.148890206879394
GO:0097718	disordered domain specific binding	3/469	28/18639	0.107142857142857	4.25807188547061	0.0325463477135076	0.152344606318546
GO:0004896	cytokine receptor activity	6/469	96/18639	0.0625	2.48387526652452	0.0342173267965957	0.159038279477135
GO:0005048	signal sequence binding	4/469	51/18639	0.0784313725490196	3.11701994230528	0.0390844459322197	0.180389750456399
GO:0003725	double-stranded RNA binding	5/469	75/18639	0.0666666666666667	2.64946695095949	0.0405625065544816	0.185463502949265
GO:0019855	calcium channel inhibitor activity	2/469	13/18639	0.153846153846154	6.1141545022142	0.0410267748948375	0.185463502949265
GO:0043560	insulin receptor substrate binding	2/469	13/18639	0.153846153846154	6.1141545022142	0.0410267748948375	0.185463502949265
GO:0004864	protein phosphatase inhibitor activity	4/469	53/18639	0.0754716981132075	2.99939654825602	0.0440641384312982	0.195183431977563
GO:0005544	calcium-dependent phospholipid binding	4/469	53/18639	0.0754716981132075	2.99939654825602	0.0440641384312982	0.195183431977563
GO:0017046	peptide hormone binding	4/469	53/18639	0.0754716981132075	2.99939654825602	0.0440641384312982	0.195183431977563
GO:0031369	translation initiation factor binding	3/469	32/18639	0.09375	3.72581289978678	0.0458034342660376	0.198883332997269
GO:0051059	NF-kappaB binding	3/469	32/18639	0.09375	3.72581289978678	0.0458034342660376	0.198883332997269
GO:0120015	sterol transfer activity	3/469	32/18639	0.09375	3.72581289978678	0.0458034342660376	0.198883332997269
GO:0015485	cholesterol binding	4/469	54/18639	0.0740740740740741	2.94385216773276	0.046681197899877	0.200485161973234
GO:0008494	translation activator activity	2/469	14/18639	0.142857142857143	5.67742918062747	0.0470836365240171	0.200485161973234
GO:0032036	myosin heavy chain binding	2/469	14/18639	0.142857142857143	5.67742918062747	0.0470836365240171	0.200485161973234
GO:0031406	carboxylic acid binding	9/469	187/18639	0.0481283422459893	1.91271678277824	0.0474142525046278	0.200598760596502
GO:0046332	SMAD binding	5/469	79/18639	0.0632911392405063	2.51531672559445	0.048901409093973	0.204761338887263
GO:0098632	cell-cell adhesion mediator activity	4/469	55/18639	0.0727272727272727	2.8903275828649	0.0493828710273886	0.204761338887263
GO:0140311	protein sequestering activity	3/469	33/18639	0.0909090909090909	3.61290947858112	0.0494747846340135	0.204761338887263
GO:0099106	ion channel regulator activity	8/469	160/18639	0.05	1.98710021321962	0.0496391124575184	0.204761338887263
GO:0043177	organic acid binding	9/469	189/18639	0.0476190476190476	1.89247639354249	0.0501016078891459	0.205385473334387
GO:0019212	phosphatase inhibitor activity	4/469	56/18639	0.0714285714285714	2.83871459031374	0.052168909934778	0.212540003437984
GO:0005523	tropomyosin binding	2/469	15/18639	0.133333333333333	5.29893390191898	0.0534428596875772	0.216394401188963
GO:0005525	GTP binding	15/469	378/18639	0.0396825396825397	1.57706366128541	0.0561742706650923	0.226067186822933
GO:0003713	transcription coactivator activity	11/469	256/18639	0.04296875	1.70766424573561	0.0598783418302317	0.233913199593151
GO:0005159	insulin-like growth factor receptor binding	2/469	16/18639	0.125	4.96775053304904	0.060085464562667	0.233913199593151
GO:0034450	ubiquitin-ubiquitin ligase activity	2/469	16/18639	0.125	4.96775053304904	0.060085464562667	0.233913199593151
GO:0043023	ribosomal large subunit binding	2/469	16/18639	0.125	4.96775053304904	0.060085464562667	0.233913199593151
GO:0004860	protein kinase inhibitor activity	5/469	84/18639	0.0595238095238095	2.36559549192811	0.0606438901462266	0.233913199593151
GO:0051117	ATPase binding	5/469	84/18639	0.0595238095238095	2.36559549192811	0.0606438901462266	0.233913199593151
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	3/469	36/18639	0.0833333333333333	3.31183368869936	0.0613136114085077	0.233913199593151
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	3/469	36/18639	0.0833333333333333	3.31183368869936	0.0613136114085077	0.233913199593151
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	3/469	36/18639	0.0833333333333333	3.31183368869936	0.0613136114085077	0.233913199593151
GO:0016247	channel regulator activity	8/469	168/18639	0.0476190476190476	1.89247639354249	0.062499586861434	0.237067398439922
GO:0141108	transporter regulator activity	8/469	170/18639	0.0470588235294118	1.87021196538317	0.0660113257140927	0.247014149541851
GO:0008429	phosphatidylethanolamine binding	2/469	17/18639	0.117647058823529	4.67552991345792	0.0669932314666535	0.247014149541851
GO:0016018	cyclosporin A binding	2/469	17/18639	0.117647058823529	4.67552991345792	0.0669932314666535	0.247014149541851
GO:0048038	quinone binding	2/469	17/18639	0.117647058823529	4.67552991345792	0.0669932314666535	0.247014149541851
GO:0070492	oligosaccharide binding	2/469	17/18639	0.117647058823529	4.67552991345792	0.0669932314666535	0.247014149541851
GO:0019903	protein phosphatase binding	7/469	144/18639	0.0486111111111111	1.93190298507463	0.0719077742483833	0.263661838910739
GO:0035615	clathrin adaptor activity	2/469	18/18639	0.111111111111111	4.41577825159915	0.0741486747542027	0.268104848711532
GO:1990381	ubiquitin-specific protease binding	2/469	18/18639	0.111111111111111	4.41577825159915	0.0741486747542027	0.268104848711532
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3/469	39/18639	0.0769230769230769	3.0570772511071	0.0743381625972884	0.268104848711532
GO:0019210	kinase inhibitor activity	5/469	90/18639	0.0555555555555556	2.20788912579957	0.0766626768673937	0.274985688763477
GO:0038024	cargo receptor activity	4/469	65/18639	0.0615384615384615	2.44566180088568	0.0809619481327344	0.287673088963535
GO:0097001	ceramide binding	2/469	19/18639	0.105263157894737	4.18336886993603	0.0815350175422599	0.287673088963535
GO:0019001	guanyl nucleotide binding	15/469	400/18639	0.0375	1.49032515991471	0.0819432435229463	0.287673088963535
GO:0032561	guanyl ribonucleotide binding	15/469	400/18639	0.0375	1.49032515991471	0.0819432435229463	0.287673088963535
GO:0043178	alcohol binding	5/469	92/18639	0.0543478260869565	2.15989153610828	0.0824629184972173	0.28796574713314
GO:0016859	cis-trans isomerase activity	3/469	42/18639	0.0714285714285714	2.83871459031374	0.0884740774714331	0.307331005953399
GO:0043024	ribosomal small subunit binding	2/469	20/18639	0.1	3.97420042643923	0.0891361672379289	0.308009792549912
GO:0001846	opsonin binding	2/469	21/18639	0.0952380952380952	3.78495278708498	0.096936691844982	0.32978462174066
GO:0070182	DNA polymerase binding	2/469	21/18639	0.0952380952380952	3.78495278708498	0.096936691844982	0.32978462174066
GO:0140312	cargo adaptor activity	2/469	21/18639	0.0952380952380952	3.78495278708498	0.096936691844982	0.32978462174066
GO:0008234	cysteine-type peptidase activity	8/469	187/18639	0.0427807486631016	1.70019269580288	0.100705906677802	0.340850761063329
GO:0042379	chemokine receptor binding	4/469	72/18639	0.0555555555555556	2.20788912579957	0.10774174866796	0.362803847555377
GO:0019887	protein kinase regulator activity	10/469	255/18639	0.0392156862745098	1.55850997115264	0.111330510201073	0.372985465648264
GO:0031072	heat shock protein binding	6/469	131/18639	0.0458015267175573	1.82024447012484	0.113323930578157	0.377746435260523
GO:0035035	histone acetyltransferase binding	2/469	24/18639	0.0833333333333333	3.31183368869936	0.121389627518552	0.400585770811222
GO:0050431	transforming growth factor beta binding	2/469	24/18639	0.0833333333333333	3.31183368869936	0.121389627518552	0.400585770811222
GO:0017022	myosin binding	4/469	76/18639	0.0526315789473684	2.09168443496802	0.124613505729136	0.409178675528505
GO:0060590	ATPase regulator activity	3/469	49/18639	0.0612244897959184	2.43318393455463	0.125310734082935	0.409431111360085
GO:0044325	transmembrane transporter binding	6/469	136/18639	0.0441176470588235	1.75332371754672	0.128928576691511	0.419176653282744
GO:0048020	CCR chemokine receptor binding	3/469	50/18639	0.06	2.38452025586354	0.13096534078521	0.423711396658033
