ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	102/2200	175/18639	0.582857142857143	4.93812467532468	1.18712949672644e-49	1.43880095003245e-46
GO:0019843	rRNA binding	30/2200	65/18639	0.461538461538462	3.91027972027972	5.56284776901501e-12	3.37108574802309e-09
GO:0005201	extracellular matrix structural constituent	49/2200	168/18639	0.291666666666667	2.47107954545455	9.50771568610287e-10	3.84111713718556e-07
GO:0005518	collagen binding	27/2200	72/18639	0.375	3.17710227272727	1.68963784007315e-08	5.11960265542163e-06
GO:0019838	growth factor binding	39/2200	136/18639	0.286764705882353	2.42954879679144	7.87668851323023e-08	1.90930929560701e-05
GO:0050840	extracellular matrix binding	23/2200	67/18639	0.343283582089552	2.9083921302578	1.1906132873437e-06	0.000240503884043428
GO:0003713	transcription coactivator activity	57/2200	256/18639	0.22265625	1.88640447443182	1.43967992886742e-06	0.00024927029625533
GO:0003712	transcription coregulator activity	94/2200	495/18639	0.18989898989899	1.60887603305785	1.79659095820571e-06	0.000272183530168165
GO:0043021	ribonucleoprotein complex binding	42/2200	177/18639	0.23728813559322	2.01036979969183	6.42161856109191e-06	0.000864777966227044
GO:0140297	DNA-binding transcription factor binding	90/2200	488/18639	0.184426229508197	1.56250931445604	1.00205542640782e-05	0.00111701228444405
GO:0003714	transcription corepressor activity	46/2200	204/18639	0.225490196078431	1.91041443850267	1.01379002713569e-05	0.00111701228444405
GO:0140104	molecular carrier activity	52/2200	249/18639	0.208835341365462	1.76930996714129	2.72063376720935e-05	0.00274784010488145
GO:0048027	mRNA 5'-UTR binding	11/2200	24/18639	0.458333333333333	3.883125	3.46466107046115e-05	0.00323013016722994
GO:0032977	membrane insertase activity	9/2200	17/18639	0.529411764705882	4.48532085561497	4.37041567805281e-05	0.003783531287
GO:0019211	phosphatase activator activity	11/2200	25/18639	0.44	3.7278	5.52808203045207e-05	0.00446669028060527
GO:0031625	ubiquitin protein ligase binding	59/2200	302/18639	0.195364238410596	1.6551791089705	6.31243936021787e-05	0.00455842935028104
GO:0140597	protein carrier chaperone	41/2200	188/18639	0.218085106382979	1.84767649903288	6.7319433734431e-05	0.00455842935028104
GO:1990948	ubiquitin ligase inhibitor activity	7/2200	11/18639	0.636363636363636	5.39144628099174	6.76994457962531e-05	0.00455842935028104
GO:0001968	fibronectin binding	12/2200	30/18639	0.4	3.38890909090909	7.91101404410871e-05	0.00504639422182093
GO:0045296	cadherin binding	63/2200	334/18639	0.188622754491018	1.59806341861731	0.000105838560350585	0.00641381675724545
GO:0044389	ubiquitin-like protein ligase binding	61/2200	322/18639	0.18944099378882	1.60499576510446	0.000119204986141951	0.00687983062876404
GO:0055106	ubiquitin-protein transferase regulator activity	13/2200	36/18639	0.361111111111111	3.05943181818182	0.000138578162675271	0.00763439696192859
GO:0031994	insulin-like growth factor I binding	7/2200	13/18639	0.538461538461538	4.56199300699301	0.000283798500358952	0.0149549470623934
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	63/2200	349/18639	0.180515759312321	1.5293787444647	0.000372782708331125	0.0188255267707218
GO:0043022	ribosome binding	26/2200	112/18639	0.232142857142857	1.9667775974026	0.000501252405051616	0.0243007165969024
GO:0019903	protein phosphatase binding	31/2200	144/18639	0.215277777777778	1.82389204545455	0.000621283164487197	0.028961353667634
GO:0030515	snoRNA binding	11/2200	32/18639	0.34375	2.91234375	0.000730092048277343	0.0300019148132429
GO:0070990	snRNP binding	6/2200	11/18639	0.545454545454545	4.62123966942149	0.000731381882596932	0.0300019148132429
GO:0019902	phosphatase binding	38/2200	190/18639	0.2	1.69445454545455	0.000747296343004448	0.0300019148132429
GO:0031491	nucleosome binding	19/2200	74/18639	0.256756756756757	2.17531326781327	0.00075570914443275	0.0300019148132429
GO:0001221	transcription coregulator binding	26/2200	115/18639	0.226086956521739	1.91547035573123	0.000767375708919579	0.0300019148132429
GO:0005520	insulin-like growth factor binding	8/2200	19/18639	0.421052631578947	3.56727272727273	0.000843337326668748	0.0315385915829435
GO:0055105	ubiquitin-protein transferase inhibitor activity	7/2200	15/18639	0.466666666666667	3.95372727272727	0.000858724028248461	0.0315385915829435
GO:0019208	phosphatase regulator activity	26/2200	117/18639	0.222222222222222	1.88272727272727	0.0010067199796266	0.0358866063325716
GO:0017069	snRNA binding	15/2200	54/18639	0.277777777777778	2.35340909090909	0.00111224447223138	0.0385154371526982
GO:0043236	laminin binding	10/2200	29/18639	0.344827586206897	2.92147335423198	0.00123175319541554	0.0413089916750289
GO:0031418	L-ascorbic acid binding	8/2200	20/18639	0.4	3.38890909090909	0.00126108307918818	0.0413089916750289
GO:0072542	protein phosphatase activator activity	8/2200	21/18639	0.380952380952381	3.22753246753247	0.0018281059695059	0.0573737816917707
GO:0031490	chromatin DNA binding	27/2200	128/18639	0.2109375	1.78712002840909	0.00184618604453718	0.0573737816917707
GO:0003684	damaged DNA binding	18/2200	74/18639	0.243243243243243	2.0608230958231	0.00199936745451186	0.0605808338717095
GO:0002020	protease binding	28/2200	136/18639	0.205882352941176	1.74429144385027	0.00224259658597483	0.0662933429805243
GO:0070034	telomerase RNA binding	8/2200	22/18639	0.363636363636364	3.08082644628099	0.00257850219866791	0.0744082063044169
GO:0043130	ubiquitin binding	22/2200	100/18639	0.22	1.8639	0.0027066655127057	0.076290200032542
GO:0031369	translation initiation factor binding	10/2200	32/18639	0.3125	2.64758522727273	0.00284926389879062	0.0784842692121417
GO:0019888	protein phosphatase regulator activity	23/2200	107/18639	0.214953271028037	1.8211427357689	0.00300693057727221	0.0808799843423941
GO:0032182	ubiquitin-like protein binding	25/2200	120/18639	0.208333333333333	1.76505681818182	0.00317572482245463	0.0808799843423941
GO:0003724	RNA helicase activity	18/2200	77/18639	0.233766233766234	1.98053128689492	0.00319097534162287	0.0808799843423941
GO:0008135	translation factor activity, RNA binding	19/2200	83/18639	0.228915662650602	1.93943592552026	0.00320316769672848	0.0808799843423941
GO:0097177	mitochondrial ribosome binding	5/2200	10/18639	0.5	4.23613636363636	0.00344174605730368	0.0851305351316747
GO:0180051	translation factor activity	19/2200	84/18639	0.226190476190476	1.9163474025974	0.00369107606505816	0.0894716838170097
GO:0008186	ATP-dependent activity, acting on RNA	18/2200	79/18639	0.227848101265823	1.93039125431531	0.00427454040929073	0.101583195609027
GO:1990782	protein tyrosine kinase binding	24/2200	117/18639	0.205128205128205	1.7379020979021	0.00466410462903215	0.108709515584365
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	16/2200	68/18639	0.235294117647059	1.99347593582888	0.00492041739358255	0.109938630551799
GO:1990841	promoter-specific chromatin binding	16/2200	68/18639	0.235294117647059	1.99347593582888	0.00492041739358255	0.109938630551799
GO:0030246	carbohydrate binding	48/2200	280/18639	0.171428571428571	1.45238961038961	0.00498896425771367	0.109938630551799
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	6/2200	15/18639	0.4	3.38890909090909	0.00521396277351155	0.112845051455286
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	11/2200	40/18639	0.275	2.329875	0.00537906479119281	0.114375903981152
GO:0042608	T cell receptor binding	5/2200	11/18639	0.454545454545455	3.85103305785124	0.00570038286955929	0.116114481778621
GO:0048407	platelet-derived growth factor binding	5/2200	11/18639	0.454545454545455	3.85103305785124	0.00570038286955929	0.116114481778621
GO:0033218	amide binding	43/2200	247/18639	0.174089068825911	1.47493006993007	0.00574824167220895	0.116114481778621
GO:0004709	MAP kinase kinase kinase activity	8/2200	25/18639	0.32	2.71112727272727	0.00631475704009644	0.125466975944211
GO:0001540	amyloid-beta binding	18/2200	83/18639	0.216867469879518	1.83736035049288	0.00735240128184557	0.142298781020225
GO:0005178	integrin binding	30/2200	161/18639	0.186335403726708	1.57868435911914	0.00739671881540772	0.142298781020225
GO:0017070	U6 snRNA binding	6/2200	16/18639	0.375	3.17710227272727	0.00751926472533734	0.142366943926703
GO:0160215	deacylase activity	15/2200	65/18639	0.230769230769231	1.95513986013986	0.00767135575624151	0.142366943926703
GO:0004386	helicase activity	29/2200	155/18639	0.187096774193548	1.5851348973607	0.0078875124233211	0.142366943926703
GO:0031492	nucleosomal DNA binding	11/2200	42/18639	0.261904761904762	2.21892857142857	0.00798758431271931	0.142366943926703
GO:0048487	beta-tubulin binding	11/2200	42/18639	0.261904761904762	2.21892857142857	0.00798758431271931	0.142366943926703
GO:0031543	peptidyl-proline dioxygenase activity	5/2200	12/18639	0.416666666666667	3.53011363636364	0.00883144491205877	0.151767051247722
GO:0097371	MDM2/MDM4 family protein binding	5/2200	12/18639	0.416666666666667	3.53011363636364	0.00883144491205877	0.151767051247722
GO:0019213	deacetylase activity	10/2200	37/18639	0.27027027027027	2.28980343980344	0.00889064409124443	0.151767051247722
GO:1901681	sulfur compound binding	46/2200	275/18639	0.167272727272727	1.41718016528926	0.00920814449921623	0.155003765736806
GO:0042393	histone binding	42/2200	247/18639	0.17004048582996	1.44062937062937	0.00943030052120087	0.156568825091719
GO:0140713	histone chaperone activity	30/2200	164/18639	0.182926829268293	1.54980598669623	0.0096022159015302	0.157268725306143
GO:0140658	ATP-dependent chromatin remodeler activity	29/2200	158/18639	0.183544303797468	1.55503739930955	0.010270202307521	0.165966469289539
GO:0004407	histone deacetylase activity	7/2200	22/18639	0.318181818181818	2.69572314049587	0.0108215688473286	0.168150531320029
GO:0030021	extracellular matrix structural constituent conferring compression resistance	7/2200	22/18639	0.318181818181818	2.69572314049587	0.0108215688473286	0.168150531320029
GO:0033558	protein lysine deacetylase activity	7/2200	22/18639	0.318181818181818	2.69572314049587	0.0108215688473286	0.168150531320029
GO:0140416	transcription regulator inhibitor activity	9/2200	33/18639	0.272727272727273	2.31061983471074	0.0120371723903494	0.184671556165866
GO:0030971	receptor tyrosine kinase binding	17/2200	81/18639	0.209876543209877	1.77813131313131	0.0125159621054228	0.189616825897155
GO:0042826	histone deacetylase binding	24/2200	127/18639	0.188976377952756	1.60105941302792	0.0130381769494329	0.195089758798922
GO:0003743	translation initiation factor activity	12/2200	51/18639	0.235294117647059	1.99347593582888	0.013863560398104	0.199759195747095
GO:0004602	glutathione peroxidase activity	7/2200	23/18639	0.304347826086957	2.57851778656127	0.0140030994593473	0.199759195747095
GO:0003746	translation elongation factor activity	6/2200	18/18639	0.333333333333333	2.82409090909091	0.0141743323714936	0.199759195747095
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	6/2200	18/18639	0.333333333333333	2.82409090909091	0.0141743323714936	0.199759195747095
GO:0070064	proline-rich region binding	6/2200	18/18639	0.333333333333333	2.82409090909091	0.0141743323714936	0.199759195747095
GO:0097110	scaffold protein binding	15/2200	70/18639	0.214285714285714	1.81548701298701	0.0152188650798891	0.212014534216386
GO:0035591	signaling adaptor activity	24/2200	129/18639	0.186046511627907	1.57623678646934	0.0156640225633512	0.214359223161165
GO:0004857	enzyme inhibitor activity	64/2200	416/18639	0.153846153846154	1.30342657342657	0.0158130669431022	0.214359223161165
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	11/2200	46/18639	0.239130434782609	2.02597826086957	0.0160417385898724	0.214359223161165
GO:0030159	signaling receptor complex adaptor activity	12/2200	52/18639	0.230769230769231	1.95513986013986	0.0161397411035932	0.214359223161165
GO:0009055	electron transfer activity	22/2200	116/18639	0.189655172413793	1.60681034482759	0.0162714921871511	0.214359223161165
GO:0042277	peptide binding	41/2200	249/18639	0.164658634538153	1.39503285870756	0.0171003094219926	0.220893394141687
GO:0019955	cytokine binding	26/2200	144/18639	0.180555555555556	1.52971590909091	0.017699871107105	0.220893394141687
GO:0051020	GTPase binding	50/2200	315/18639	0.158730158730159	1.34480519480519	0.0178334506022252	0.220893394141687
GO:0008201	heparin binding	30/2200	172/18639	0.174418604651163	1.47772198731501	0.0182069362601441	0.220893394141687
GO:0008191	metalloendopeptidase inhibitor activity	5/2200	14/18639	0.357142857142857	3.02581168831169	0.0182538848846136	0.220893394141687
GO:0031593	polyubiquitin modification-dependent protein binding	13/2200	59/18639	0.220338983050847	1.8667719568567	0.0183581425255333	0.220893394141687
GO:0008137	NADH dehydrogenase (ubiquinone) activity	10/2200	41/18639	0.24390243902439	2.06640798226164	0.0185121073260668	0.220893394141687
GO:0140318	protein transporter activity	10/2200	41/18639	0.24390243902439	2.06640798226164	0.0185121073260668	0.220893394141687
GO:0004864	protein phosphatase inhibitor activity	12/2200	53/18639	0.226415094339623	1.91825042881647	0.0186867724594248	0.220893394141687
GO:0016860	intramolecular oxidoreductase activity	12/2200	53/18639	0.226415094339623	1.91825042881647	0.0186867724594248	0.220893394141687
GO:0140938	histone H3 methyltransferase activity	11/2200	47/18639	0.234042553191489	1.98287234042553	0.0187722933965295	0.220893394141687
GO:0051721	protein phosphatase 2A binding	8/2200	30/18639	0.266666666666667	2.25927272727273	0.0200408564454371	0.23215042008207
GO:0046332	SMAD binding	16/2200	79/18639	0.20253164556962	1.71590333716916	0.0208781597837133	0.23215042008207
GO:0001098	basal transcription machinery binding	13/2200	60/18639	0.216666666666667	1.83565909090909	0.0209797891517355	0.23215042008207
GO:0001099	basal RNA polymerase II transcription machinery binding	13/2200	60/18639	0.216666666666667	1.83565909090909	0.0209797891517355	0.23215042008207
GO:0061775	cohesin loader activity	27/2200	153/18639	0.176470588235294	1.49510695187166	0.02098313957882	0.23215042008207
GO:0003689	DNA clamp loader activity	28/2200	160/18639	0.175	1.48264772727273	0.0210717002812711	0.23215042008207
GO:0008094	ATP-dependent activity, acting on DNA	35/2200	210/18639	0.166666666666667	1.41204545454545	0.022014393872914	0.23215042008207
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/2200	10/18639	0.4	3.38890909090909	0.0226021036053501	0.23215042008207
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	4/2200	10/18639	0.4	3.38890909090909	0.0226021036053501	0.23215042008207
GO:0033204	ribonuclease P RNA binding	4/2200	10/18639	0.4	3.38890909090909	0.0226021036053501	0.23215042008207
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	4/2200	10/18639	0.4	3.38890909090909	0.0226021036053501	0.23215042008207
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	4/2200	10/18639	0.4	3.38890909090909	0.0226021036053501	0.23215042008207
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	4/2200	10/18639	0.4	3.38890909090909	0.0226021036053501	0.23215042008207
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	4/2200	10/18639	0.4	3.38890909090909	0.0226021036053501	0.23215042008207
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	4/2200	10/18639	0.4	3.38890909090909	0.0226021036053501	0.23215042008207
GO:0140098	catalytic activity, acting on RNA	59/2200	387/18639	0.152454780361757	1.29163847780127	0.0234386636045771	0.238719834359222
GO:0043024	ribosomal small subunit binding	6/2200	20/18639	0.3	2.54168181818182	0.024096410496738	0.243347409499099
GO:0070325	lipoprotein particle receptor binding	8/2200	31/18639	0.258064516129032	2.18639296187683	0.0242945846117088	0.243347409499099
GO:0004129	cytochrome-c oxidase activity	5/2200	15/18639	0.333333333333333	2.82409090909091	0.0247738459401646	0.244113018532354
GO:0051371	muscle alpha-actinin binding	5/2200	15/18639	0.333333333333333	2.82409090909091	0.0247738459401646	0.244113018532354
GO:0001222	transcription corepressor binding	11/2200	49/18639	0.224489795918367	1.9019387755102	0.0252427799612241	0.246727817040352
GO:0003697	single-stranded DNA binding	22/2200	121/18639	0.181818181818182	1.5404132231405	0.0255471206614629	0.247704881933544
GO:0005539	glycosaminoglycan binding	39/2200	242/18639	0.161157024793388	1.36536626596544	0.0268152486425542	0.257937153609331
GO:0050750	low-density lipoprotein particle receptor binding	7/2200	26/18639	0.269230769230769	2.2809965034965	0.0274518801983305	0.261981722837611
GO:0019212	phosphatase inhibitor activity	12/2200	56/18639	0.214285714285714	1.81548701298701	0.0281294005040613	0.265975096285405
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	37/2200	229/18639	0.161572052401747	1.3688824930528	0.02932855087164	0.265975096285405
GO:0001046	core promoter sequence-specific DNA binding	10/2200	44/18639	0.227272727272727	1.92551652892562	0.029614446639775	0.265975096285405
GO:0001223	transcription coactivator binding	10/2200	44/18639	0.227272727272727	1.92551652892562	0.029614446639775	0.265975096285405
GO:0003954	NADH dehydrogenase activity	10/2200	44/18639	0.227272727272727	1.92551652892562	0.029614446639775	0.265975096285405
GO:0030020	extracellular matrix structural constituent conferring tensile strength	10/2200	44/18639	0.227272727272727	1.92551652892562	0.029614446639775	0.265975096285405
GO:0016922	nuclear receptor binding	24/2200	137/18639	0.175182481751825	1.48419376244194	0.0305774152653571	0.265975096285405
GO:0000510	H3-H4 histone complex chaperone activity	26/2200	151/18639	0.172185430463576	1.45880192655027	0.0306042117990613	0.265975096285405
GO:0140584	chromatin extrusion motor activity	26/2200	151/18639	0.172185430463576	1.45880192655027	0.0306042117990613	0.265975096285405
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	26/2200	151/18639	0.172185430463576	1.45880192655027	0.0306042117990613	0.265975096285405
GO:0140849	ATP-dependent H2AZ histone chaperone activity	26/2200	151/18639	0.172185430463576	1.45880192655027	0.0306042117990613	0.265975096285405
GO:0004601	peroxidase activity	12/2200	57/18639	0.210526315789474	1.78363636363636	0.0319336832593514	0.265975096285405
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	4/2200	11/18639	0.363636363636364	3.08082644628099	0.0322602297400877	0.265975096285405
GO:0019206	nucleoside kinase activity	4/2200	11/18639	0.363636363636364	3.08082644628099	0.0322602297400877	0.265975096285405
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	4/2200	11/18639	0.363636363636364	3.08082644628099	0.0322602297400877	0.265975096285405
GO:0034511	U3 snoRNA binding	4/2200	11/18639	0.363636363636364	3.08082644628099	0.0322602297400877	0.265975096285405
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	4/2200	11/18639	0.363636363636364	3.08082644628099	0.0322602297400877	0.265975096285405
GO:0003688	DNA replication origin binding	5/2200	16/18639	0.3125	2.64758522727273	0.0326168374014498	0.265975096285405
GO:0005024	transforming growth factor beta receptor activity	5/2200	16/18639	0.3125	2.64758522727273	0.0326168374014498	0.265975096285405
GO:0016675	oxidoreductase activity, acting on a heme group of donors	5/2200	16/18639	0.3125	2.64758522727273	0.0326168374014498	0.265975096285405
GO:0097027	ubiquitin-protein transferase activator activity	5/2200	16/18639	0.3125	2.64758522727273	0.0326168374014498	0.265975096285405
GO:0015616	DNA translocase activity	26/2200	152/18639	0.171052631578947	1.44920454545455	0.0329177099363125	0.265975096285405
GO:0140674	ATP-dependent histone chaperone activity	26/2200	152/18639	0.171052631578947	1.44920454545455	0.0329177099363125	0.265975096285405
GO:0023026	MHC class II protein complex binding	7/2200	27/18639	0.259259259259259	2.19651515151515	0.0333979405696619	0.26806823821477
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	28/2200	167/18639	0.167664670658683	1.42050081654872	0.034880040439279	0.278122427713199
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	7/2200	28/18639	0.25	2.11806818181818	0.0401420940123871	0.317988352568713
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/2200	59/18639	0.203389830508475	1.72317411402157	0.0406205713714373	0.319689172092091
GO:0019207	kinase regulator activity	44/2200	287/18639	0.153310104529617	1.2988850174216	0.0416212009197888	0.320962200834061
GO:0004029	aldehyde dehydrogenase (NAD+) activity	5/2200	17/18639	0.294117647058824	2.4918449197861	0.0418416070394238	0.320962200834061
GO:0004659	prenyltransferase activity	5/2200	17/18639	0.294117647058824	2.4918449197861	0.0418416070394238	0.320962200834061
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	5/2200	17/18639	0.294117647058824	2.4918449197861	0.0418416070394238	0.320962200834061
GO:0051219	phosphoprotein binding	17/2200	93/18639	0.182795698924731	1.54869501466276	0.0436041479919881	0.32106772319742
GO:0003995	acyl-CoA dehydrogenase activity	4/2200	12/18639	0.333333333333333	2.82409090909091	0.0439746221541021	0.32106772319742
GO:0004526	ribonuclease P activity	4/2200	12/18639	0.333333333333333	2.82409090909091	0.0439746221541021	0.32106772319742
GO:0016273	arginine N-methyltransferase activity	4/2200	12/18639	0.333333333333333	2.82409090909091	0.0439746221541021	0.32106772319742
GO:0016274	protein-arginine N-methyltransferase activity	4/2200	12/18639	0.333333333333333	2.82409090909091	0.0439746221541021	0.32106772319742
GO:0036009	protein-glutamine N-methyltransferase activity	4/2200	12/18639	0.333333333333333	2.82409090909091	0.0439746221541021	0.32106772319742
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	4/2200	12/18639	0.333333333333333	2.82409090909091	0.0439746221541021	0.32106772319742
GO:0141221	histone deacetylase activity, hydrolytic mechanism	4/2200	12/18639	0.333333333333333	2.82409090909091	0.0439746221541021	0.32106772319742
GO:0008171	O-methyltransferase activity	6/2200	23/18639	0.260869565217391	2.2101581027668	0.0462234967071137	0.331496319580011
GO:0042171	lysophosphatidic acid acyltransferase activity	6/2200	23/18639	0.260869565217391	2.2101581027668	0.0462234967071137	0.331496319580011
GO:0071617	lysophospholipid acyltransferase activity	6/2200	23/18639	0.260869565217391	2.2101581027668	0.0462234967071137	0.331496319580011
GO:0042054	histone methyltransferase activity	13/2200	67/18639	0.194029850746269	1.64387381275441	0.0476647343965404	0.339821518168276
GO:0048029	monosaccharide binding	14/2200	74/18639	0.189189189189189	1.60286240786241	0.0492805189459857	0.349286485161022
GO:0140097	catalytic activity, acting on DNA	50/2200	336/18639	0.148809523809524	1.26075487012987	0.0499077458848276	0.351675511700064
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	10/2200	48/18639	0.208333333333333	1.76505681818182	0.0507828519599523	0.354093300464175
GO:0019905	syntaxin binding	12/2200	61/18639	0.19672131147541	1.66667660208644	0.0508351767993123	0.354093300464175
GO:0008276	protein methyltransferase activity	17/2200	95/18639	0.178947368421053	1.51609090909091	0.0518610037735055	0.355358850451576
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	5/2200	18/18639	0.277777777777778	2.35340909090909	0.0524828665270892	0.355358850451576
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	5/2200	18/18639	0.277777777777778	2.35340909090909	0.0524828665270892	0.355358850451576
GO:0004706	JUN kinase kinase kinase activity	5/2200	18/18639	0.277777777777778	2.35340909090909	0.0524828665270892	0.355358850451576
GO:0070628	proteasome binding	5/2200	18/18639	0.277777777777778	2.35340909090909	0.0524828665270892	0.355358850451576
GO:0019887	protein kinase regulator activity	39/2200	255/18639	0.152941176470588	1.29575935828877	0.0540728741898678	0.364090686211776
GO:0016409	palmitoyltransferase activity	8/2200	36/18639	0.222222222222222	1.88272727272727	0.0550597756797716	0.366661802878479
GO:0044390	ubiquitin-like protein conjugating enzyme binding	8/2200	36/18639	0.222222222222222	1.88272727272727	0.0550597756797716	0.366661802878479
GO:0001091	RNA polymerase II general transcription initiation factor binding	6/2200	24/18639	0.25	2.11806818181818	0.0556978442863076	0.366879278668505
GO:0050431	transforming growth factor beta binding	6/2200	24/18639	0.25	2.11806818181818	0.0556978442863076	0.366879278668505
GO:0061134	peptidase regulator activity	35/2200	226/18639	0.154867256637168	1.31207763475463	0.0562486791266599	0.368504860008172
GO:0004535	poly(A)-specific ribonuclease activity	4/2200	13/18639	0.307692307692308	2.60685314685315	0.057752412942003	0.374309756608062
GO:0070123	transforming growth factor beta receptor activity, type III	4/2200	13/18639	0.307692307692308	2.60685314685315	0.057752412942003	0.374309756608062
GO:0048156	tau protein binding	9/2200	43/18639	0.209302325581395	1.77326638477801	0.0604662565413888	0.388406277945132
GO:0022853	active monoatomic ion transmembrane transporter activity	20/2200	118/18639	0.169491525423729	1.43597842835131	0.0605683057191666	0.388406277945132
GO:0004674	protein serine/threonine kinase activity	62/2200	433/18639	0.143187066974596	1.21311988242704	0.0614824860734503	0.39219354274222
GO:0061135	endopeptidase regulator activity	29/2200	184/18639	0.157608695652174	1.33530385375494	0.0638830678907935	0.405373184731108
GO:0042800	histone H3K4 methyltransferase activity	5/2200	19/18639	0.263157894736842	2.22954545454545	0.0645517285269782	0.40748278632655
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	6/2200	25/18639	0.24	2.03334545454545	0.0662549170441308	0.416067147448116
GO:0016504	peptidase activator activity	11/2200	57/18639	0.192982456140351	1.635	0.0672380951899819	0.419942828784618
GO:0015078	proton transmembrane transporter activity	29/2200	185/18639	0.156756756756757	1.328085995086	0.0675650590866341	0.419942828784618
GO:0008017	microtubule binding	41/2200	276/18639	0.148550724637681	1.25856225296443	0.0715016840194286	0.442143066487487
GO:0042162	telomeric DNA binding	8/2200	38/18639	0.210526315789474	1.78363636363636	0.0722266132532196	0.444358656156864
GO:0008195	phosphatidate phosphatase activity	4/2200	14/18639	0.285714285714286	2.42064935064935	0.0735518241649587	0.447963873808693