GO:0003924	GTPase activity	12/469	331/18639	0.0362537764350453	1.4407977376819	0.132381110909366	0.426202600976497
GO:0005125	cytokine activity	9/469	234/18639	0.0384615384615385	1.52853862555355	0.137385535521042	0.435075868605985
GO:0016835	carbon-oxygen lyase activity	4/469	79/18639	0.0506329113924051	2.01225338047556	0.137952830701219	0.435075868605985
GO:0030247	polysaccharide binding	2/469	26/18639	0.0769230769230769	3.0570772511071	0.138433230920086	0.435075868605985
GO:0050681	nuclear androgen receptor binding	2/469	26/18639	0.0769230769230769	3.0570772511071	0.138433230920086	0.435075868605985
GO:0070412	R-SMAD binding	2/469	26/18639	0.0769230769230769	3.0570772511071	0.138433230920086	0.435075868605985
GO:0000049	tRNA binding	4/469	80/18639	0.05	1.98710021321962	0.142522322176897	0.443741040903065
GO:0005080	protein kinase C binding	3/469	52/18639	0.0576923076923077	2.29280793833033	0.142535001017348	0.443741040903065
GO:0004222	metalloendopeptidase activity	5/469	110/18639	0.0454545454545455	1.80645473929056	0.144347452015931	0.447273794978943
GO:0001671	ATPase activator activity	2/469	27/18639	0.0740740740740741	2.94385216773276	0.147140126662395	0.451685970219445
GO:0008266	poly(U) RNA binding	2/469	27/18639	0.0740740740740741	2.94385216773276	0.147140126662395	0.451685970219445
GO:0005246	calcium channel regulator activity	3/469	53/18639	0.0566037735849057	2.24954741119202	0.148443252772511	0.453576605693784
GO:0003823	antigen binding	7/469	174/18639	0.0402298850574713	1.59881626351004	0.15016850842981	0.456733712274997
GO:0003779	actin binding	15/469	443/18639	0.0338600451467269	1.34566605861374	0.151467270119435	0.458570634306547
GO:0046625	sphingolipid binding	2/469	28/18639	0.0714285714285714	2.83871459031374	0.155955032735387	0.469308564464056
GO:0004252	serine-type endopeptidase activity	7/469	176/18639	0.0397727272727273	1.58064789687924	0.156436188154685	0.469308564464056
GO:0003785	actin monomer binding	2/469	29/18639	0.0689655172413793	2.74082788030292	0.164867034920621	0.487947278240404
GO:0004629	phospholipase C activity	2/469	29/18639	0.0689655172413793	2.74082788030292	0.164867034920621	0.487947278240404
GO:0051861	glycolipid binding	2/469	29/18639	0.0689655172413793	2.74082788030292	0.164867034920621	0.487947278240404
GO:0030246	carbohydrate binding	10/469	280/18639	0.0357142857142857	1.41935729515687	0.170020315094464	0.499381899390306
GO:0019209	kinase activator activity	6/469	148/18639	0.0405405405405405	1.61116233504293	0.170243829337604	0.499381899390306
GO:0001965	G-protein alpha-subunit binding	2/469	30/18639	0.0666666666666667	2.64946695095949	0.173865697724327	0.501097644096312
GO:0008187	poly-pyrimidine tract binding	2/469	30/18639	0.0666666666666667	2.64946695095949	0.173865697724327	0.501097644096312
GO:0031210	phosphatidylcholine binding	2/469	30/18639	0.0666666666666667	2.64946695095949	0.173865697724327	0.501097644096312
GO:0048019	receptor antagonist activity	2/469	30/18639	0.0666666666666667	2.64946695095949	0.173865697724327	0.501097644096312
GO:0008237	metallopeptidase activity	7/469	184/18639	0.0380434782608696	1.51192407527579	0.182659030861883	0.524152001603665
GO:0004879	nuclear receptor activity	3/469	59/18639	0.0508474576271186	2.02077987785046	0.185407597580206	0.527452648288518
GO:0015459	potassium channel regulator activity	3/469	59/18639	0.0508474576271186	2.02077987785046	0.185407597580206	0.527452648288518
GO:0098531	ligand-modulated transcription factor activity	3/469	60/18639	0.05	1.98710021321962	0.191789625198004	0.539468707143375
GO:0071813	lipoprotein particle binding	2/469	32/18639	0.0625	2.48387526652452	0.192083554816202	0.539468707143375
GO:0071814	protein-lipid complex binding	2/469	32/18639	0.0625	2.48387526652452	0.192083554816202	0.539468707143375
GO:0015026	coreceptor activity	3/469	61/18639	0.0491803278688525	1.95452479988815	0.198226128382421	0.552022129672566
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	3/469	61/18639	0.0491803278688525	1.95452479988815	0.198226128382421	0.552022129672566
GO:0019902	phosphatase binding	7/469	190/18639	0.0368421052631579	1.46417910447761	0.203446564256698	0.564179547938743
GO:0051427	hormone receptor binding	2/469	34/18639	0.0588235294117647	2.33776495672896	0.210534058644025	0.56681900415776
GO:0003730	mRNA 3'-UTR binding	9/469	262/18639	0.0343511450381679	1.36518335259363	0.216098356616448	0.56681900415776
GO:0008236	serine-type peptidase activity	7/469	194/18639	0.0360824742268041	1.43398984459148	0.217786835731223	0.56681900415776
GO:0046982	protein heterodimerization activity	12/469	369/18639	0.032520325203252	1.29242290290707	0.221398418019953	0.56681900415776
GO:0120013	lipid transfer activity	3/469	65/18639	0.0461538461538462	1.83424635066426	0.224453240276814	0.56681900415776
GO:0001094	TFIID-class transcription factor complex binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0003796	lysozyme activity	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0004955	prostaglandin receptor activity	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0005131	growth hormone receptor binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0005381	iron ion transmembrane transporter activity	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0005522	profilin binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0005528	FK506 binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0030957	Tat protein binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0031996	thioesterase binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0032356	oxidized DNA binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0035374	chondroitin sulfate binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0043208	glycosphingolipid binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0050815	phosphoserine residue binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0070097	delta-catenin binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0070513	death domain binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0097177	mitochondrial ribosome binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0098505	G-rich strand telomeric DNA binding	1/469	10/18639	0.1	3.97420042643923	0.225009968317171	0.56681900415776
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/469	36/18639	0.0555555555555556	2.20788912579957	0.229149285490683	0.572283105510833
GO:0044390	ubiquitin-like protein conjugating enzyme binding	2/469	36/18639	0.0555555555555556	2.20788912579957	0.229149285490683	0.572283105510833
GO:0017171	serine hydrolase activity	7/469	198/18639	0.0353535353535354	1.40502035278155	0.232478412039789	0.572283105510833
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	3/469	67/18639	0.0447761194029851	1.77949272825637	0.237812028179504	0.572283105510833
GO:0001851	complement component C3b binding	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0003953	NAD+ nucleosidase activity	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0004954	prostanoid receptor activity	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0008199	ferric iron binding	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0008432	JUN kinase binding	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0008526	phosphatidylinositol transfer activity	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0010854	adenylate cyclase regulator activity	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0015217	ADP transmembrane transporter activity	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0019215	intermediate filament binding	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0032050	clathrin heavy chain binding	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0032794	GTPase activating protein binding	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0034511	U3 snoRNA binding	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0034713	type I transforming growth factor beta receptor binding	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0048185	activin binding	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/469	11/18639	0.0909090909090909	3.61290947858112	0.24452096326372	0.572283105510833