GO:0032036	myosin heavy chain binding	4/2200	14/18639	0.285714285714286	2.42064935064935	0.0735518241649587	0.447963873808693
GO:0008408	3'-5' exonuclease activity	11/2200	58/18639	0.189655172413793	1.60681034482759	0.0745274617842463	0.449389471057246
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	11/2200	58/18639	0.189655172413793	1.60681034482759	0.0745274617842463	0.449389471057246
GO:0031406	carboxylic acid binding	29/2200	187/18639	0.155080213903743	1.31388186679631	0.0753697437373413	0.451261564761481
GO:0051059	NF-kappaB binding	7/2200	32/18639	0.21875	1.85330965909091	0.0755825888173108	0.451261564761481
GO:0005112	Notch binding	6/2200	26/18639	0.230769230769231	1.95513986013986	0.0778958280978708	0.456911321057559
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	5/2200	20/18639	0.25	2.11806818181818	0.0780368345370583	0.456911321057559
GO:0016004	phospholipase activator activity	5/2200	20/18639	0.25	2.11806818181818	0.0780368345370583	0.456911321057559
GO:0061608	nuclear import signal receptor activity	5/2200	20/18639	0.25	2.11806818181818	0.0780368345370583	0.456911321057559
GO:0140030	modification-dependent protein binding	27/2200	173/18639	0.15606936416185	1.32226221755124	0.0788215018763474	0.459286828241024
GO:0070063	RNA polymerase binding	11/2200	59/18639	0.186440677966102	1.57957627118644	0.0822977908371818	0.477248432988825
GO:0043177	organic acid binding	29/2200	189/18639	0.153439153439153	1.29997835497835	0.0837742911926008	0.483497337740153
GO:0016874	ligase activity	26/2200	167/18639	0.155688622754491	1.31903647250953	0.0851871292475496	0.489321330085451
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	11/2200	60/18639	0.183333333333333	1.55325	0.090551612531447	0.498390072973395
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	11/2200	60/18639	0.183333333333333	1.55325	0.090551612531447	0.498390072973395
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	11/2200	60/18639	0.183333333333333	1.55325	0.090551612531447	0.498390072973395
GO:0008320	protein transmembrane transporter activity	6/2200	27/18639	0.222222222222222	1.88272727272727	0.0906095102487877	0.498390072973395
GO:0015252	proton channel activity	6/2200	27/18639	0.222222222222222	1.88272727272727	0.0906095102487877	0.498390072973395
GO:0004559	alpha-mannosidase activity	4/2200	15/18639	0.266666666666667	2.25927272727273	0.0912892707921565	0.498390072973395
GO:0031386	protein tag activity	4/2200	15/18639	0.266666666666667	2.25927272727273	0.0912892707921565	0.498390072973395
GO:0042809	nuclear vitamin D receptor binding	4/2200	15/18639	0.266666666666667	2.25927272727273	0.0912892707921565	0.498390072973395
GO:0141047	molecular tag activity	4/2200	15/18639	0.266666666666667	2.25927272727273	0.0912892707921565	0.498390072973395
GO:0141050	histone H3K deacetylase activity	4/2200	15/18639	0.266666666666667	2.25927272727273	0.0912892707921565	0.498390072973395
GO:0141051	histone H4K deacetylase activity	4/2200	15/18639	0.266666666666667	2.25927272727273	0.0912892707921565	0.498390072973395
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	5/2200	21/18639	0.238095238095238	2.01720779220779	0.0929060126017741	0.502687889613171
GO:0140312	cargo adaptor activity	5/2200	21/18639	0.238095238095238	2.01720779220779	0.0929060126017741	0.502687889613171
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	11/2200	61/18639	0.180327868852459	1.5277868852459	0.0992892283925168	0.532140085415554
GO:0140223	general transcription initiation factor activity	12/2200	68/18639	0.176470588235294	1.49510695187166	0.099698333443084	0.532140085415554
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	8/2200	41/18639	0.195121951219512	1.65312638580931	0.103418917750786	0.532140085415554
GO:0061650	ubiquitin-like protein conjugating enzyme activity	8/2200	41/18639	0.195121951219512	1.65312638580931	0.103418917750786	0.532140085415554
GO:0046875	ephrin receptor binding	6/2200	28/18639	0.214285714285714	1.81548701298701	0.104373351040533	0.532140085415554
GO:0051393	alpha-actinin binding	6/2200	28/18639	0.214285714285714	1.81548701298701	0.104373351040533	0.532140085415554
GO:0097718	disordered domain specific binding	6/2200	28/18639	0.214285714285714	1.81548701298701	0.104373351040533	0.532140085415554
GO:0001094	TFIID-class transcription factor complex binding	3/2200	10/18639	0.3	2.54168181818182	0.104496155386883	0.532140085415554
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/2200	10/18639	0.3	2.54168181818182	0.104496155386883	0.532140085415554
GO:0016783	sulfurtransferase activity	3/2200	10/18639	0.3	2.54168181818182	0.104496155386883	0.532140085415554
GO:0031434	mitogen-activated protein kinase kinase binding	3/2200	10/18639	0.3	2.54168181818182	0.104496155386883	0.532140085415554
GO:0043295	glutathione binding	3/2200	10/18639	0.3	2.54168181818182	0.104496155386883	0.532140085415554
GO:0140940	histone H2A methyltransferase activity	3/2200	10/18639	0.3	2.54168181818182	0.104496155386883	0.532140085415554
GO:1990259	histone H2AQ104 methyltransferase activity	3/2200	10/18639	0.3	2.54168181818182	0.104496155386883	0.532140085415554
GO:0017022	myosin binding	13/2200	76/18639	0.171052631578947	1.44920454545455	0.107788147586747	0.535818085958167
GO:0002039	p53 binding	12/2200	69/18639	0.173913043478261	1.47343873517787	0.108404640096104	0.535818085958167
GO:0034062	5'-3' RNA polymerase activity	5/2200	22/18639	0.227272727272727	1.92551652892562	0.109108317577014	0.535818085958167
GO:0050321	tau-protein kinase activity	5/2200	22/18639	0.227272727272727	1.92551652892562	0.109108317577014	0.535818085958167
GO:0061133	endopeptidase activator activity	5/2200	22/18639	0.227272727272727	1.92551652892562	0.109108317577014	0.535818085958167
GO:0097747	RNA polymerase activity	5/2200	22/18639	0.227272727272727	1.92551652892562	0.109108317577014	0.535818085958167
GO:0140035	ubiquitin-like protein reader activity	5/2200	22/18639	0.227272727272727	1.92551652892562	0.109108317577014	0.535818085958167
GO:0005521	lamin binding	4/2200	16/18639	0.25	2.11806818181818	0.110846748589059	0.535818085958167
GO:0008296	3'-5'-DNA exonuclease activity	4/2200	16/18639	0.25	2.11806818181818	0.110846748589059	0.535818085958167
GO:0015562	efflux transmembrane transporter activity	4/2200	16/18639	0.25	2.11806818181818	0.110846748589059	0.535818085958167
GO:0015923	mannosidase activity	4/2200	16/18639	0.25	2.11806818181818	0.110846748589059	0.535818085958167
GO:0000175	3'-5'-RNA exonuclease activity	7/2200	35/18639	0.2	1.69445454545455	0.111242059174463	0.535818085958167
GO:0016229	steroid dehydrogenase activity	7/2200	35/18639	0.2	1.69445454545455	0.111242059174463	0.535818085958167
GO:0008170	N-methyltransferase activity	16/2200	98/18639	0.163265306122449	1.38322820037106	0.111407720842787	0.535818085958167
GO:0004402	histone acetyltransferase activity	8/2200	42/18639	0.19047619047619	1.61376623376623	0.115247727348274	0.549922226559478
GO:0043175	RNA polymerase core enzyme binding	8/2200	42/18639	0.19047619047619	1.61376623376623	0.115247727348274	0.549922226559478
GO:0051540	metal cluster binding	13/2200	77/18639	0.168831168831169	1.43038370720189	0.11642122207404	0.55334322021073
GO:0016417	S-acyltransferase activity	6/2200	29/18639	0.206896551724138	1.75288401253918	0.119154014369108	0.564119786778746
GO:0043178	alcohol binding	15/2200	92/18639	0.16304347826087	1.38134881422925	0.121367040976191	0.572361298300171
GO:0005484	SNAP receptor activity	7/2200	36/18639	0.194444444444444	1.64738636363636	0.124803300018009	0.575117584403813
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	7/2200	36/18639	0.194444444444444	1.64738636363636	0.124803300018009	0.575117584403813
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	7/2200	36/18639	0.194444444444444	1.64738636363636	0.124803300018009	0.575117584403813
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	7/2200	36/18639	0.194444444444444	1.64738636363636	0.124803300018009	0.575117584403813
GO:0019199	transmembrane receptor protein kinase activity	13/2200	78/18639	0.166666666666667	1.41204545454545	0.125443150906448	0.575117584403813
GO:0017134	fibroblast growth factor binding	5/2200	23/18639	0.217391304347826	1.84179841897233	0.126576323374209	0.575117584403813
GO:0019787	ubiquitin-like protein transferase activity	65/2200	479/18639	0.135699373695198	1.14968210286582	0.127578228893238	0.575117584403813
GO:0031267	small GTPase binding	40/2200	283/18639	0.141342756183746	1.19749437841311	0.129913646500417	0.575117584403813
GO:0005536	D-glucose binding	3/2200	11/18639	0.272727272727273	2.31061983471074	0.131584627504431	0.575117584403813
GO:0008432	JUN kinase binding	3/2200	11/18639	0.272727272727273	2.31061983471074	0.131584627504431	0.575117584403813
GO:0019107	myristoyltransferase activity	3/2200	11/18639	0.272727272727273	2.31061983471074	0.131584627504431	0.575117584403813
GO:0048185	activin binding	3/2200	11/18639	0.272727272727273	2.31061983471074	0.131584627504431	0.575117584403813
GO:0050786	RAGE receptor binding	3/2200	11/18639	0.272727272727273	2.31061983471074	0.131584627504431	0.575117584403813
GO:0050998	nitric-oxide synthase binding	3/2200	11/18639	0.272727272727273	2.31061983471074	0.131584627504431	0.575117584403813
GO:0140537	transcription regulator activator activity	3/2200	11/18639	0.272727272727273	2.31061983471074	0.131584627504431	0.575117584403813
GO:1900750	oligopeptide binding	3/2200	11/18639	0.272727272727273	2.31061983471074	0.131584627504431	0.575117584403813
GO:0004549	tRNA-specific ribonuclease activity	4/2200	17/18639	0.235294117647059	1.99347593582888	0.1320790998351	0.575117584403813
GO:0017110	nucleoside diphosphate phosphatase activity	4/2200	17/18639	0.235294117647059	1.99347593582888	0.1320790998351	0.575117584403813
GO:0038191	neuropilin binding	4/2200	17/18639	0.235294117647059	1.99347593582888	0.1320790998351	0.575117584403813
GO:1990226	histone methyltransferase binding	4/2200	17/18639	0.235294117647059	1.99347593582888	0.1320790998351	0.575117584403813
GO:0016209	antioxidant activity	14/2200	86/18639	0.162790697674419	1.37920718816068	0.132390929083056	0.575117584403813
GO:0050660	flavin adenine dinucleotide binding	14/2200	86/18639	0.162790697674419	1.37920718816068	0.132390929083056	0.575117584403813
GO:0031624	ubiquitin conjugating enzyme binding	6/2200	30/18639	0.2	1.69445454545455	0.134908406512343	0.58396067390343
GO:0004866	endopeptidase inhibitor activity	24/2200	161/18639	0.149068322981366	1.26294748729531	0.135963220127953	0.58643210959103
GO:0023023	MHC protein complex binding	7/2200	37/18639	0.189189189189189	1.60286240786241	0.139158401597921	0.595971670447633
GO:0042805	actinin binding	7/2200	37/18639	0.189189189189189	1.60286240786241	0.139158401597921	0.595971670447633
GO:0030295	protein kinase activator activity	21/2200	139/18639	0.151079136690647	1.27998364944408	0.140766550765884	0.598446779129563
GO:0019205	nucleobase-containing compound kinase activity	8/2200	44/18639	0.181818181818182	1.5404132231405	0.140962456901476	0.598446779129563
GO:0005048	signal sequence binding	9/2200	51/18639	0.176470588235294	1.49510695187166	0.14121763929955	0.598446779129563
GO:0060229	lipase activator activity	5/2200	24/18639	0.208333333333333	1.76505681818182	0.14522855471313	0.61117016775109
GO:0070840	dynein complex binding	5/2200	24/18639	0.208333333333333	1.76505681818182	0.14522855471313	0.61117016775109
GO:0004197	cysteine-type endopeptidase activity	14/2200	88/18639	0.159090909090909	1.34786157024793	0.151207876437294	0.631342656780729
GO:0019209	kinase activator activity	22/2200	148/18639	0.148648648648649	1.25939189189189	0.15130967220749	0.631342656780729
GO:0005164	tumor necrosis factor receptor binding	6/2200	31/18639	0.193548387096774	1.63979472140762	0.151584746801314	0.631342656780729
GO:0005501	retinoid binding	7/2200	38/18639	0.184210526315789	1.56068181818182	0.154272031224144	0.633881408698348
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	7/2200	38/18639	0.184210526315789	1.56068181818182	0.154272031224144	0.633881408698348
GO:0019840	isoprenoid binding	7/2200	38/18639	0.184210526315789	1.56068181818182	0.154272031224144	0.633881408698348
GO:0035615	clathrin adaptor activity	4/2200	18/18639	0.222222222222222	1.88272727272727	0.154820880780246	0.633881408698348
GO:0050811	GABA receptor binding	4/2200	18/18639	0.222222222222222	1.88272727272727	0.154820880780246	0.633881408698348
GO:0000995	RNA polymerase III general transcription initiation factor activity	3/2200	12/18639	0.25	2.11806818181818	0.160787962621207	0.633881408698348
GO:0005025	transforming growth factor beta receptor activity, type I	3/2200	12/18639	0.25	2.11806818181818	0.160787962621207	0.633881408698348
GO:0005026	transforming growth factor beta receptor activity, type II	3/2200	12/18639	0.25	2.11806818181818	0.160787962621207	0.633881408698348
GO:0016361	activin receptor activity, type I	3/2200	12/18639	0.25	2.11806818181818	0.160787962621207	0.633881408698348
GO:0016362	activin receptor activity, type II	3/2200	12/18639	0.25	2.11806818181818	0.160787962621207	0.633881408698348
GO:0017002	activin receptor activity	3/2200	12/18639	0.25	2.11806818181818	0.160787962621207	0.633881408698348
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	3/2200	12/18639	0.25	2.11806818181818	0.160787962621207	0.633881408698348
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	3/2200	12/18639	0.25	2.11806818181818	0.160787962621207	0.633881408698348
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	3/2200	12/18639	0.25	2.11806818181818	0.160787962621207	0.633881408698348
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	3/2200	12/18639	0.25	2.11806818181818	0.160787962621207	0.633881408698348
GO:0016853	isomerase activity	26/2200	180/18639	0.144444444444444	1.22377272727273	0.161220894863614	0.633881408698348
GO:0016755	aminoacyltransferase activity	66/2200	496/18639	0.133064516129032	1.12735887096774	0.162995469891674	0.633881408698348
GO:0003707	nuclear steroid receptor activity	5/2200	25/18639	0.2	1.69445454545455	0.16497196413038	0.633881408698348
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	5/2200	25/18639	0.2	1.69445454545455	0.16497196413038	0.633881408698348
GO:0019706	protein-cysteine S-palmitoyltransferase activity	5/2200	25/18639	0.2	1.69445454545455	0.16497196413038	0.633881408698348
GO:0019707	protein-cysteine S-acyltransferase activity	5/2200	25/18639	0.2	1.69445454545455	0.16497196413038	0.633881408698348
GO:0042974	nuclear retinoic acid receptor binding	5/2200	25/18639	0.2	1.69445454545455	0.16497196413038	0.633881408698348
GO:0015631	tubulin binding	52/2200	385/18639	0.135064935064935	1.14430696576151	0.166361011561799	0.633881408698348
GO:0019842	vitamin binding	22/2200	150/18639	0.146666666666667	1.2426	0.166571060410031	0.633881408698348
GO:0008168	methyltransferase activity	29/2200	204/18639	0.142156862745098	1.20439171122995	0.166633447304487	0.633881408698348
GO:0016251	RNA polymerase II general transcription initiation factor activity	9/2200	53/18639	0.169811320754717	1.43868782161235	0.167311865688786	0.633881408698348
GO:0034212	protein N-acetyltransferase activity	9/2200	53/18639	0.169811320754717	1.43868782161235	0.167311865688786	0.633881408698348
GO:0140296	general transcription initiation factor binding	9/2200	53/18639	0.169811320754717	1.43868782161235	0.167311865688786	0.633881408698348
GO:0004842	ubiquitin-protein transferase activity	60/2200	449/18639	0.133630289532294	1.13215225754201	0.167361428039168	0.633881408698348
GO:0022884	macromolecule transmembrane transporter activity	6/2200	32/18639	0.1875	1.58855113636364	0.169123706336084	0.63460660086481
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/2200	32/18639	0.1875	1.58855113636364	0.169123706336084	0.63460660086481
GO:0140142	nucleocytoplasmic carrier activity	6/2200	32/18639	0.1875	1.58855113636364	0.169123706336084	0.63460660086481
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	7/2200	39/18639	0.179487179487179	1.52066433566434	0.170103519663052	0.636313166146973
GO:0003779	actin binding	59/2200	443/18639	0.133182844243792	1.12836137902729	0.17652173612615	0.657023931860348
GO:0015026	coreceptor activity	10/2200	61/18639	0.163934426229508	1.38889716840537	0.177498987253394	0.657023931860348
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	4/2200	19/18639	0.210526315789474	1.78363636363636	0.178892654714451	0.657023931860348
GO:0042577	lipid phosphatase activity	4/2200	19/18639	0.210526315789474	1.78363636363636	0.178892654714451	0.657023931860348
GO:0046527	glucosyltransferase activity	4/2200	19/18639	0.210526315789474	1.78363636363636	0.178892654714451	0.657023931860348
GO:0070003	threonine-type peptidase activity	4/2200	19/18639	0.210526315789474	1.78363636363636	0.178892654714451	0.657023931860348
GO:0051536	iron-sulfur cluster binding	12/2200	76/18639	0.157894736842105	1.33772727272727	0.18103118310211	0.659317392510492
GO:0015485	cholesterol binding	9/2200	54/18639	0.166666666666667	1.41204545454545	0.181149085566001	0.659317392510492
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	9/2200	54/18639	0.166666666666667	1.41204545454545	0.181149085566001	0.659317392510492
GO:0043495	protein-membrane adaptor activity	8/2200	47/18639	0.170212765957447	1.44208897485493	0.184301108282782	0.660053228864378
GO:0061733	protein-lysine-acetyltransferase activity	8/2200	47/18639	0.170212765957447	1.44208897485493	0.184301108282782	0.660053228864378
GO:0004529	DNA exonuclease activity	5/2200	26/18639	0.192307692307692	1.62928321678322	0.185704377471454	0.660053228864378
GO:0050681	nuclear androgen receptor binding	5/2200	26/18639	0.192307692307692	1.62928321678322	0.185704377471454	0.660053228864378
GO:0097602	cullin family protein binding	5/2200	26/18639	0.192307692307692	1.62928321678322	0.185704377471454	0.660053228864378
GO:0016279	protein-lysine N-methyltransferase activity	11/2200	69/18639	0.159420289855072	1.35065217391304	0.185917938371923	0.660053228864378
GO:0004532	RNA exonuclease activity	7/2200	40/18639	0.175	1.48264772727273	0.186607498160722	0.660053228864378
GO:0004527	exonuclease activity	13/2200	84/18639	0.154761904761905	1.31118506493507	0.187373400203219	0.660053228864378
GO:0071889	14-3-3 protein binding	6/2200	33/18639	0.181818181818182	1.5404132231405	0.187459581864835	0.660053228864378
GO:0140311	protein sequestering activity	6/2200	33/18639	0.181818181818182	1.5404132231405	0.187459581864835	0.660053228864378
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/2200	13/18639	0.230769230769231	1.95513986013986	0.191698627524968	0.660053228864378
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/2200	13/18639	0.230769230769231	1.95513986013986	0.191698627524968	0.660053228864378
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/2200	13/18639	0.230769230769231	1.95513986013986	0.191698627524968	0.660053228864378
GO:0005542	folic acid binding	3/2200	13/18639	0.230769230769231	1.95513986013986	0.191698627524968	0.660053228864378
GO:0017154	semaphorin receptor activity	3/2200	13/18639	0.230769230769231	1.95513986013986	0.191698627524968	0.660053228864378
GO:0043560	insulin receptor substrate binding	3/2200	13/18639	0.230769230769231	1.95513986013986	0.191698627524968	0.660053228864378
GO:0089720	caspase binding	3/2200	13/18639	0.230769230769231	1.95513986013986	0.191698627524968	0.660053228864378
GO:0097157	pre-mRNA intronic binding	3/2200	13/18639	0.230769230769231	1.95513986013986	0.191698627524968	0.660053228864378
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	3/2200	13/18639	0.230769230769231	1.95513986013986	0.191698627524968	0.660053228864378
GO:0035403	histone H3T6 kinase activity	34/2200	247/18639	0.137651821862348	1.16622377622378	0.192279638391657	0.66009500491364
GO:0052689	carboxylic ester hydrolase activity	14/2200	92/18639	0.152173913043478	1.28925889328063	0.192800026187647	0.66009500491364
GO:0030414	peptidase inhibitor activity	24/2200	169/18639	0.142011834319527	1.2031629908553	0.194977935473278	0.665503061585053
GO:0008374	O-acyltransferase activity	9/2200	55/18639	0.163636363636364	1.38637190082645	0.195477796967227	0.665503061585053
GO:0016278	lysine N-methyltransferase activity	11/2200	70/18639	0.157142857142857	1.33135714285714	0.198666036479512	0.674462846535487
GO:0016879	ligase activity, forming carbon-nitrogen bonds	8/2200	48/18639	0.166666666666667	1.41204545454545	0.199891335668113	0.676727091703221
GO:0000339	RNA cap binding	4/2200	20/18639	0.2	1.69445454545455	0.2041066097588	0.68336246140239
GO:0015095	magnesium ion transmembrane transporter activity	4/2200	20/18639	0.2	1.69445454545455	0.2041066097588	0.68336246140239
GO:0016408	C-acyltransferase activity	4/2200	20/18639	0.2	1.69445454545455	0.2041066097588	0.68336246140239
GO:0140939	histone H4 methyltransferase activity	4/2200	20/18639	0.2	1.69445454545455	0.2041066097588	0.68336246140239
GO:0008376	acetylgalactosaminyltransferase activity	6/2200	34/18639	0.176470588235294	1.49510695187166	0.206521475959807	0.687648430943094
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	6/2200	34/18639	0.176470588235294	1.49510695187166	0.206521475959807	0.687648430943094
GO:0004364	glutathione transferase activity	5/2200	27/18639	0.185185185185185	1.56893939393939	0.207316847294787	0.688405531291184
GO:0106310	protein serine kinase activity	48/2200	361/18639	0.132963988919668	1.12650717703349	0.208155689117442	0.68930244592989
GO:0042562	hormone binding	14/2200	94/18639	0.148936170212766	1.26182785299807	0.215418498779938	0.6929914854965
GO:0016763	pentosyltransferase activity	8/2200	49/18639	0.163265306122449	1.38322820037106	0.215991282622276	0.6929914854965
GO:0004536	DNA nuclease activity	10/2200	64/18639	0.15625	1.32379261363636	0.218546385276413	0.6929914854965
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	33/2200	243/18639	0.135802469135802	1.15055555555556	0.219271688375822	0.6929914854965
GO:0016859	cis-trans isomerase activity	7/2200	42/18639	0.166666666666667	1.41204545454545	0.221431925130373	0.6929914854965
GO:0005545	1-phosphatidylinositol binding	3/2200	14/18639	0.214285714285714	1.81548701298701	0.223920482986789	0.6929914854965
GO:0008174	mRNA methyltransferase activity	3/2200	14/18639	0.214285714285714	1.81548701298701	0.223920482986789	0.6929914854965
GO:0016530	metallochaperone activity	3/2200	14/18639	0.214285714285714	1.81548701298701	0.223920482986789	0.6929914854965
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	3/2200	14/18639	0.214285714285714	1.81548701298701	0.223920482986789	0.6929914854965
GO:0031404	chloride ion binding	3/2200	14/18639	0.214285714285714	1.81548701298701	0.223920482986789	0.6929914854965
GO:0061665	SUMO ligase activity	3/2200	14/18639	0.214285714285714	1.81548701298701	0.223920482986789	0.6929914854965
GO:0070742	C2H2 zinc finger domain binding	3/2200	14/18639	0.214285714285714	1.81548701298701	0.223920482986789	0.6929914854965
GO:0098821	BMP receptor activity	3/2200	14/18639	0.214285714285714	1.81548701298701	0.223920482986789	0.6929914854965
GO:0010485	histone H4 acetyltransferase activity	6/2200	35/18639	0.171428571428571	1.45238961038961	0.226234458742982	0.6929914854965
GO:0004867	serine-type endopeptidase inhibitor activity	14/2200	95/18639	0.147368421052632	1.24854545454545	0.227141388292525	0.6929914854965
GO:0019789	SUMO transferase activity	5/2200	28/18639	0.178571428571429	1.51290584415584	0.229695868219625	0.6929914854965
GO:0036408	histone H3K14 acetyltransferase activity	5/2200	28/18639	0.178571428571429	1.51290584415584	0.229695868219625	0.6929914854965
GO:0046966	nuclear thyroid hormone receptor binding	5/2200	28/18639	0.178571428571429	1.51290584415584	0.229695868219625	0.6929914854965
GO:0051537	2 iron, 2 sulfur cluster binding	5/2200	28/18639	0.178571428571429	1.51290584415584	0.229695868219625	0.6929914854965
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4/2200	21/18639	0.19047619047619	1.61376623376623	0.230271456148688	0.6929914854965
GO:0036122	BMP binding	4/2200	21/18639	0.19047619047619	1.61376623376623	0.230271456148688	0.6929914854965
GO:0051010	microtubule plus-end binding	4/2200	21/18639	0.19047619047619	1.61376623376623	0.230271456148688	0.6929914854965
GO:0070182	DNA polymerase binding	4/2200	21/18639	0.19047619047619	1.61376623376623	0.230271456148688	0.6929914854965
GO:0051087	protein-folding chaperone binding	19/2200	134/18639	0.141791044776119	1.20129240162822	0.230394260060378	0.6929914854965
GO:0140996	histone H3 kinase activity	47/2200	357/18639	0.131652661064426	1.11539724980901	0.231988472547957	0.6929914854965
GO:0032813	tumor necrosis factor receptor superfamily binding	8/2200	50/18639	0.16	1.35556363636364	0.232559764880484	0.6929914854965
GO:0004676	3-phosphoinositide-dependent protein kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0004711	ribosomal protein S6 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0035175	histone H3S10 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0035979	histone H2AXS139 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0044022	histone H3S28 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0044023	histone H4S1 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0044024	histone H2AS1 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0044025	histone H2BS14 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0072354	histone H3T3 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0072371	histone H2AS121 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0072518	Rho-dependent protein serine/threonine kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0140823	histone H2BS36 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0140855	histone H3S57 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0140995	histone H2A kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0140997	histone H4 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0140998	histone H2B kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:1990244	histone H2AT120 kinase activity	33/2200	245/18639	0.13469387755102	1.14116326530612	0.233856037597416	0.6929914854965