GO:0005501	retinoid binding	2/469	38/18639	0.0526315789473684	2.09168443496802	0.247867461567688	0.574008858367279
GO:0019840	isoprenoid binding	2/469	38/18639	0.0526315789473684	2.09168443496802	0.247867461567688	0.574008858367279
GO:0042162	telomeric DNA binding	2/469	38/18639	0.0526315789473684	2.09168443496802	0.247867461567688	0.574008858367279
GO:0000217	DNA secondary structure binding	2/469	39/18639	0.0512820512820513	2.03805150073807	0.257247423674197	0.583683124317778
GO:0003995	acyl-CoA dehydrogenase activity	1/469	12/18639	0.0833333333333333	3.31183368869936	0.263541774313178	0.583683124317778
GO:0005049	nuclear export signal receptor activity	1/469	12/18639	0.0833333333333333	3.31183368869936	0.263541774313178	0.583683124317778
GO:0005165	neurotrophin receptor binding	1/469	12/18639	0.0833333333333333	3.31183368869936	0.263541774313178	0.583683124317778
GO:0005527	macrolide binding	1/469	12/18639	0.0833333333333333	3.31183368869936	0.263541774313178	0.583683124317778
GO:0010853	cyclase activator activity	1/469	12/18639	0.0833333333333333	3.31183368869936	0.263541774313178	0.583683124317778
GO:0031543	peptidyl-proline dioxygenase activity	1/469	12/18639	0.0833333333333333	3.31183368869936	0.263541774313178	0.583683124317778
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/469	12/18639	0.0833333333333333	3.31183368869936	0.263541774313178	0.583683124317778
GO:0035259	nuclear glucocorticoid receptor binding	1/469	12/18639	0.0833333333333333	3.31183368869936	0.263541774313178	0.583683124317778
GO:0035497	cAMP response element binding	1/469	12/18639	0.0833333333333333	3.31183368869936	0.263541774313178	0.583683124317778
GO:0043047	single-stranded telomeric DNA binding	1/469	12/18639	0.0833333333333333	3.31183368869936	0.263541774313178	0.583683124317778
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/469	12/18639	0.0833333333333333	3.31183368869936	0.263541774313178	0.583683124317778
GO:1990459	transferrin receptor binding	1/469	12/18639	0.0833333333333333	3.31183368869936	0.263541774313178	0.583683124317778
GO:0050997	quaternary ammonium group binding	2/469	40/18639	0.05	1.98710021321962	0.266632521668276	0.586591547670208
GO:0071855	neuropeptide receptor binding	2/469	40/18639	0.05	1.98710021321962	0.266632521668276	0.586591547670208
GO:0005543	phospholipid binding	15/469	497/18639	0.0301810865191147	1.19945686914665	0.271617538450102	0.595573340123146
GO:0051015	actin filament binding	7/469	209/18639	0.0334928229665072	1.33107191316147	0.274440206043282	0.596717615431751
GO:0001530	lipopolysaccharide binding	2/469	41/18639	0.0487804878048781	1.9386343543606	0.276016571642214	0.596717615431751
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/469	13/18639	0.0769230769230769	3.0570772511071	0.282084690931373	0.596717615431751
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/469	13/18639	0.0769230769230769	3.0570772511071	0.282084690931373	0.596717615431751
GO:0005542	folic acid binding	1/469	13/18639	0.0769230769230769	3.0570772511071	0.282084690931373	0.596717615431751
GO:0008035	high-density lipoprotein particle binding	1/469	13/18639	0.0769230769230769	3.0570772511071	0.282084690931373	0.596717615431751
GO:0030955	potassium ion binding	1/469	13/18639	0.0769230769230769	3.0570772511071	0.282084690931373	0.596717615431751
GO:0039706	co-receptor binding	1/469	13/18639	0.0769230769230769	3.0570772511071	0.282084690931373	0.596717615431751
GO:0045159	myosin II binding	1/469	13/18639	0.0769230769230769	3.0570772511071	0.282084690931373	0.596717615431751
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/469	13/18639	0.0769230769230769	3.0570772511071	0.282084690931373	0.596717615431751
GO:0071837	HMG box domain binding	1/469	13/18639	0.0769230769230769	3.0570772511071	0.282084690931373	0.596717615431751
GO:0035198	miRNA binding	2/469	42/18639	0.0476190476190476	1.89247639354249	0.285393696350754	0.599872100609864
GO:0048487	beta-tubulin binding	2/469	42/18639	0.0476190476190476	1.89247639354249	0.285393696350754	0.599872100609864
GO:0004620	phospholipase activity	4/469	109/18639	0.036697247706422	1.45842217484009	0.294410548253658	0.616860196340997
GO:0005347	ATP transmembrane transporter activity	1/469	14/18639	0.0714285714285714	2.83871459031374	0.300161695116555	0.617154887155533
GO:0016530	metallochaperone activity	1/469	14/18639	0.0714285714285714	2.83871459031374	0.300161695116555	0.617154887155533
GO:0019992	diacylglycerol binding	1/469	14/18639	0.0714285714285714	2.83871459031374	0.300161695116555	0.617154887155533
GO:0061783	peptidoglycan muralytic activity	1/469	14/18639	0.0714285714285714	2.83871459031374	0.300161695116555	0.617154887155533
GO:0098847	sequence-specific single stranded DNA binding	1/469	14/18639	0.0714285714285714	2.83871459031374	0.300161695116555	0.617154887155533
GO:1990825	sequence-specific mRNA binding	1/469	14/18639	0.0714285714285714	2.83871459031374	0.300161695116555	0.617154887155533
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0004953	icosanoid receptor activity	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0015929	hexosaminidase activity	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0016846	carbon-sulfur lyase activity	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0017081	chloride channel regulator activity	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0033130	acetylcholine receptor binding	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0047372	monoacylglycerol lipase activity	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0050780	dopamine receptor binding	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0051371	muscle alpha-actinin binding	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0120283	protein serine/threonine kinase binding	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0140776	protein-containing complex destabilizing activity	1/469	15/18639	0.0666666666666667	2.64946695095949	0.317784469075767	0.627957334101815
GO:0004180	carboxypeptidase activity	2/469	46/18639	0.0434782608695652	1.72791322888662	0.322725499542175	0.633925088386416
GO:0030291	protein serine/threonine kinase inhibitor activity	2/469	46/18639	0.0434782608695652	1.72791322888662	0.322725499542175	0.633925088386416
GO:0001618	virus receptor activity	3/469	81/18639	0.037037037037037	1.47192608386638	0.333772633727759	0.642664261013322
GO:0005024	transforming growth factor beta receptor activity	1/469	16/18639	0.0625	2.48387526652452	0.334964402709974	0.642664261013322
GO:0005521	lamin binding	1/469	16/18639	0.0625	2.48387526652452	0.334964402709974	0.642664261013322
GO:0008296	3'-5'-DNA exonuclease activity	1/469	16/18639	0.0625	2.48387526652452	0.334964402709974	0.642664261013322
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/469	16/18639	0.0625	2.48387526652452	0.334964402709974	0.642664261013322
GO:0019841	retinol binding	1/469	16/18639	0.0625	2.48387526652452	0.334964402709974	0.642664261013322
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/469	16/18639	0.0625	2.48387526652452	0.334964402709974	0.642664261013322
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/469	16/18639	0.0625	2.48387526652452	0.334964402709974	0.642664261013322
GO:1990782	protein tyrosine kinase binding	4/469	117/18639	0.0341880341880342	1.35870100049205	0.339989422702414	0.64985503659816
GO:0140272	exogenous protein binding	3/469	82/18639	0.0365853658536585	1.45397576577045	0.340681579792369	0.64985503659816
GO:0001222	transcription corepressor binding	2/469	49/18639	0.0408163265306122	1.62212262303642	0.350405249276291	0.655735357633813
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/469	17/18639	0.0588235294117647	2.33776495672896	0.351712600912682	0.655735357633813
GO:0030169	low-density lipoprotein particle binding	1/469	17/18639	0.0588235294117647	2.33776495672896	0.351712600912682	0.655735357633813
GO:0030548	acetylcholine receptor regulator activity	1/469	17/18639	0.0588235294117647	2.33776495672896	0.351712600912682	0.655735357633813