GO:0016651	oxidoreductase activity, acting on NAD(P)H	13/2200	88/18639	0.147727272727273	1.25158574380165	0.235319356512435	0.695626975836759
GO:0015399	primary active transmembrane transporter activity	23/2200	166/18639	0.13855421686747	1.1738691128149	0.236444913331907	0.697253613037156
GO:0016407	acetyltransferase activity	14/2200	96/18639	0.145833333333333	1.23553977272727	0.239121785299154	0.703053173776806
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/2200	43/18639	0.162790697674419	1.37920718816068	0.239644120441031	0.703053173776806
GO:0000287	magnesium ion binding	31/2200	230/18639	0.134782608695652	1.14191501976285	0.241067112256267	0.703053173776806
GO:0004677	DNA-dependent protein kinase activity	33/2200	246/18639	0.134146341463415	1.1365243902439	0.241311980438244	0.703053173776806
GO:0140857	histone H3T45 kinase activity	33/2200	246/18639	0.134146341463415	1.1365243902439	0.241311980438244	0.703053173776806
GO:0000993	RNA polymerase II complex binding	6/2200	36/18639	0.166666666666667	1.41204545454545	0.246520690487976	0.716506179547788
GO:0016741	transferase activity, transferring one-carbon groups	29/2200	215/18639	0.134883720930233	1.14277167019028	0.248637782865915	0.719890519202391
GO:0035402	histone H3T11 kinase activity	33/2200	247/18639	0.133603238866397	1.13192307692308	0.24887304252954	0.719890519202391
GO:0035173	histone kinase activity	47/2200	360/18639	0.130555555555556	1.10610227272727	0.250616247877978	0.721373531605877
GO:0016779	nucleotidyltransferase activity	19/2200	136/18639	0.139705882352941	1.1836263368984	0.250753029000095	0.721373531605877
GO:0010484	histone H3 acetyltransferase activity	5/2200	29/18639	0.172413793103448	1.46073667711599	0.252725421105149	0.721373531605877
GO:0004679	AMP-activated protein kinase activity	33/2200	248/18639	0.133064516129032	1.12735887096774	0.256536011113081	0.721373531605877
GO:0005523	tropomyosin binding	3/2200	15/18639	0.2	1.69445454545455	0.257078286035446	0.721373531605877
GO:0016846	carbon-sulfur lyase activity	3/2200	15/18639	0.2	1.69445454545455	0.257078286035446	0.721373531605877
GO:0033130	acetylcholine receptor binding	3/2200	15/18639	0.2	1.69445454545455	0.257078286035446	0.721373531605877
GO:0050780	dopamine receptor binding	3/2200	15/18639	0.2	1.69445454545455	0.257078286035446	0.721373531605877
GO:0004879	nuclear receptor activity	9/2200	59/18639	0.152542372881356	1.29238058551618	0.257090061149632	0.721373531605877
GO:0045309	protein phosphorylated amino acid binding	9/2200	59/18639	0.152542372881356	1.29238058551618	0.257090061149632	0.721373531605877
GO:0008093	cytoskeletal anchor activity	4/2200	22/18639	0.181818181818182	1.5404132231405	0.257196598053504	0.721373531605877
GO:0008649	rRNA methyltransferase activity	4/2200	22/18639	0.181818181818182	1.5404132231405	0.257196598053504	0.721373531605877
GO:0016881	acid-amino acid ligase activity	4/2200	22/18639	0.181818181818182	1.5404132231405	0.257196598053504	0.721373531605877
GO:0016790	thiolester hydrolase activity	7/2200	44/18639	0.159090909090909	1.34786157024793	0.25831362435392	0.721373531605877
GO:0043014	alpha-tubulin binding	7/2200	44/18639	0.159090909090909	1.34786157024793	0.25831362435392	0.721373531605877
GO:0141003	histone H2AX kinase activity	46/2200	354/18639	0.129943502824859	1.10091679506934	0.264125755280857	0.735909000920456
GO:0004518	nuclease activity	28/2200	209/18639	0.133971291866029	1.13504132231405	0.265264557652175	0.737386797877147
GO:0000149	SNARE binding	15/2200	106/18639	0.141509433962264	1.19890651801029	0.266119938622492	0.738071774852313
GO:0043394	proteoglycan binding	6/2200	37/18639	0.162162162162162	1.37388206388206	0.267300488337665	0.739653406085045
GO:0098531	ligand-modulated transcription factor activity	9/2200	60/18639	0.15	1.27084090909091	0.273398122180334	0.754193816929588
GO:0061659	ubiquitin-like protein ligase activity	48/2200	372/18639	0.129032258064516	1.09319648093842	0.275554438746166	0.754193816929588
GO:0035925	mRNA 3'-UTR AU-rich region binding	5/2200	30/18639	0.166666666666667	1.41204545454545	0.27628882402371	0.754193816929588
GO:0043995	histone H4K5 acetyltransferase activity	5/2200	30/18639	0.166666666666667	1.41204545454545	0.27628882402371	0.754193816929588
GO:0043996	histone H4K8 acetyltransferase activity	5/2200	30/18639	0.166666666666667	1.41204545454545	0.27628882402371	0.754193816929588
GO:0043997	histone H4K12 acetyltransferase activity	5/2200	30/18639	0.166666666666667	1.41204545454545	0.27628882402371	0.754193816929588
GO:0046915	transition metal ion transmembrane transporter activity	7/2200	45/18639	0.155555555555556	1.31790909090909	0.277381507542503	0.755475027284299
GO:0032934	sterol binding	10/2200	68/18639	0.147058823529412	1.24592245989305	0.278348609602272	0.756409226094066
GO:0017046	peptide hormone binding	8/2200	53/18639	0.150943396226415	1.27883361921098	0.284637855030906	0.764659288817336
GO:0051018	protein kinase A binding	8/2200	53/18639	0.150943396226415	1.27883361921098	0.284637855030906	0.764659288817336
GO:0005158	insulin receptor binding	4/2200	23/18639	0.173913043478261	1.47343873517787	0.284695603249146	0.764659288817336
GO:0043274	phospholipase binding	4/2200	23/18639	0.173913043478261	1.47343873517787	0.284695603249146	0.764659288817336
GO:0140102	catalytic activity, acting on a rRNA	4/2200	23/18639	0.173913043478261	1.47343873517787	0.284695603249146	0.764659288817336
GO:0051117	ATPase binding	12/2200	84/18639	0.142857142857143	1.21032467532468	0.285169965796564	0.764659288817336
GO:0005109	frizzled binding	6/2200	38/18639	0.157894736842105	1.33772727272727	0.28849332404645	0.766258084436381
GO:0000062	fatty-acyl-CoA binding	3/2200	16/18639	0.1875	1.58855113636364	0.290824025446151	0.766258084436381
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	3/2200	16/18639	0.1875	1.58855113636364	0.290824025446151	0.766258084436381
GO:0005159	insulin-like growth factor receptor binding	3/2200	16/18639	0.1875	1.58855113636364	0.290824025446151	0.766258084436381
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/2200	16/18639	0.1875	1.58855113636364	0.290824025446151	0.766258084436381
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/2200	16/18639	0.1875	1.58855113636364	0.290824025446151	0.766258084436381
GO:0034450	ubiquitin-ubiquitin ligase activity	3/2200	16/18639	0.1875	1.58855113636364	0.290824025446151	0.766258084436381
GO:0043023	ribosomal large subunit binding	3/2200	16/18639	0.1875	1.58855113636364	0.290824025446151	0.766258084436381
GO:0030276	clathrin binding	7/2200	46/18639	0.152173913043478	1.28925889328063	0.296788037699623	0.780275708659312
GO:0016411	acylglycerol O-acyltransferase activity	5/2200	31/18639	0.161290322580645	1.36649560117302	0.30027037733571	0.787722288594979
GO:0051213	dioxygenase activity	13/2200	93/18639	0.139784946236559	1.18429618768328	0.301076885703081	0.788132150047807
GO:0016887	ATP hydrolysis activity	53/2200	417/18639	0.127098321342926	1.07681164159581	0.30242936269405	0.789966352554286
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/2200	39/18639	0.153846153846154	1.30342657342657	0.31001874302525	0.804986460039782
GO:0004622	lysophospholipase activity	4/2200	24/18639	0.166666666666667	1.41204545454545	0.312589012956348	0.804986460039782
GO:0061630	ubiquitin protein ligase activity	45/2200	353/18639	0.127478753541076	1.08003476693278	0.312829399518363	0.804986460039782
GO:0016410	N-acyltransferase activity	13/2200	94/18639	0.138297872340426	1.17169729206963	0.314824528048771	0.804986460039782
GO:0001784	phosphotyrosine residue binding	7/2200	47/18639	0.148936170212766	1.26182785299807	0.31647325034757	0.804986460039782
GO:0140313	molecular sequestering activity	8/2200	55/18639	0.145454545454545	1.2323305785124	0.320875579328774	0.804986460039782
GO:0005507	copper ion binding	9/2200	63/18639	0.142857142857143	1.21032467532468	0.323911270496255	0.804986460039782
GO:0005092	GDP-dissociation inhibitor activity	3/2200	17/18639	0.176470588235294	1.49510695187166	0.324840795219948	0.804986460039782
GO:0015278	intracellularly gated calcium channel activity	3/2200	17/18639	0.176470588235294	1.49510695187166	0.324840795219948	0.804986460039782
GO:0031489	myosin V binding	3/2200	17/18639	0.176470588235294	1.49510695187166	0.324840795219948	0.804986460039782
GO:0046965	nuclear retinoid X receptor binding	3/2200	17/18639	0.176470588235294	1.49510695187166	0.324840795219948	0.804986460039782
GO:0051787	misfolded protein binding	3/2200	17/18639	0.176470588235294	1.49510695187166	0.324840795219948	0.804986460039782
GO:0070403	NAD+ binding	3/2200	17/18639	0.176470588235294	1.49510695187166	0.324840795219948	0.804986460039782
GO:1901567	fatty acid derivative binding	3/2200	17/18639	0.176470588235294	1.49510695187166	0.324840795219948	0.804986460039782
GO:0004519	endonuclease activity	17/2200	127/18639	0.133858267716535	1.13408375089477	0.328125281469644	0.804986460039782
GO:0030331	nuclear estrogen receptor binding	6/2200	40/18639	0.15	1.27084090909091	0.331797198001342	0.804986460039782
GO:0004090	carbonyl reductase (NADPH) activity	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0004382	GDP phosphatase activity	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0005337	nucleoside transmembrane transporter activity	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0005381	iron ion transmembrane transporter activity	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0005528	FK506 binding	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0015643	toxic substance binding	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0016427	tRNA (cytidine) methyltransferase activity	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0030957	Tat protein binding	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0031720	haptoglobin binding	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0032395	MHC class II receptor activity	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0035374	chondroitin sulfate binding	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0043121	neurotrophin binding	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0045322	unmethylated CpG binding	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0047429	nucleoside triphosphate diphosphatase activity	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0070513	death domain binding	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0098505	G-rich strand telomeric DNA binding	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0099122	RNA polymerase II C-terminal domain binding	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0140999	histone H3K4 trimethyltransferase activity	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:1990757	ubiquitin ligase activator activity	2/2200	10/18639	0.2	1.69445454545455	0.334082664521461	0.804986460039782
GO:0140693	molecular condensate scaffold activity	7/2200	48/18639	0.145833333333333	1.23553977272727	0.336377479683087	0.808907748761709
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	17/2200	128/18639	0.1328125	1.12522372159091	0.340220292148723	0.812866798882009
GO:0000030	mannosyltransferase activity	4/2200	25/18639	0.16	1.35556363636364	0.340706546066057	0.812866798882009
GO:0008139	nuclear localization sequence binding	4/2200	25/18639	0.16	1.35556363636364	0.340706546066057	0.812866798882009
GO:0047617	fatty acyl-CoA hydrolase activity	4/2200	25/18639	0.16	1.35556363636364	0.340706546066057	0.812866798882009
GO:0000049	tRNA binding	11/2200	80/18639	0.1375	1.1649375	0.342782283204963	0.814612014204736
GO:0048306	calcium-dependent protein binding	11/2200	80/18639	0.1375	1.1649375	0.342782283204963	0.814612014204736
GO:0016757	glycosyltransferase activity	34/2200	267/18639	0.127340823970037	1.07886618998979	0.344798010627468	0.817798804071412
GO:0019956	chemokine binding	5/2200	33/18639	0.151515151515152	1.28367768595041	0.349038443610189	0.826239440733495
GO:0004540	RNA nuclease activity	16/2200	121/18639	0.132231404958678	1.12030052592036	0.353668126390302	0.832516430027547
GO:0051082	unfolded protein binding	16/2200	121/18639	0.132231404958678	1.12030052592036	0.353668126390302	0.832516430027547
GO:0042169	SH2 domain binding	6/2200	41/18639	0.146341463414634	1.23984478935698	0.353750793287283	0.832516430027547
GO:0015932	nucleobase-containing compound transmembrane transporter activity	8/2200	57/18639	0.140350877192982	1.18909090909091	0.357892954794048	0.83477902316077
GO:0000400	four-way junction DNA binding	3/2200	18/18639	0.166666666666667	1.41204545454545	0.358844778107889	0.83477902316077
GO:0000900	mRNA regulatory element binding translation repressor activity	3/2200	18/18639	0.166666666666667	1.41204545454545	0.358844778107889	0.83477902316077
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	3/2200	18/18639	0.166666666666667	1.41204545454545	0.358844778107889	0.83477902316077
GO:0098641	cadherin binding involved in cell-cell adhesion	3/2200	18/18639	0.166666666666667	1.41204545454545	0.358844778107889	0.83477902316077
GO:1990381	ubiquitin-specific protease binding	3/2200	18/18639	0.166666666666667	1.41204545454545	0.358844778107889	0.83477902316077