GO:0032183	SUMO binding	1/469	17/18639	0.0588235294117647	2.33776495672896	0.351712600912682	0.655735357633813
GO:0046965	nuclear retinoid X receptor binding	1/469	17/18639	0.0588235294117647	2.33776495672896	0.351712600912682	0.655735357633813
GO:0051787	misfolded protein binding	1/469	17/18639	0.0588235294117647	2.33776495672896	0.351712600912682	0.655735357633813
GO:0070403	NAD+ binding	1/469	17/18639	0.0588235294117647	2.33776495672896	0.351712600912682	0.655735357633813
GO:0003697	single-stranded DNA binding	4/469	121/18639	0.0330578512396694	1.31378526493859	0.362897617042745	0.662956722384298
GO:0003712	transcription coregulator activity	14/469	495/18639	0.0282828282828283	1.12401628222524	0.365686533149122	0.662956722384298
GO:0000400	four-way junction DNA binding	1/469	18/18639	0.0555555555555556	2.20788912579957	0.36803989068671	0.662956722384298
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/469	18/18639	0.0555555555555556	2.20788912579957	0.36803989068671	0.662956722384298
GO:0008525	phosphatidylcholine transporter activity	1/469	18/18639	0.0555555555555556	2.20788912579957	0.36803989068671	0.662956722384298
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/469	18/18639	0.0555555555555556	2.20788912579957	0.36803989068671	0.662956722384298
GO:0031690	adrenergic receptor binding	1/469	18/18639	0.0555555555555556	2.20788912579957	0.36803989068671	0.662956722384298
GO:0032393	MHC class I receptor activity	1/469	18/18639	0.0555555555555556	2.20788912579957	0.36803989068671	0.662956722384298
GO:0070064	proline-rich region binding	1/469	18/18639	0.0555555555555556	2.20788912579957	0.36803989068671	0.662956722384298
GO:0099602	neurotransmitter receptor regulator activity	1/469	18/18639	0.0555555555555556	2.20788912579957	0.36803989068671	0.662956722384298
GO:1901611	phosphatidylglycerol binding	1/469	18/18639	0.0555555555555556	2.20788912579957	0.36803989068671	0.662956722384298
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	3/469	86/18639	0.0348837209302326	1.38634898596717	0.368245715890168	0.662956722384298
GO:0030544	Hsp70 protein binding	2/469	51/18639	0.0392156862745098	1.55850997115264	0.368644116840966	0.662956722384298
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/469	19/18639	0.0526315789473684	2.09168443496802	0.383956828083624	0.679387416984428
GO:0008301	DNA binding, bending	1/469	19/18639	0.0526315789473684	2.09168443496802	0.383956828083624	0.679387416984428
GO:0016918	retinal binding	1/469	19/18639	0.0526315789473684	2.09168443496802	0.383956828083624	0.679387416984428
GO:0031420	alkali metal ion binding	1/469	19/18639	0.0526315789473684	2.09168443496802	0.383956828083624	0.679387416984428
GO:0043395	heparan sulfate proteoglycan binding	1/469	19/18639	0.0526315789473684	2.09168443496802	0.383956828083624	0.679387416984428
GO:0046624	sphingolipid transporter activity	1/469	19/18639	0.0526315789473684	2.09168443496802	0.383956828083624	0.679387416984428
GO:0051018	protein kinase A binding	2/469	53/18639	0.0377358490566038	1.49969827412801	0.386678490442593	0.680554143178963
GO:0140296	general transcription initiation factor binding	2/469	53/18639	0.0377358490566038	1.49969827412801	0.386678490442593	0.680554143178963
GO:0003727	single-stranded RNA binding	3/469	89/18639	0.0337078651685393	1.33961812127165	0.388788411018201	0.682414775537303
GO:0016829	lyase activity	6/469	200/18639	0.03	1.19226012793177	0.389803591481156	0.682414775537303
GO:0003925	G protein activity	2/469	54/18639	0.037037037037037	1.47192608386638	0.395611153305757	0.686595430417598
GO:0050661	NADP binding	2/469	54/18639	0.037037037037037	1.47192608386638	0.395611153305757	0.686595430417598
GO:0051287	NAD binding	2/469	54/18639	0.037037037037037	1.47192608386638	0.395611153305757	0.686595430417598
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/469	20/18639	0.05	1.98710021321962	0.399473704970239	0.686595430417598
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/469	20/18639	0.05	1.98710021321962	0.399473704970239	0.686595430417598
GO:0010851	cyclase regulator activity	1/469	20/18639	0.05	1.98710021321962	0.399473704970239	0.686595430417598
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/469	20/18639	0.05	1.98710021321962	0.399473704970239	0.686595430417598
GO:0016874	ligase activity	5/469	167/18639	0.029940119760479	1.18988036719737	0.411231593535259	0.699837255021717
GO:0016298	lipase activity	4/469	130/18639	0.0307692307692308	1.22283090044284	0.414220334293495	0.699837255021717
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	4/469	130/18639	0.0307692307692308	1.22283090044284	0.414220334293495	0.699837255021717
GO:0008373	sialyltransferase activity	1/469	21/18639	0.0476190476190476	1.89247639354249	0.414600555626502	0.699837255021717
GO:0036122	BMP binding	1/469	21/18639	0.0476190476190476	1.89247639354249	0.414600555626502	0.699837255021717
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/469	21/18639	0.0476190476190476	1.89247639354249	0.414600555626502	0.699837255021717
GO:0051428	peptide hormone receptor binding	1/469	21/18639	0.0476190476190476	1.89247639354249	0.414600555626502	0.699837255021717
GO:0031683	G-protein beta/gamma-subunit complex binding	1/469	22/18639	0.0454545454545455	1.80645473929056	0.429347163178934	0.715578605298223
GO:0034062	5'-3' RNA polymerase activity	1/469	22/18639	0.0454545454545455	1.80645473929056	0.429347163178934	0.715578605298223
GO:0061133	endopeptidase activator activity	1/469	22/18639	0.0454545454545455	1.80645473929056	0.429347163178934	0.715578605298223
GO:0097747	RNA polymerase activity	1/469	22/18639	0.0454545454545455	1.80645473929056	0.429347163178934	0.715578605298223
GO:0140517	protein-RNA adaptor activity	1/469	22/18639	0.0454545454545455	1.80645473929056	0.429347163178934	0.715578605298223
GO:0061980	regulatory RNA binding	2/469	58/18639	0.0344827586206897	1.37041394015146	0.430714829783783	0.716049842965483
GO:0140104	molecular carrier activity	7/469	249/18639	0.0281124497991968	1.11724509980219	0.437042212416596	0.71955091763308
GO:0045309	protein phosphorylated amino acid binding	2/469	59/18639	0.0338983050847458	1.34718658523364	0.439322101089171	0.71955091763308
GO:0070063	RNA polymerase binding	2/469	59/18639	0.0338983050847458	1.34718658523364	0.439322101089171	0.71955091763308
GO:0070888	E-box binding	2/469	59/18639	0.0338983050847458	1.34718658523364	0.439322101089171	0.71955091763308
GO:0000295	adenine nucleotide transmembrane transporter activity	1/469	23/18639	0.0434782608695652	1.72791322888662	0.443723065873733	0.71955091763308
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/469	23/18639	0.0434782608695652	1.72791322888662	0.443723065873733	0.71955091763308
GO:0005158	insulin receptor binding	1/469	23/18639	0.0434782608695652	1.72791322888662	0.443723065873733	0.71955091763308
GO:0008171	O-methyltransferase activity	1/469	23/18639	0.0434782608695652	1.72791322888662	0.443723065873733	0.71955091763308
GO:0031681	G-protein beta-subunit binding	1/469	23/18639	0.0434782608695652	1.72791322888662	0.443723065873733	0.71955091763308
GO:0099186	structural constituent of postsynapse	1/469	23/18639	0.0434782608695652	1.72791322888662	0.443723065873733	0.71955091763308
GO:0016922	nuclear receptor binding	4/469	137/18639	0.0291970802919708	1.16035048947131	0.453517796155463	0.726218249297417
GO:0016836	hydro-lyase activity	2/469	61/18639	0.0327868852459016	1.30301653325876	0.456319791005216	0.726218249297417
GO:0019905	syntaxin binding	2/469	61/18639	0.0327868852459016	1.30301653325876	0.456319791005216	0.726218249297417
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/469	24/18639	0.0416666666666667	1.65591684434968	0.457737563193523	0.726218249297417
GO:0004622	lysophospholipase activity	1/469	24/18639	0.0416666666666667	1.65591684434968	0.457737563193523	0.726218249297417
GO:0005315	phosphate transmembrane transporter activity	1/469	24/18639	0.0416666666666667	1.65591684434968	0.457737563193523	0.726218249297417