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	16/2200	122/18639	0.131147540983607	1.11111773472429	0.366363936695618	0.846767377552683
GO:0008157	protein phosphatase 1 binding	4/2200	26/18639	0.153846153846154	1.30342657342657	0.368888758537802	0.846767377552683
GO:0008198	ferrous iron binding	4/2200	26/18639	0.153846153846154	1.30342657342657	0.368888758537802	0.846767377552683
GO:0016289	acyl-CoA hydrolase activity	4/2200	26/18639	0.153846153846154	1.30342657342657	0.368888758537802	0.846767377552683
GO:0030507	spectrin binding	4/2200	26/18639	0.153846153846154	1.30342657342657	0.368888758537802	0.846767377552683
GO:0070006	metalloaminopeptidase activity	4/2200	26/18639	0.153846153846154	1.30342657342657	0.368888758537802	0.846767377552683
GO:0120014	phospholipid transfer activity	4/2200	26/18639	0.153846153846154	1.30342657342657	0.368888758537802	0.846767377552683
GO:0090482	vitamin transmembrane transporter activity	5/2200	34/18639	0.147058823529412	1.24592245989305	0.373610334584394	0.850829001302341
GO:0004520	DNA endonuclease activity	6/2200	42/18639	0.142857142857143	1.21032467532468	0.375803937980101	0.850829001302341
GO:0008307	structural constituent of muscle	6/2200	42/18639	0.142857142857143	1.21032467532468	0.375803937980101	0.850829001302341
GO:0042056	chemoattractant activity	6/2200	42/18639	0.142857142857143	1.21032467532468	0.375803937980101	0.850829001302341
GO:0005006	epidermal growth factor receptor activity	7/2200	50/18639	0.14	1.18611818181818	0.376608696251885	0.850829001302341
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/2200	11/18639	0.181818181818182	1.5404132231405	0.379082228303023	0.850829001302341
GO:0003953	NAD+ nucleosidase activity	2/2200	11/18639	0.181818181818182	1.5404132231405	0.379082228303023	0.850829001302341
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/2200	11/18639	0.181818181818182	1.5404132231405	0.379082228303023	0.850829001302341
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/2200	11/18639	0.181818181818182	1.5404132231405	0.379082228303023	0.850829001302341
GO:0032050	clathrin heavy chain binding	2/2200	11/18639	0.181818181818182	1.5404132231405	0.379082228303023	0.850829001302341
GO:0035252	UDP-xylosyltransferase activity	2/2200	11/18639	0.181818181818182	1.5404132231405	0.379082228303023	0.850829001302341
GO:0042285	xylosyltransferase activity	2/2200	11/18639	0.181818181818182	1.5404132231405	0.379082228303023	0.850829001302341
GO:0044183	protein folding chaperone	10/2200	75/18639	0.133333333333333	1.12963636363636	0.391643119151135	0.867959806540018
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/2200	19/18639	0.157894736842105	1.33772727272727	0.392585801244158	0.867959806540018
GO:0015245	fatty acid transmembrane transporter activity	3/2200	19/18639	0.157894736842105	1.33772727272727	0.392585801244158	0.867959806540018
GO:0016918	retinal binding	3/2200	19/18639	0.157894736842105	1.33772727272727	0.392585801244158	0.867959806540018
GO:0097001	ceramide binding	3/2200	19/18639	0.157894736842105	1.33772727272727	0.392585801244158	0.867959806540018
GO:0120227	acyl-CoA binding	3/2200	19/18639	0.157894736842105	1.33772727272727	0.392585801244158	0.867959806540018
GO:0140036	ubiquitin-modified protein reader activity	3/2200	19/18639	0.157894736842105	1.33772727272727	0.392585801244158	0.867959806540018
GO:0008173	RNA methyltransferase activity	9/2200	67/18639	0.134328358208955	1.13806648575305	0.393561243869382	0.867959806540018
GO:0030695	GTPase regulator activity	60/2200	489/18639	0.122699386503067	1.03954266592303	0.393919227993136	0.867959806540018
GO:0005010	insulin-like growth factor receptor activity	7/2200	51/18639	0.137254901960784	1.16286096256684	0.396821999269993	0.867959806540018
GO:0005044	scavenger receptor activity	4/2200	27/18639	0.148148148148148	1.25515151515151	0.396988221362675	0.867959806540018
GO:0005385	zinc ion transmembrane transporter activity	4/2200	27/18639	0.148148148148148	1.25515151515151	0.396988221362675	0.867959806540018
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/2200	27/18639	0.148148148148148	1.25515151515151	0.396988221362675	0.867959806540018
GO:0005496	steroid binding	14/2200	108/18639	0.12962962962963	1.09825757575758	0.397146421981122	0.867959806540018
GO:0008200	ion channel inhibitor activity	6/2200	43/18639	0.13953488372093	1.18217758985201	0.397883908391843	0.867959806540018
GO:0061631	ubiquitin conjugating enzyme activity	5/2200	35/18639	0.142857142857143	1.21032467532468	0.398172980557962	0.867959806540018
GO:0060589	nucleoside-triphosphatase regulator activity	60/2200	490/18639	0.122448979591837	1.03742115027829	0.40042422572505	0.871300110554328
GO:0098631	cell adhesion mediator activity	10/2200	76/18639	0.131578947368421	1.11477272727273	0.408228123897229	0.886689043303658
GO:0004714	transmembrane receptor protein tyrosine kinase activity	8/2200	60/18639	0.133333333333333	1.12963636363636	0.4140791848757	0.888341418353285
GO:0005080	protein kinase C binding	7/2200	52/18639	0.134615384615385	1.14049825174825	0.417027690220039	0.888341418353285
GO:0016248	channel inhibitor activity	6/2200	44/18639	0.136363636363636	1.15530991735537	0.419921321660988	0.888341418353285
GO:0030547	signaling receptor inhibitor activity	6/2200	44/18639	0.136363636363636	1.15530991735537	0.419921321660988	0.888341418353285
GO:0000340	RNA 7-methylguanosine cap binding	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:0005078	MAP-kinase scaffold activity	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:0005095	GTPase inhibitor activity	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:0005165	neurotrophin receptor binding	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:0005527	macrolide binding	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:0035197	siRNA binding	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:0035251	UDP-glucosyltransferase activity	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:0035497	cAMP response element binding	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:0043047	single-stranded telomeric DNA binding	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:0070679	inositol 1,4,5 trisphosphate binding	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:1990459	transferrin receptor binding	2/2200	12/18639	0.166666666666667	1.41204545454545	0.422741081439386	0.888341418353285
GO:0045499	chemorepellent activity	4/2200	28/18639	0.142857142857143	1.21032467532468	0.42487028021985	0.888341418353285
GO:0046625	sphingolipid binding	4/2200	28/18639	0.142857142857143	1.21032467532468	0.42487028021985	0.888341418353285
GO:0051019	mitogen-activated protein kinase binding	4/2200	28/18639	0.142857142857143	1.21032467532468	0.42487028021985	0.888341418353285
GO:0001972	retinoic acid binding	3/2200	20/18639	0.15	1.27084090909091	0.425846835035692	0.888341418353285
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/2200	20/18639	0.15	1.27084090909091	0.425846835035692	0.888341418353285
GO:0052745	inositol phosphate phosphatase activity	3/2200	20/18639	0.15	1.27084090909091	0.425846835035692	0.888341418353285
GO:0008080	N-acetyltransferase activity	9/2200	69/18639	0.130434782608696	1.1050790513834	0.428704236599602	0.892765523640409
GO:1901505	carbohydrate derivative transmembrane transporter activity	7/2200	53/18639	0.132075471698113	1.11897941680961	0.437173969487951	0.908841939998964
GO:0042605	peptide antigen binding	6/2200	45/18639	0.133333333333333	1.12963636363636	0.441850523833063	0.912926330637756
GO:0141110	transporter inhibitor activity	6/2200	45/18639	0.133333333333333	1.12963636363636	0.441850523833063	0.912926330637756
GO:0022829	wide pore channel activity	5/2200	37/18639	0.135135135135135	1.14490171990172	0.446903736563096	0.912926330637756
GO:0008234	cysteine-type peptidase activity	23/2200	187/18639	0.122994652406417	1.04204423918328	0.449988052233908	0.912926330637756
GO:0005096	GTPase activator activity	33/2200	271/18639	0.121771217712177	1.03167896678967	0.452008980502155	0.912926330637756
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	4/2200	29/18639	0.137931034482759	1.16858934169279	0.452413457678202	0.912926330637756
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	4/2200	29/18639	0.137931034482759	1.16858934169279	0.452413457678202	0.912926330637756
GO:0051861	glycolipid binding	4/2200	29/18639	0.137931034482759	1.16858934169279	0.452413457678202	0.912926330637756
GO:0097472	cyclin-dependent protein kinase activity	4/2200	29/18639	0.137931034482759	1.16858934169279	0.452413457678202	0.912926330637756
GO:0008081	phosphoric diester hydrolase activity	11/2200	87/18639	0.126436781609195	1.07120689655172	0.452606964232246	0.912926330637756
GO:0051287	NAD binding	7/2200	54/18639	0.12962962962963	1.09825757575758	0.457211554023165	0.912926330637756
GO:0033293	monocarboxylic acid binding	10/2200	79/18639	0.126582278481013	1.07243958573073	0.457918091842699	0.912926330637756
GO:0005123	death receptor binding	3/2200	21/18639	0.142857142857143	1.21032467532468	0.458442731516859	0.912926330637756
GO:0008373	sialyltransferase activity	3/2200	21/18639	0.142857142857143	1.21032467532468	0.458442731516859	0.912926330637756
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/2200	21/18639	0.142857142857143	1.21032467532468	0.458442731516859	0.912926330637756
GO:0019200	carbohydrate kinase activity	3/2200	21/18639	0.142857142857143	1.21032467532468	0.458442731516859	0.912926330637756
GO:0035613	RNA stem-loop binding	3/2200	21/18639	0.142857142857143	1.21032467532468	0.458442731516859	0.912926330637756
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	3/2200	21/18639	0.142857142857143	1.21032467532468	0.458442731516859	0.912926330637756
GO:0061891	calcium ion sensor activity	3/2200	21/18639	0.142857142857143	1.21032467532468	0.458442731516859	0.912926330637756
GO:0004896	cytokine receptor activity	12/2200	96/18639	0.125	1.05903409090909	0.46265814529691	0.912926330637756
GO:0030291	protein serine/threonine kinase inhibitor activity	6/2200	46/18639	0.130434782608696	1.1050790513834	0.463609896753079	0.912926330637756
GO:0002161	aminoacyl-tRNA editing activity	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0008035	high-density lipoprotein particle binding	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0008417	fucosyltransferase activity	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0030955	potassium ion binding	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0035673	oligopeptide transmembrane transporter activity	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0039706	co-receptor binding	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0045159	myosin II binding	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0070700	BMP receptor binding	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0071837	HMG box domain binding	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0140333	glycerophospholipid flippase activity	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0140666	annealing activity	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0140852	histone ubiquitin ligase activity	2/2200	13/18639	0.153846153846154	1.30342657342657	0.464748800332917	0.912926330637756
GO:0016758	hexosyltransferase activity	24/2200	197/18639	0.121827411167513	1.03215505306876	0.467062095966892	0.915985858109827
GO:0016798	hydrolase activity, acting on glycosyl bonds	16/2200	130/18639	0.123076923076923	1.04274125874126	0.469349999583707	0.917583988474544
GO:1901682	sulfur compound transmembrane transporter activity	8/2200	63/18639	0.126984126984127	1.07584415584416	0.470023770252345	0.917583988474544
GO:0042887	amide transmembrane transporter activity	5/2200	38/18639	0.131578947368421	1.11477272727273	0.470905314217134	0.917583988474544
GO:0043531	ADP binding	5/2200	38/18639	0.131578947368421	1.11477272727273	0.470905314217134	0.917583988474544
GO:0016769	transferase activity, transferring nitrogenous groups	4/2200	30/18639	0.133333333333333	1.12963636363636	0.479509555163508	0.928351164691036
GO:0070566	adenylyltransferase activity	4/2200	30/18639	0.133333333333333	1.12963636363636	0.479509555163508	0.928351164691036
GO:0005516	calmodulin binding	25/2200	207/18639	0.120772946859903	1.02322134387352	0.48337568052403	0.928351164691036
GO:0004713	protein tyrosine kinase activity	17/2200	140/18639	0.121428571428571	1.02877597402597	0.489307223391159	0.928351164691036
GO:0032931	histone H3K56 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0043992	histone H3K9 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0043993	histone H3K18 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0043994	histone H3K23 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0043999	histone H2AK5 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0044012	histone H2AK9 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0044014	histone H2BK5 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0044015	histone H2BK12 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0044016	histone H3K4 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0044017	histone H3K27 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0044018	histone H3K36 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0046972	histone H4K16 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0140784	metal ion sensor activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0140908	histone H3K122 acetyltransferase activity	3/2200	22/18639	0.136363636363636	1.15530991735537	0.490218436800547	0.928351164691036