GO:0005540	hyaluronic acid binding	1/469	24/18639	0.0416666666666667	1.65591684434968	0.457737563193523	0.726218249297417
GO:0015295	solute:proton symporter activity	1/469	24/18639	0.0416666666666667	1.65591684434968	0.457737563193523	0.726218249297417
GO:0070300	phosphatidic acid binding	1/469	24/18639	0.0416666666666667	1.65591684434968	0.457737563193523	0.726218249297417
GO:0030295	protein kinase activator activity	4/469	139/18639	0.0287769784172662	1.14365479897532	0.464593445040656	0.735327754740607
GO:0003707	nuclear steroid receptor activity	1/469	25/18639	0.04	1.58968017057569	0.471399721821632	0.737129335857322
GO:0005537	D-mannose binding	1/469	25/18639	0.04	1.58968017057569	0.471399721821632	0.737129335857322
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/469	25/18639	0.04	1.58968017057569	0.471399721821632	0.737129335857322
GO:0042974	nuclear retinoic acid receptor binding	1/469	25/18639	0.04	1.58968017057569	0.471399721821632	0.737129335857322
GO:0001664	G protein-coupled receptor binding	8/469	297/18639	0.0269360269360269	1.07049169735737	0.472849384865384	0.737129335857322
GO:0008238	exopeptidase activity	3/469	102/18639	0.0294117647058824	1.16888247836448	0.475347688826106	0.737129335857322
GO:0020037	heme binding	4/469	142/18639	0.028169014084507	1.11949307787021	0.481054438256621	0.737129335857322
GO:0004536	DNA nuclease activity	2/469	64/18639	0.03125	1.24193763326226	0.481248527854973	0.737129335857322
GO:0004529	DNA exonuclease activity	1/469	26/18639	0.0384615384615385	1.52853862555355	0.484718381457694	0.737129335857322
GO:0005160	transforming growth factor beta receptor binding	1/469	26/18639	0.0384615384615385	1.52853862555355	0.484718381457694	0.737129335857322
GO:0008143	poly(A) binding	1/469	26/18639	0.0384615384615385	1.52853862555355	0.484718381457694	0.737129335857322
GO:0008198	ferrous iron binding	1/469	26/18639	0.0384615384615385	1.52853862555355	0.484718381457694	0.737129335857322
GO:0015216	purine nucleotide transmembrane transporter activity	1/469	26/18639	0.0384615384615385	1.52853862555355	0.484718381457694	0.737129335857322
GO:0019865	immunoglobulin binding	1/469	26/18639	0.0384615384615385	1.52853862555355	0.484718381457694	0.737129335857322
GO:0034237	protein kinase A regulatory subunit binding	1/469	26/18639	0.0384615384615385	1.52853862555355	0.484718381457694	0.737129335857322
GO:0052742	phosphatidylinositol kinase activity	1/469	26/18639	0.0384615384615385	1.52853862555355	0.484718381457694	0.737129335857322
GO:0120014	phospholipid transfer activity	1/469	26/18639	0.0384615384615385	1.52853862555355	0.484718381457694	0.737129335857322
GO:0035255	ionotropic glutamate receptor binding	1/469	27/18639	0.037037037037037	1.47192608386638	0.497702160488282	0.75513431246498
GO:1901981	phosphatidylinositol phosphate binding	5/469	185/18639	0.027027027027027	1.07410822336195	0.499192732181148	0.755658723026508
GO:0008013	beta-catenin binding	3/469	106/18639	0.0283018867924528	1.12477370559601	0.500866272511381	0.756457070612154
GO:0046966	nuclear thyroid hormone receptor binding	1/469	28/18639	0.0357142857142857	1.41935729515687	0.510359461516167	0.767283017313599
GO:0051393	alpha-actinin binding	1/469	28/18639	0.0357142857142857	1.41935729515687	0.510359461516167	0.767283017313599
GO:0004181	metallocarboxypeptidase activity	1/469	29/18639	0.0344827586206897	1.37041394015146	0.522698476751722	0.784047715127583
GO:1902936	phosphatidylinositol bisphosphate binding	3/469	111/18639	0.027027027027027	1.07410822336195	0.531849522040973	0.789530084022683
GO:0046906	tetrapyrrole binding	4/469	152/18639	0.0263157894736842	1.04584221748401	0.534364286892653	0.789530084022683
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/469	30/18639	0.0333333333333333	1.32473347547974	0.534727193269908	0.789530084022683
GO:0015215	nucleotide transmembrane transporter activity	1/469	30/18639	0.0333333333333333	1.32473347547974	0.534727193269908	0.789530084022683
GO:0016769	transferase activity, transferring nitrogenous groups	1/469	30/18639	0.0333333333333333	1.32473347547974	0.534727193269908	0.789530084022683
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/469	30/18639	0.0333333333333333	1.32473347547974	0.534727193269908	0.789530084022683
GO:0098918	structural constituent of synapse	1/469	30/18639	0.0333333333333333	1.32473347547974	0.534727193269908	0.789530084022683
GO:0051020	GTPase binding	8/469	315/18639	0.0253968253968254	1.00932074322266	0.539440999719306	0.794712187086478
GO:0047499	calcium-independent phospholipase A2 activity	1/469	31/18639	0.032258064516129	1.28200013756104	0.546453398136178	0.803249983897277
GO:0030515	snoRNA binding	1/469	32/18639	0.03125	1.24193763326226	0.557884683404564	0.811021786447164
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/469	32/18639	0.03125	1.24193763326226	0.557884683404564	0.811021786447164
GO:0047498	calcium-dependent phospholipase A2 activity	1/469	32/18639	0.03125	1.24193763326226	0.557884683404564	0.811021786447164
GO:0070717	poly-purine tract binding	1/469	32/18639	0.03125	1.24193763326226	0.557884683404564	0.811021786447164
GO:0140142	nucleocytoplasmic carrier activity	1/469	32/18639	0.03125	1.24193763326226	0.557884683404564	0.811021786447164
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/469	33/18639	0.0303030303030303	1.20430315952704	0.569028450991132	0.821791636004698
GO:0019956	chemokine binding	1/469	33/18639	0.0303030303030303	1.20430315952704	0.569028450991132	0.821791636004698
GO:0030296	protein tyrosine kinase activator activity	1/469	33/18639	0.0303030303030303	1.20430315952704	0.569028450991132	0.821791636004698
GO:0030332	cyclin binding	1/469	34/18639	0.0294117647058824	1.16888247836448	0.579891917425892	0.834965932995057
GO:0051540	metal cluster binding	2/469	77/18639	0.025974025974026	1.03225985102318	0.580680853401108	0.834965932995057
GO:0008083	growth factor activity	4/469	162/18639	0.0246913580246914	0.981284055910921	0.584811332227437	0.839077128848062
GO:0019199	transmembrane receptor protein kinase activity	2/469	78/18639	0.0256410256410256	1.01902575036903	0.587724117499535	0.839909909915733
GO:0000175	3'-5'-RNA exonuclease activity	1/469	35/18639	0.0285714285714286	1.13548583612549	0.590482118486213	0.839909909915733
GO:0004623	phospholipase A2 activity	1/469	35/18639	0.0285714285714286	1.13548583612549	0.590482118486213	0.839909909915733
GO:0016229	steroid dehydrogenase activity	1/469	35/18639	0.0285714285714286	1.13548583612549	0.590482118486213	0.839909909915733
GO:0042393	histone binding	6/469	247/18639	0.0242914979757085	0.965392816139085	0.591859016844694	0.840057959392469
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/469	122/18639	0.0245901639344262	0.977262399944074	0.596008882937307	0.841893637052384
GO:0005516	calmodulin binding	5/469	207/18639	0.0241545893719807	0.959951793825902	0.599024310996818	0.841893637052384
GO:0004033	aldo-keto reductase (NADPH) activity	1/469	36/18639	0.0277777777777778	1.10394456289979	0.600805913714656	0.841893637052384
GO:0004190	aspartic-type endopeptidase activity	1/469	36/18639	0.0277777777777778	1.10394456289979	0.600805913714656	0.841893637052384
GO:0005484	SNAP receptor activity	1/469	36/18639	0.0277777777777778	1.10394456289979	0.600805913714656	0.841893637052384
GO:0045505	dynein intermediate chain binding	1/469	36/18639	0.0277777777777778	1.10394456289979	0.600805913714656	0.841893637052384
GO:0030971	receptor tyrosine kinase binding	2/469	81/18639	0.0246913580246914	0.981284055910921	0.608325569631492	0.848787776724076
GO:0030280	structural constituent of skin epidermis	1/469	37/18639	0.027027027027027	1.07410822336195	0.610869990824145	0.848787776724076
GO:0042805	actinin binding	1/469	37/18639	0.027027027027027	1.07410822336195	0.610869990824145	0.848787776724076
GO:0070001	aspartic-type peptidase activity	1/469	37/18639	0.027027027027027	1.07410822336195	0.610869990824145	0.848787776724076
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/469	38/18639	0.0263157894736842	1.04584221748401	0.620680869993239	0.8588037194875
GO:0043531	ADP binding	1/469	38/18639	0.0263157894736842	1.04584221748401	0.620680869993239	0.8588037194875
GO:0042826	histone deacetylase binding	3/469	127/18639	0.0236220472440945	0.93878750230848	0.62321239704486	0.860502472907129
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	3/469	128/18639	0.0234375	0.931453224946695	0.628500588400717	0.864989917419691
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/469	39/18639	0.0256410256410256	1.01902575036903	0.630244908054266	0.864989917419691
GO:0035591	signaling adaptor activity	3/469	129/18639	0.0232558139534884	0.924232657311449	0.633737480092789	0.864989917419691
GO:0016798	hydrolase activity, acting on glycosyl bonds	3/469	130/18639	0.0230769230769231	0.917123175332131	0.638922924481748	0.864989917419691
GO:0004177	aminopeptidase activity	1/469	40/18639	0.025	0.993550106609808	0.639568302576984	0.864989917419691
GO:0004532	RNA exonuclease activity	1/469	40/18639	0.025	0.993550106609808	0.639568302576984	0.864989917419691
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/469	40/18639	0.025	0.993550106609808	0.639568302576984	0.864989917419691
GO:0061791	GTPase motor activity	1/469	40/18639	0.025	0.993550106609808	0.639568302576984	0.864989917419691
GO:0071949	FAD binding	1/469	40/18639	0.025	0.993550106609808	0.639568302576984	0.864989917419691
GO:1990606	membrane scission GTPase motor activity	1/469	40/18639	0.025	0.993550106609808	0.639568302576984	0.864989917419691
GO:0008081	phosphoric diester hydrolase activity	2/469	87/18639	0.0229885057471264	0.913609293434306	0.647158479293322	0.86551866666841
GO:0001727	lipid kinase activity	1/469	41/18639	0.024390243902439	0.969317177180301	0.648657095850353	0.86551866666841
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	1/469	41/18639	0.024390243902439	0.969317177180301	0.648657095850353	0.86551866666841
GO:0017080	sodium channel regulator activity	1/469	41/18639	0.024390243902439	0.969317177180301	0.648657095850353	0.86551866666841
GO:0042169	SH2 domain binding	1/469	41/18639	0.024390243902439	0.969317177180301	0.648657095850353	0.86551866666841
GO:0005179	hormone activity	3/469	132/18639	0.0227272727272727	0.90322736964528	0.649139000001307	0.86551866666841
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	3/469	132/18639	0.0227272727272727	0.90322736964528	0.649139000001307	0.86551866666841
GO:0004520	DNA endonuclease activity	1/469	42/18639	0.0238095238095238	0.946238196771246	0.657517178764977	0.869261478815655
GO:0019894	kinesin binding	1/469	42/18639	0.0238095238095238	0.946238196771246	0.657517178764977	0.869261478815655
GO:0031492	nucleosomal DNA binding	1/469	42/18639	0.0238095238095238	0.946238196771246	0.657517178764977	0.869261478815655
GO:0051879	Hsp90 protein binding	1/469	42/18639	0.0238095238095238	0.946238196771246	0.657517178764977	0.869261478815655
GO:0005319	lipid transporter activity	4/469	178/18639	0.0224719101123595	0.893078747514434	0.658531423345193	0.869261478815655
GO:0008375	acetylglucosaminyltransferase activity	1/469	43/18639	0.0232558139534884	0.924232657311449	0.666154294598672	0.877568531806634
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	2/469	91/18639	0.021978021978022	0.873450643173458	0.671313180967413	0.882602986929267
GO:0001046	core promoter sequence-specific DNA binding	1/469	44/18639	0.0227272727272727	0.90322736964528	0.674574042707579	0.883370770212306
GO:0043014	alpha-tubulin binding	1/469	44/18639	0.0227272727272727	0.90322736964528	0.674574042707579	0.883370770212306
GO:0045182	translation regulator activity	8/469	356/18639	0.0224719101123595	0.893078747514434	0.676315790464593	0.883897864765606
GO:0046915	transition metal ion transmembrane transporter activity	1/469	45/18639	0.0222222222222222	0.883155650319829	0.682781882125172	0.888956138458416
GO:0051219	phosphoprotein binding	2/469	93/18639	0.021505376344086	0.854666758374029	0.682879942724875	0.888956138458416
GO:0000287	magnesium ion binding	5/469	230/18639	0.0217391304347826	0.863956614443311	0.690318235339409	0.892205223379969
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/469	46/18639	0.0217391304347826	0.863956614443311	0.690783135071461	0.892205223379969
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/469	46/18639	0.0217391304347826	0.863956614443311	0.690783135071461	0.892205223379969
GO:0030276	clathrin binding	1/469	46/18639	0.0217391304347826	0.863956614443311	0.690783135071461	0.892205223379969
GO:0001784	phosphotyrosine residue binding	1/469	47/18639	0.0212765957446809	0.845574558816858	0.698582990374612	0.895389898828495
GO:0140597	protein carrier chaperone	4/469	188/18639	0.0212765957446809	0.845574558816858	0.69988190939955	0.895389898828495
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/469	48/18639	0.0208333333333333	0.82795842217484	0.70618650680718	0.895389898828495
GO:0140693	molecular condensate scaffold activity	1/469	48/18639	0.0208333333333333	0.82795842217484	0.70618650680718	0.895389898828495
GO:0005004	GPI-linked ephrin receptor activity	1/469	49/18639	0.0204081632653061	0.811061311518211	0.713598616339073	0.895389898828495
GO:0005008	hepatocyte growth factor receptor activity	1/469	49/18639	0.0204081632653061	0.811061311518211	0.713598616339073	0.895389898828495
GO:0005009	insulin receptor activity	1/469	49/18639	0.0204081632653061	0.811061311518211	0.713598616339073	0.895389898828495
GO:0005011	macrophage colony-stimulating factor receptor activity	1/469	49/18639	0.0204081632653061	0.811061311518211	0.713598616339073	0.895389898828495
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/469	49/18639	0.0204081632653061	0.811061311518211	0.713598616339073	0.895389898828495
GO:0005020	stem cell factor receptor activity	1/469	49/18639	0.0204081632653061	0.811061311518211	0.713598616339073	0.895389898828495
GO:0008288	boss receptor activity	1/469	49/18639	0.0204081632653061	0.811061311518211	0.713598616339073	0.895389898828495
GO:0035254	glutamate receptor binding	1/469	49/18639	0.0204081632653061	0.811061311518211	0.713598616339073	0.895389898828495
GO:0036332	placental growth factor receptor activity	1/469	49/18639	0.0204081632653061	0.811061311518211	0.713598616339073	0.895389898828495
GO:0038062	protein tyrosine kinase collagen receptor activity	1/469	49/18639	0.0204081632653061	0.811061311518211	0.713598616339073	0.895389898828495
GO:0060175	brain-derived neurotrophic factor receptor activity	1/469	49/18639	0.0204081632653061	0.811061311518211	0.713598616339073	0.895389898828495
GO:0005006	epidermal growth factor receptor activity	1/469	50/18639	0.02	0.794840085287847	0.720824127309325	0.895939593265828
GO:0005007	fibroblast growth factor receptor activity	1/469	50/18639	0.02	0.794840085287847	0.720824127309325	0.895939593265828
GO:0005017	platelet-derived growth factor receptor activity	1/469	50/18639	0.02	0.794840085287847	0.720824127309325	0.895939593265828
GO:0005019	platelet-derived growth factor beta-receptor activity	1/469	50/18639	0.02	0.794840085287847	0.720824127309325	0.895939593265828
GO:0015605	organophosphate ester transmembrane transporter activity	1/469	50/18639	0.02	0.794840085287847	0.720824127309325	0.895939593265828
GO:0035091	phosphatidylinositol binding	6/469	284/18639	0.0211267605633803	0.839619808402655	0.722915722723952	0.896850332702647
GO:0005010	insulin-like growth factor receptor activity	1/469	51/18639	0.0196078431372549	0.77925498557632	0.727867727518692	0.897930280677265
GO:0005021	vascular endothelial growth factor receptor activity	1/469	51/18639	0.0196078431372549	0.77925498557632	0.727867727518692	0.897930280677265
GO:0005030	neurotrophin receptor activity	1/469	51/18639	0.0196078431372549	0.77925498557632	0.727867727518692	0.897930280677265
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/469	52/18639	0.0192307692307692	0.764269312776776	0.73473398724506	0.903025012256499
GO:0030159	signaling receptor complex adaptor activity	1/469	52/18639	0.0192307692307692	0.764269312776776	0.73473398724506	0.903025012256499
GO:0005003	ephrin receptor activity	1/469	53/18639	0.0188679245283019	0.749849137064006	0.741427362183569	0.904513972349641