GO:0000217	DNA secondary structure binding	5/2200	39/18639	0.128205128205128	1.08618881118881	0.494565104098293	0.931389446130004
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	16/2200	132/18639	0.121212121212121	1.02694214876033	0.494985490490339	0.931389446130004
GO:0043539	protein serine/threonine kinase activator activity	9/2200	73/18639	0.123287671232877	1.04452677459527	0.498250488894066	0.931389446130004
GO:0019210	kinase inhibitor activity	11/2200	90/18639	0.122222222222222	1.0355	0.499360935645153	0.931389446130004
GO:0005161	platelet-derived growth factor receptor binding	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0005344	oxygen carrier activity	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0008474	palmitoyl-(protein) hydrolase activity	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0008494	translation activator activity	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0015926	glucosidase activity	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0019992	diacylglycerol binding	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0034236	protein kinase A catalytic subunit binding	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0042043	neurexin family protein binding	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0044548	S100 protein binding	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0098599	palmitoyl hydrolase activity	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0098847	sequence-specific single stranded DNA binding	2/2200	14/18639	0.142857142857143	1.21032467532468	0.504886853223938	0.931389446130004
GO:0072349	modified amino acid transmembrane transporter activity	4/2200	31/18639	0.129032258064516	1.09319648093842	0.506063507434293	0.93214129332882
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	11/2200	91/18639	0.120879120879121	1.02412087912088	0.514733495404921	0.938486228110982
GO:0072341	modified amino acid binding	11/2200	91/18639	0.120879120879121	1.02412087912088	0.514733495404921	0.938486228110982
GO:0003678	DNA helicase activity	9/2200	74/18639	0.121621621621622	1.03041154791155	0.515302610129553	0.938486228110982
GO:0035064	methylated histone binding	9/2200	74/18639	0.121621621621622	1.03041154791155	0.515302610129553	0.938486228110982
GO:0015036	disulfide oxidoreductase activity	5/2200	40/18639	0.125	1.05903409090909	0.517817662112143	0.938486228110982
GO:0061791	GTPase motor activity	5/2200	40/18639	0.125	1.05903409090909	0.517817662112143	0.938486228110982
GO:0071949	FAD binding	5/2200	40/18639	0.125	1.05903409090909	0.517817662112143	0.938486228110982
GO:1990606	membrane scission GTPase motor activity	5/2200	40/18639	0.125	1.05903409090909	0.517817662112143	0.938486228110982
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/2200	23/18639	0.130434782608696	1.1050790513834	0.521046861833257	0.938486228110982
GO:0031681	G-protein beta-subunit binding	3/2200	23/18639	0.130434782608696	1.1050790513834	0.521046861833257	0.938486228110982
GO:0044013	histone H2B acetyltransferase activity	3/2200	23/18639	0.130434782608696	1.1050790513834	0.521046861833257	0.938486228110982
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/2200	23/18639	0.130434782608696	1.1050790513834	0.521046861833257	0.938486228110982
GO:0030165	PDZ domain binding	10/2200	83/18639	0.120481927710843	1.02075575027382	0.522999940198357	0.938486228110982
GO:0005004	GPI-linked ephrin receptor activity	6/2200	49/18639	0.122448979591837	1.03742115027829	0.527317756884141	0.938486228110982
GO:0005008	hepatocyte growth factor receptor activity	6/2200	49/18639	0.122448979591837	1.03742115027829	0.527317756884141	0.938486228110982
GO:0005009	insulin receptor activity	6/2200	49/18639	0.122448979591837	1.03742115027829	0.527317756884141	0.938486228110982
GO:0005011	macrophage colony-stimulating factor receptor activity	6/2200	49/18639	0.122448979591837	1.03742115027829	0.527317756884141	0.938486228110982
GO:0005018	platelet-derived growth factor alpha-receptor activity	6/2200	49/18639	0.122448979591837	1.03742115027829	0.527317756884141	0.938486228110982
GO:0005020	stem cell factor receptor activity	6/2200	49/18639	0.122448979591837	1.03742115027829	0.527317756884141	0.938486228110982
GO:0008288	boss receptor activity	6/2200	49/18639	0.122448979591837	1.03742115027829	0.527317756884141	0.938486228110982
GO:0036332	placental growth factor receptor activity	6/2200	49/18639	0.122448979591837	1.03742115027829	0.527317756884141	0.938486228110982
GO:0038062	protein tyrosine kinase collagen receptor activity	6/2200	49/18639	0.122448979591837	1.03742115027829	0.527317756884141	0.938486228110982
GO:0060175	brain-derived neurotrophic factor receptor activity	6/2200	49/18639	0.122448979591837	1.03742115027829	0.527317756884141	0.938486228110982
GO:0003725	double-stranded RNA binding	9/2200	75/18639	0.12	1.01667272727273	0.532165267990246	0.94423189783261
GO:0017116	single-stranded DNA helicase activity	7/2200	58/18639	0.120689655172414	1.02251567398119	0.535387729396958	0.94423189783261
GO:0004860	protein kinase inhibitor activity	10/2200	84/18639	0.119047619047619	1.0086038961039	0.538895851168075	0.94423189783261
GO:0004812	aminoacyl-tRNA ligase activity	5/2200	41/18639	0.121951219512195	1.03320399113082	0.540604727226707	0.94423189783261
GO:0016875	ligase activity, forming carbon-oxygen bonds	5/2200	41/18639	0.121951219512195	1.03320399113082	0.540604727226707	0.94423189783261
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	8/2200	67/18639	0.119402985074627	1.01161465400271	0.542466054834362	0.94423189783261
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/2200	15/18639	0.133333333333333	1.12963636363636	0.543011248176014	0.94423189783261
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/2200	15/18639	0.133333333333333	1.12963636363636	0.543011248176014	0.94423189783261
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/2200	15/18639	0.133333333333333	1.12963636363636	0.543011248176014	0.94423189783261
GO:0008252	nucleotidase activity	2/2200	15/18639	0.133333333333333	1.12963636363636	0.543011248176014	0.94423189783261
GO:0015929	hexosaminidase activity	2/2200	15/18639	0.133333333333333	1.12963636363636	0.543011248176014	0.94423189783261
GO:0017081	chloride channel regulator activity	2/2200	15/18639	0.133333333333333	1.12963636363636	0.543011248176014	0.94423189783261
GO:0045504	dynein heavy chain binding	2/2200	15/18639	0.133333333333333	1.12963636363636	0.543011248176014	0.94423189783261
GO:0047372	monoacylglycerol lipase activity	2/2200	15/18639	0.133333333333333	1.12963636363636	0.543011248176014	0.94423189783261
GO:0061578	K63-linked deubiquitinase activity	2/2200	15/18639	0.133333333333333	1.12963636363636	0.543011248176014	0.94423189783261
GO:0120283	protein serine/threonine kinase binding	2/2200	15/18639	0.133333333333333	1.12963636363636	0.543011248176014	0.94423189783261
GO:0016791	phosphatase activity	32/2200	273/18639	0.117216117216117	0.993086913086913	0.54516187430833	0.945893474101115
GO:0005007	fibroblast growth factor receptor activity	6/2200	50/18639	0.12	1.01667272727273	0.547868992424903	0.945893474101115
GO:0005017	platelet-derived growth factor receptor activity	6/2200	50/18639	0.12	1.01667272727273	0.547868992424903	0.945893474101115
GO:0005019	platelet-derived growth factor beta-receptor activity	6/2200	50/18639	0.12	1.01667272727273	0.547868992424903	0.945893474101115
GO:0015605	organophosphate ester transmembrane transporter activity	6/2200	50/18639	0.12	1.01667272727273	0.547868992424903	0.945893474101115
GO:0140034	methylation-dependent protein binding	9/2200	76/18639	0.118421052631579	1.00329545454545	0.548813541077367	0.946176403678192
GO:0030215	semaphorin receptor binding	3/2200	24/18639	0.125	1.05903409090909	0.550826554529957	0.94695288523448
GO:0043998	histone H2A acetyltransferase activity	3/2200	24/18639	0.125	1.05903409090909	0.550826554529957	0.94695288523448
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	4/2200	33/18639	0.121212121212121	1.02694214876033	0.55722815374955	0.956601306436905
GO:0051879	Hsp90 protein binding	5/2200	42/18639	0.119047619047619	1.0086038961039	0.562875104151924	0.964928749974727
GO:0005021	vascular endothelial growth factor receptor activity	6/2200	51/18639	0.117647058823529	0.996737967914439	0.568008591512225	0.970982246703549
GO:0005030	neurotrophin receptor activity	6/2200	51/18639	0.117647058823529	0.996737967914439	0.568008591512225	0.970982246703549
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/2200	16/18639	0.125	1.05903409090909	0.57903799428028	0.972187706995858
GO:0004708	MAP kinase kinase activity	2/2200	16/18639	0.125	1.05903409090909	0.57903799428028	0.972187706995858
GO:0005149	interleukin-1 receptor binding	2/2200	16/18639	0.125	1.05903409090909	0.57903799428028	0.972187706995858
GO:0008142	oxysterol binding	2/2200	16/18639	0.125	1.05903409090909	0.57903799428028	0.972187706995858
GO:0019841	retinol binding	2/2200	16/18639	0.125	1.05903409090909	0.57903799428028	0.972187706995858
GO:0022841	potassium ion leak channel activity	2/2200	16/18639	0.125	1.05903409090909	0.57903799428028	0.972187706995858
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/2200	16/18639	0.125	1.05903409090909	0.57903799428028	0.972187706995858
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/2200	16/18639	0.125	1.05903409090909	0.57903799428028	0.972187706995858
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/2200	16/18639	0.125	1.05903409090909	0.57903799428028	0.972187706995858
GO:0140327	flippase activity	2/2200	16/18639	0.125	1.05903409090909	0.57903799428028	0.972187706995858
GO:0140328	floppase activity	2/2200	16/18639	0.125	1.05903409090909	0.57903799428028	0.972187706995858
GO:0008483	transaminase activity	3/2200	25/18639	0.12	1.01667272727273	0.579479282956853	0.972187706995858
GO:0015271	outward rectifier potassium channel activity	3/2200	25/18639	0.12	1.01667272727273	0.579479282956853	0.972187706995858
GO:0042578	phosphoric ester hydrolase activity	42/2200	363/18639	0.115702479338843	0.980262960180316	0.579943656896044	0.972187706995858
GO:0015035	protein-disulfide reductase activity	4/2200	34/18639	0.117647058823529	0.996737967914439	0.581710529638238	0.972459533684889
GO:0016831	carboxy-lyase activity	4/2200	34/18639	0.117647058823529	0.996737967914439	0.581710529638238	0.972459533684889
GO:0008375	acetylglucosaminyltransferase activity	5/2200	43/18639	0.116279069767442	0.98514799154334	0.584584472015092	0.975917878901229
GO:0031072	heat shock protein binding	15/2200	131/18639	0.114503816793893	0.970107564191534	0.590550637403567	0.98452183292039
GO:0008013	beta-catenin binding	12/2200	106/18639	0.113207547169811	0.959125214408233	0.606366030017075	0.995790519886949
GO:0005003	ephrin receptor activity	6/2200	53/18639	0.113207547169811	0.959125214408233	0.606918065281705	0.995790519886949
GO:0005005	transmembrane-ephrin receptor activity	6/2200	53/18639	0.113207547169811	0.959125214408233	0.606918065281705	0.995790519886949
GO:0005246	calcium channel regulator activity	6/2200	53/18639	0.113207547169811	0.959125214408233	0.606918065281705	0.995790519886949
GO:0038064	collagen receptor activity	6/2200	53/18639	0.113207547169811	0.959125214408233	0.606918065281705	0.995790519886949
GO:0030247	polysaccharide binding	3/2200	26/18639	0.115384615384615	0.97756993006993	0.606947612228903	0.995790519886949
GO:0034237	protein kinase A regulatory subunit binding	3/2200	26/18639	0.115384615384615	0.97756993006993	0.606947612228903	0.995790519886949
GO:0043548	phosphatidylinositol 3-kinase binding	3/2200	26/18639	0.115384615384615	0.97756993006993	0.606947612228903	0.995790519886949
GO:0052742	phosphatidylinositol kinase activity	3/2200	26/18639	0.115384615384615	0.97756993006993	0.606947612228903	0.995790519886949
GO:0070412	R-SMAD binding	3/2200	26/18639	0.115384615384615	0.97756993006993	0.606947612228903	0.995790519886949
GO:0035401	histone H3Y41 kinase activity	13/2200	115/18639	0.11304347826087	0.957735177865613	0.609272546207613	0.995790519886949
GO:0140801	histone H2AXY142 kinase activity	13/2200	115/18639	0.11304347826087	0.957735177865613	0.609272546207613	0.995790519886949
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/2200	17/18639	0.117647058823529	0.996737967914439	0.612930954154991	0.995790519886949
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/2200	17/18639	0.117647058823529	0.996737967914439	0.612930954154991	0.995790519886949
GO:0008429	phosphatidylethanolamine binding	2/2200	17/18639	0.117647058823529	0.996737967914439	0.612930954154991	0.995790519886949