GO:0005005	transmembrane-ephrin receptor activity	1/469	53/18639	0.0188679245283019	0.749849137064006	0.741427362183569	0.904513972349641
GO:0038064	collagen receptor activity	1/469	53/18639	0.0188679245283019	0.749849137064006	0.741427362183569	0.904513972349641
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/469	53/18639	0.0188679245283019	0.749849137064006	0.741427362183569	0.904513972349641
GO:0017069	snRNA binding	1/469	54/18639	0.0185185185185185	0.735963041933191	0.747952196313339	0.910790497355727
GO:0000149	SNARE binding	2/469	106/18639	0.0188679245283019	0.749849137064006	0.750124751496466	0.911753841597914
GO:0008374	O-acyltransferase activity	1/469	55/18639	0.0181818181818182	0.722581895716224	0.754312724692626	0.915158820399142
GO:0003714	transcription corepressor activity	4/469	204/18639	0.0196078431372549	0.77925498557632	0.758324530976454	0.918337964118275
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/469	57/18639	0.0175438596491228	0.697228144989339	0.766557276112595	0.92660769639984
GO:0008408	3'-5' exonuclease activity	1/469	58/18639	0.0172413793103448	0.68520697007573	0.772449248855206	0.932022859679042
GO:0036002	pre-mRNA binding	1/469	59/18639	0.0169491525423729	0.673593292616819	0.778192820368413	0.933759089584016
GO:0001098	basal transcription machinery binding	1/469	60/18639	0.0166666666666667	0.662366737739872	0.783791720650825	0.933759089584016
GO:0001099	basal RNA polymerase II transcription machinery binding	1/469	60/18639	0.0166666666666667	0.662366737739872	0.783791720650825	0.933759089584016
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/469	60/18639	0.0166666666666667	0.662366737739872	0.783791720650825	0.933759089584016
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/469	60/18639	0.0166666666666667	0.662366737739872	0.783791720650825	0.933759089584016
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	1/469	60/18639	0.0166666666666667	0.662366737739872	0.783791720650825	0.933759089584016
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/469	60/18639	0.0166666666666667	0.662366737739872	0.783791720650825	0.933759089584016
GO:0035401	histone H3Y41 kinase activity	2/469	115/18639	0.0173913043478261	0.691165291554649	0.789178650971999	0.936794801513524
GO:0140801	histone H2AXY142 kinase activity	2/469	115/18639	0.0173913043478261	0.691165291554649	0.789178650971999	0.936794801513524
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	5/469	268/18639	0.0186567164179104	0.741455303440155	0.807840914549628	0.956256226430312
GO:0032182	ubiquitin-like protein binding	2/469	120/18639	0.0166666666666667	0.662366737739872	0.808471173254718	0.956256226430312
GO:0004540	RNA nuclease activity	2/469	121/18639	0.0165289256198347	0.656892632469295	0.812135942067203	0.958872489739453
GO:0008235	metalloexopeptidase activity	1/469	66/18639	0.0151515151515152	0.60215157976352	0.8145444085381	0.959691834963963
GO:0008528	G protein-coupled peptide receptor activity	2/469	122/18639	0.0163934426229508	0.651508266629382	0.815738059719368	0.959691834963963
GO:0016500	protein-hormone receptor activity	1/469	67/18639	0.0149253731343284	0.593164242752124	0.81922747925342	0.962082093073411
GO:0005548	phospholipid transporter activity	1/469	68/18639	0.0147058823529412	0.58444123918224	0.823792540217783	0.964012547063363
GO:1990841	promoter-specific chromatin binding	1/469	68/18639	0.0147058823529412	0.58444123918224	0.823792540217783	0.964012547063363
GO:0002039	p53 binding	1/469	69/18639	0.0144927536231884	0.575971076295541	0.828242558991024	0.967239789874829
GO:0001217	DNA-binding transcription repressor activity	5/469	278/18639	0.0179856115107914	0.714784249359574	0.832078223130328	0.967239789874829
GO:0004519	endonuclease activity	2/469	127/18639	0.015748031496063	0.62585833487232	0.832837661241062	0.967239789874829
GO:0019783	ubiquitin-like protein peptidase activity	2/469	127/18639	0.015748031496063	0.62585833487232	0.832837661241062	0.967239789874829
GO:0005085	guanyl-nucleotide exchange factor activity	4/469	230/18639	0.0173913043478261	0.691165291554649	0.833987685163868	0.967239789874829
GO:0001653	peptide receptor activity	2/469	128/18639	0.015625	0.62096881663113	0.836081106841702	0.967239789874829
GO:0140299	molecular sensor activity	1/469	71/18639	0.0140845070422535	0.559746538935103	0.836808969725041	0.967239789874829
GO:0004521	RNA endonuclease activity	1/469	73/18639	0.0136986301369863	0.544411017320443	0.844948995802893	0.972658700421774
GO:0043539	protein serine/threonine kinase activator activity	1/469	73/18639	0.0136986301369863	0.544411017320443	0.844948995802893	0.972658700421774
GO:0003684	damaged DNA binding	1/469	74/18639	0.0135135135135135	0.537054111680977	0.848865774913549	0.972658700421774
GO:0031491	nucleosome binding	1/469	74/18639	0.0135135135135135	0.537054111680977	0.848865774913549	0.972658700421774
GO:0048029	monosaccharide binding	1/469	74/18639	0.0135135135135135	0.537054111680977	0.848865774913549	0.972658700421774
GO:0019003	GDP binding	1/469	75/18639	0.0133333333333333	0.529893390191898	0.85268381701242	0.975340241296702
GO:0051536	iron-sulfur cluster binding	1/469	76/18639	0.0131578947368421	0.522921108742004	0.856405605949135	0.977902595028424
GO:0003724	RNA helicase activity	1/469	77/18639	0.012987012987013	0.516129925511589	0.860033563219504	0.980349139421196
GO:0008186	ATP-dependent activity, acting on RNA	1/469	79/18639	0.0126582278481013	0.50306334511889	0.867017366308525	0.984529494789604
GO:0070851	growth factor receptor binding	2/469	139/18639	0.0143884892086331	0.571827399487659	0.868176009041742	0.984529494789604
GO:0140767	enzyme-substrate adaptor activity	2/469	139/18639	0.0143884892086331	0.571827399487659	0.868176009041742	0.984529494789604
GO:0004713	protein tyrosine kinase activity	2/469	140/18639	0.0142857142857143	0.567742918062747	0.870788247724366	0.985798016291735
GO:0005254	chloride channel activity	1/469	83/18639	0.0120481927710843	0.478819328486655	0.879958974581545	0.994474183602431
GO:0004527	exonuclease activity	1/469	84/18639	0.0119047619047619	0.473119098385623	0.882992992738543	0.996197222576818
GO:0050660	flavin adenine dinucleotide binding	1/469	86/18639	0.0116279069767442	0.462116328655725	0.888833380310238	0.999990926457047
GO:0008168	methyltransferase activity	3/469	204/18639	0.0147058823529412	0.58444123918224	0.890518037912286	0.999990926457047
GO:0019842	vitamin binding	2/469	150/18639	0.0133333333333333	0.529893390191898	0.894410384516852	0.999990926457047
GO:0004518	nuclease activity	3/469	209/18639	0.0143540669856459	0.570459391354914	0.899790041694157	0.999990926457047
GO:0005506	iron ion binding	2/469	154/18639	0.012987012987013	0.516129925511589	0.902684244275437	0.999990926457047
GO:0052689	carboxylic ester hydrolase activity	1/469	92/18639	0.0108695652173913	0.431978307221656	0.904666087976631	0.999990926457047
GO:0051213	dioxygenase activity	1/469	93/18639	0.010752688172043	0.427333379187014	0.907076806946759	0.999990926457047
GO:0016410	N-acyltransferase activity	1/469	94/18639	0.0106382978723404	0.422787279408429	0.909426692503858	0.999990926457047
GO:0016741	transferase activity, transferring one-carbon groups	3/469	215/18639	0.013953488372093	0.55453959438687	0.909979945524235	0.999990926457047
GO:0008170	N-methyltransferase activity	1/469	98/18639	0.0102040816326531	0.405530655759105	0.918247967058801	0.999990926457047
GO:0042626	ATPase-coupled transmembrane transporter activity	1/469	98/18639	0.0102040816326531	0.405530655759105	0.918247967058801	0.999990926457047
GO:0140713	histone chaperone activity	2/469	164/18639	0.0121951219512195	0.48465858859015	0.920796594563935	0.999990926457047
GO:0043130	ubiquitin binding	1/469	100/18639	0.01	0.397420042643923	0.922331649604182	0.999990926457047
GO:0015103	inorganic anion transmembrane transporter activity	2/469	165/18639	0.0121212121212121	0.481721263810816	0.922422332336419	0.999990926457047
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	8/469	484/18639	0.0165289256198347	0.656892632469295	0.923352764494345	0.999990926457047
GO:0015631	tubulin binding	6/469	385/18639	0.0155844155844156	0.619355910613906	0.924845674240795	0.999990926457047
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/469	167/18639	0.0119760479041916	0.47595214687895	0.925580053432893	0.999990926457047
GO:0005253	monoatomic anion channel activity	1/469	103/18639	0.00970873786407767	0.385844701596042	0.928078654861153	0.999990926457047
GO:0031267	small GTPase binding	4/469	283/18639	0.0141342756183746	0.561724441899538	0.928349407914237	0.999990926457047
GO:0001216	DNA-binding transcription activator activity	8/469	491/18639	0.0162932790224033	0.647527564389284	0.930036823605378	0.999990926457047
GO:0005261	monoatomic cation channel activity	5/469	341/18639	0.0146627565982405	0.582727335255019	0.933313283642066	0.999990926457047
GO:0004497	monooxygenase activity	1/469	106/18639	0.00943396226415094	0.374924568532003	0.933401254603692	0.999990926457047
GO:0004843	cysteine-type deubiquitinase activity	1/469	108/18639	0.00925925925925926	0.367981520966596	0.936729416869042	0.999990926457047
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	2/469	181/18639	0.0110497237569061	0.439138168667319	0.944513977691545	0.999990926457047
GO:0017124	SH3 domain binding	1/469	115/18639	0.00869565217391304	0.345582645777325	0.947124081092781	0.999990926457047
GO:0101005	deubiquitinase activity	1/469	115/18639	0.00869565217391304	0.345582645777325	0.947124081092781	0.999990926457047
GO:0015294	solute:monoatomic cation symporter activity	1/469	116/18639	0.00862068965517241	0.342603485037865	0.948462820348206	0.999990926457047
GO:0015108	chloride transmembrane transporter activity	1/469	121/18639	0.00826446280991736	0.328446316234647	0.954665887970601	0.999990926457047
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	1/469	122/18639	0.00819672131147541	0.325754133314691	0.955814051840446	0.999990926457047
GO:0016758	hexosyltransferase activity	2/469	197/18639	0.0101522842639594	0.403472124511597	0.960539103243564	0.999990926457047
GO:0031490	chromatin DNA binding	1/469	128/18639	0.0078125	0.310484408315565	0.962118621975598	0.999990926457047
GO:0016757	glycosyltransferase activity	3/469	267/18639	0.0112359550561798	0.446539373757217	0.965906147724257	0.999990926457047
GO:0015297	antiporter activity	1/469	135/18639	0.00740740740740741	0.294385216773276	0.968348336325971	0.999990926457047
GO:0016779	nucleotidyltransferase activity	1/469	136/18639	0.00735294117647059	0.29222061959112	0.969150575315547	0.999990926457047
GO:0005216	monoatomic ion channel activity	6/469	448/18639	0.0133928571428571	0.532258985683826	0.971077977623572	0.999990926457047
GO:0008017	microtubule binding	3/469	276/18639	0.0108695652173913	0.431978307221656	0.971368372567386	0.999990926457047
GO:0008194	UDP-glycosyltransferase activity	1/469	145/18639	0.00689655172413793	0.274082788030292	0.975516452960087	0.999990926457047
GO:0015293	symporter activity	1/469	146/18639	0.00684931506849315	0.272205508660221	0.976137345333923	0.999990926457047
GO:0008509	monoatomic anion transmembrane transporter activity	1/469	149/18639	0.00671140939597315	0.266724860834848	0.977907322647889	0.999990926457047
GO:0000510	H3-H4 histone complex chaperone activity	1/469	151/18639	0.00662251655629139	0.263192081221141	0.979013902330553	0.999990926457047
GO:0140584	chromatin extrusion motor activity	1/469	151/18639	0.00662251655629139	0.263192081221141	0.979013902330553	0.999990926457047
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	1/469	151/18639	0.00662251655629139	0.263192081221141	0.979013902330553	0.999990926457047
GO:0140849	ATP-dependent H2AZ histone chaperone activity	1/469	151/18639	0.00662251655629139	0.263192081221141	0.979013902330553	0.999990926457047
GO:0015616	DNA translocase activity	1/469	152/18639	0.00657894736842105	0.261460554371002	0.979546273587962	0.999990926457047
GO:0140674	ATP-dependent histone chaperone activity	1/469	152/18639	0.00657894736842105	0.261460554371002	0.979546273587962	0.999990926457047
GO:0003774	cytoskeletal motor activity	1/469	153/18639	0.0065359477124183	0.259751661858773	0.980065167821058	0.999990926457047
GO:0061775	cohesin loader activity	1/469	153/18639	0.0065359477124183	0.259751661858773	0.980065167821058	0.999990926457047
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	2/469	229/18639	0.00873362445414847	0.34709174030037	0.980325742735373	0.999990926457047
GO:0016887	ATP hydrolysis activity	5/469	417/18639	0.0119904076738609	0.476522832906383	0.980914425556816	0.999990926457047
GO:0004386	helicase activity	1/469	155/18639	0.00645161290322581	0.256400027512209	0.981063878477203	0.999990926457047
GO:0140658	ATP-dependent chromatin remodeler activity	1/469	158/18639	0.00632911392405063	0.251531672559445	0.982469103867331	0.999990926457047
GO:0042578	phosphoric ester hydrolase activity	4/469	363/18639	0.0110192837465565	0.437928421646196	0.982527382927058	0.999990926457047
GO:0003689	DNA clamp loader activity	1/469	160/18639	0.00625	0.248387526652452	0.983347614842816	0.999990926457047
GO:0030695	GTPase regulator activity	6/469	489/18639	0.0122699386503067	0.487631954164323	0.985150122129366	0.999990926457047
GO:0060589	nucleoside-triphosphatase regulator activity	6/469	490/18639	0.0122448979591837	0.486636786910926	0.985395376365906	0.999990926457047
GO:0004721	phosphoprotein phosphatase activity	1/469	175/18639	0.00571428571428571	0.227097167225099	0.988677538268902	0.999990926457047
GO:0140098	catalytic activity, acting on RNA	4/469	387/18639	0.0103359173126615	0.4107700699162	0.988850237673732	0.999990926457047
GO:0140097	catalytic activity, acting on DNA	3/469	336/18639	0.00892857142857143	0.354839323789217	0.991405029396753	0.999990926457047
GO:0005096	GTPase activator activity	2/469	271/18639	0.00738007380073801	0.29329892446046	0.992291864415137	0.999990926457047
GO:0016791	phosphatase activity	2/469	273/18639	0.00732600732600733	0.291150214391153	0.992632409098532	0.999990926457047
GO:0015291	secondary active transmembrane transporter activity	2/469	287/18639	0.00696864111498258	0.276947764908657	0.994637077775891	0.999990926457047
GO:0008094	ATP-dependent activity, acting on DNA	1/469	210/18639	0.00476190476190476	0.189247639354249	0.995402859971508	0.999990926457047
GO:0030371	translation repressor activity	2/469	329/18639	0.0060790273556231	0.241592731090531	0.997956677191787	0.999990926457047
GO:0035402	histone H3T11 kinase activity	1/469	247/18639	0.00404858299595142	0.160898802689847	0.998230518037899	0.999990926457047
GO:0061630	ubiquitin protein ligase activity	2/469	353/18639	0.0056657223796034	0.225167162971061	0.998831199318344	0.999990926457047
GO:0141003	histone H2AX kinase activity	2/469	354/18639	0.00564971751412429	0.22453109753894	0.998858206235678	0.999990926457047
GO:0140996	histone H3 kinase activity	2/469	357/18639	0.00560224089635854	0.222644281593234	0.998935590538882	0.999990926457047
GO:0008514	organic anion transmembrane transporter activity	1/469	269/18639	0.00371747211895911	0.147739792804432	0.998997921565159	0.999990926457047
GO:0035173	histone kinase activity	2/469	360/18639	0.00555555555555556	0.220788912579957	0.999007800002942	0.999990926457047
GO:0061659	ubiquitin-like protein ligase activity	2/469	372/18639	0.00537634408602151	0.213666689593507	0.999251377494502	0.999990926457047
GO:0016755	aminoacyltransferase activity	3/469	496/18639	0.00604838709677419	0.240375025792696	0.999726469452464	0.999990926457047
GO:0004674	protein serine/threonine kinase activity	2/469	433/18639	0.0046189376443418	0.183565839558394	0.999823935828859	0.999990926457047
GO:0004842	ubiquitin-protein transferase activity	2/469	449/18639	0.0044543429844098	0.17702451788148	0.999880016850145	0.999990926457047
GO:0019787	ubiquitin-like protein transferase activity	2/469	479/18639	0.00417536534446764	0.165937387325229	0.999941767485014	0.999990926457047
GO:0046873	metal ion transmembrane transporter activity	1/469	450/18639	0.00222222222222222	0.0883155650319829	0.999990926457047	0.999990926457047