GO:0019198	transmembrane receptor protein phosphatase activity	2/2200	17/18639	0.117647058823529	0.996737967914439	0.612930954154991	0.995790519886949
GO:0032183	SUMO binding	2/2200	17/18639	0.117647058823529	0.996737967914439	0.612930954154991	0.995790519886949
GO:0048038	quinone binding	2/2200	17/18639	0.117647058823529	0.996737967914439	0.612930954154991	0.995790519886949
GO:0070492	oligosaccharide binding	2/2200	17/18639	0.117647058823529	0.996737967914439	0.612930954154991	0.995790519886949
GO:0005543	phospholipid binding	57/2200	497/18639	0.114688128772636	0.971669105542345	0.613742176861015	0.995790519886949
GO:0046982	protein heterodimerization activity	42/2200	369/18639	0.113821138211382	0.964323725055432	0.624294363114662	0.999999999999861
GO:0004715	non-membrane spanning protein tyrosine kinase activity	5/2200	45/18639	0.111111111111111	0.941363636363636	0.62617570837738	0.999999999999861
GO:0051539	4 iron, 4 sulfur cluster binding	5/2200	45/18639	0.111111111111111	0.941363636363636	0.62617570837738	0.999999999999861
GO:0005525	GTP binding	43/2200	378/18639	0.113756613756614	0.963777056277056	0.626726312624512	0.999999999999861
GO:0001618	virus receptor activity	9/2200	81/18639	0.111111111111111	0.941363636363636	0.62809011952271	0.999999999999861
GO:0033192	calmodulin-dependent protein phosphatase activity	9/2200	81/18639	0.111111111111111	0.941363636363636	0.62809011952271	0.999999999999861
GO:0140791	histone H2AXS140 phosphatase activity	9/2200	81/18639	0.111111111111111	0.941363636363636	0.62809011952271	0.999999999999861
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	9/2200	81/18639	0.111111111111111	0.941363636363636	0.62809011952271	0.999999999999861
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	9/2200	81/18639	0.111111111111111	0.941363636363636	0.62809011952271	0.999999999999861
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	9/2200	81/18639	0.111111111111111	0.941363636363636	0.62809011952271	0.999999999999861
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	9/2200	81/18639	0.111111111111111	0.941363636363636	0.62809011952271	0.999999999999861
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	9/2200	81/18639	0.111111111111111	0.941363636363636	0.62809011952271	0.999999999999861
GO:1990439	MAP kinase serine/threonine phosphatase activity	9/2200	81/18639	0.111111111111111	0.941363636363636	0.62809011952271	0.999999999999861
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/2200	36/18639	0.111111111111111	0.941363636363636	0.628237764872224	0.999999999999861
GO:0004843	cysteine-type deubiquitinase activity	12/2200	108/18639	0.111111111111111	0.941363636363636	0.632944078056532	0.999999999999861
GO:0001671	ATPase activator activity	3/2200	27/18639	0.111111111111111	0.941363636363636	0.633192536087182	0.999999999999861
GO:0015297	antiporter activity	15/2200	135/18639	0.111111111111111	0.941363636363636	0.63853794416191	0.999999999999861
GO:0004521	RNA endonuclease activity	8/2200	73/18639	0.10958904109589	0.928468244084682	0.642680088738061	0.999999999999861
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	9/2200	82/18639	0.109756097560976	0.929883592017738	0.643027516166876	0.999999999999861
GO:0033549	MAP kinase phosphatase activity	9/2200	82/18639	0.109756097560976	0.929883592017738	0.643027516166876	0.999999999999861
GO:0140272	exogenous protein binding	9/2200	82/18639	0.109756097560976	0.929883592017738	0.643027516166876	0.999999999999861
GO:0098632	cell-cell adhesion mediator activity	6/2200	55/18639	0.109090909090909	0.924247933884297	0.643819643946931	0.999999999999861
GO:0015280	ligand-gated sodium channel activity	2/2200	18/18639	0.111111111111111	0.941363636363636	0.644691726160879	0.999999999999861
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/2200	18/18639	0.111111111111111	0.941363636363636	0.644691726160879	0.999999999999861
GO:0140789	histone phosphatase activity	15/2200	136/18639	0.110294117647059	0.934441844919786	0.650083212363429	0.999999999999861
GO:0008194	UDP-glycosyltransferase activity	16/2200	145/18639	0.110344827586207	0.934871473354232	0.651628428178858	0.999999999999861
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	9/2200	83/18639	0.108433734939759	0.91868017524644	0.65762546459548	0.999999999999861
GO:0051959	dynein light intermediate chain binding	3/2200	28/18639	0.107142857142857	0.907743506493506	0.658191206791261	0.999999999999861
GO:0004222	metalloendopeptidase activity	12/2200	110/18639	0.109090909090909	0.924247933884297	0.658571305177853	0.999999999999861
GO:0038024	cargo receptor activity	7/2200	65/18639	0.107692307692308	0.912398601398601	0.659295784773278	0.999999999999861
GO:0120013	lipid transfer activity	7/2200	65/18639	0.107692307692308	0.912398601398601	0.659295784773278	0.999999999999861
GO:0003924	GTPase activity	37/2200	331/18639	0.11178247734139	0.947051634166438	0.664307321818552	0.999999999999861
GO:0005504	fatty acid binding	5/2200	47/18639	0.106382978723404	0.901305609284333	0.665150654789998	0.999999999999861
GO:0017018	myosin phosphatase activity	9/2200	84/18639	0.107142857142857	0.907743506493506	0.671873018206768	0.999999999999861
GO:0051015	actin filament binding	23/2200	209/18639	0.110047846889952	0.932355371900827	0.672248337101033	0.999999999999861
GO:0003756	protein disulfide isomerase activity	2/2200	19/18639	0.105263157894737	0.891818181818182	0.674351246739317	0.999999999999861
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/2200	19/18639	0.105263157894737	0.891818181818182	0.674351246739317	0.999999999999861
GO:0008301	DNA binding, bending	2/2200	19/18639	0.105263157894737	0.891818181818182	0.674351246739317	0.999999999999861
GO:0008574	plus-end-directed microtubule motor activity	2/2200	19/18639	0.105263157894737	0.891818181818182	0.674351246739317	0.999999999999861
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/2200	19/18639	0.105263157894737	0.891818181818182	0.674351246739317	0.999999999999861
GO:0022840	leak channel activity	2/2200	19/18639	0.105263157894737	0.891818181818182	0.674351246739317	0.999999999999861
GO:0022842	narrow pore channel activity	2/2200	19/18639	0.105263157894737	0.891818181818182	0.674351246739317	0.999999999999861
GO:0031420	alkali metal ion binding	2/2200	19/18639	0.105263157894737	0.891818181818182	0.674351246739317	0.999999999999861
GO:0034987	immunoglobulin receptor binding	2/2200	19/18639	0.105263157894737	0.891818181818182	0.674351246739317	0.999999999999861
GO:0046624	sphingolipid transporter activity	2/2200	19/18639	0.105263157894737	0.891818181818182	0.674351246739317	0.999999999999861
GO:0050145	nucleoside monophosphate kinase activity	2/2200	19/18639	0.105263157894737	0.891818181818182	0.674351246739317	0.999999999999861
GO:1990380	K48-linked deubiquitinase activity	2/2200	19/18639	0.105263157894737	0.891818181818182	0.674351246739317	0.999999999999861
GO:0004629	phospholipase C activity	3/2200	29/18639	0.103448275862069	0.876442006269592	0.681934793227384	0.999999999999861
GO:0099604	ligand-gated calcium channel activity	3/2200	29/18639	0.103448275862069	0.876442006269592	0.681934793227384	0.999999999999861
GO:0140101	catalytic activity, acting on a tRNA	15/2200	139/18639	0.107913669064748	0.914274035317201	0.683525367923176	0.999999999999861
GO:0004722	protein serine/threonine phosphatase activity	11/2200	103/18639	0.106796116504854	0.904805825242718	0.683602981039945	0.999999999999861
GO:0032266	phosphatidylinositol-3-phosphate binding	5/2200	48/18639	0.104166666666667	0.882528409090909	0.683610710469951	0.999999999999861
GO:0036121	double-stranded DNA helicase activity	5/2200	48/18639	0.104166666666667	0.882528409090909	0.683610710469951	0.999999999999861
GO:0004721	phosphoprotein phosphatase activity	19/2200	175/18639	0.108571428571429	0.919846753246753	0.686169849345701	0.999999999999861
GO:0008237	metallopeptidase activity	20/2200	184/18639	0.108695652173913	0.920899209486166	0.687057366753509	0.999999999999861
GO:0016500	protein-hormone receptor activity	7/2200	67/18639	0.104477611940299	0.885162822252374	0.690759765343945	0.999999999999861
GO:0016776	phosphotransferase activity, phosphate group as acceptor	4/2200	39/18639	0.102564102564103	0.868951048951049	0.691512999844017	0.999999999999861
GO:0042288	MHC class I protein binding	2/2200	20/18639	0.1	0.847227272727273	0.701962848039719	0.999999999999861
GO:0001965	G-protein alpha-subunit binding	3/2200	30/18639	0.1	0.847227272727273	0.704426486345592	0.999999999999861
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/2200	30/18639	0.1	0.847227272727273	0.704426486345592	0.999999999999861
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/2200	30/18639	0.1	0.847227272727273	0.704426486345592	0.999999999999861
GO:0032452	histone demethylase activity	3/2200	30/18639	0.1	0.847227272727273	0.704426486345592	0.999999999999861
GO:0033612	receptor serine/threonine kinase binding	3/2200	30/18639	0.1	0.847227272727273	0.704426486345592	0.999999999999861
GO:0048019	receptor antagonist activity	3/2200	30/18639	0.1	0.847227272727273	0.704426486345592	0.999999999999861
GO:0005126	cytokine receptor binding	30/2200	275/18639	0.109090909090909	0.924247933884297	0.705670457024598	0.999999999999861
GO:0005548	phospholipid transporter activity	7/2200	68/18639	0.102941176470588	0.872145721925134	0.705767655585076	0.999999999999861
GO:0030145	manganese ion binding	7/2200	68/18639	0.102941176470588	0.872145721925134	0.705767655585076	0.999999999999861
GO:0004177	aminopeptidase activity	4/2200	40/18639	0.1	0.847227272727273	0.710812481814226	0.999999999999861
GO:0032451	demethylase activity	4/2200	40/18639	0.1	0.847227272727273	0.710812481814226	0.999999999999861
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	4/2200	40/18639	0.1	0.847227272727273	0.710812481814226	0.999999999999861
GO:0050997	quaternary ammonium group binding	4/2200	40/18639	0.1	0.847227272727273	0.710812481814226	0.999999999999861
GO:0036002	pre-mRNA binding	6/2200	59/18639	0.101694915254237	0.861587057010786	0.711014032980862	0.999999999999861
GO:0019001	guanyl nucleotide binding	44/2200	400/18639	0.11	0.93195	0.715265995456898	0.999999999999861
GO:0032561	guanyl ribonucleotide binding	44/2200	400/18639	0.11	0.93195	0.715265995456898	0.999999999999861
GO:0000182	rDNA binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0004935	adrenergic receptor activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0004955	prostaglandin receptor activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0005131	growth hormone receptor binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0005345	purine nucleobase transmembrane transporter activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0005522	profilin binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0008140	cAMP response element binding protein binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0008190	eukaryotic initiation factor 4E binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0015203	polyamine transmembrane transporter activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0016868	intramolecular phosphotransferase activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0019531	oxalate transmembrane transporter activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0031419	cobalamin binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0031996	thioesterase binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0032052	bile acid binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0032356	oxidized DNA binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0035256	G protein-coupled glutamate receptor binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0042975	peroxisome proliferator activated receptor binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0043208	glycosphingolipid binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0043422	protein kinase B binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0050815	phosphoserine residue binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0051864	histone H3K36 demethylase activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0051880	G-quadruplex DNA binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0070097	delta-catenin binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0070739	protein-glutamic acid ligase activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0070740	tubulin-glutamic acid ligase activity	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:1990763	arrestin family protein binding	1/2200	10/18639	0.1	0.847227272727273	0.71529997861274	0.999999999999861
GO:0101005	deubiquitinase activity	12/2200	115/18639	0.104347826086957	0.884063241106719	0.718067318975078	0.999999999999861
GO:0005310	dicarboxylic acid transmembrane transporter activity	3/2200	31/18639	0.0967741935483871	0.819897360703812	0.725679662657517	0.999999999999861
GO:0008327	methyl-CpG binding	3/2200	31/18639	0.0967741935483871	0.819897360703812	0.725679662657517	0.999999999999861
GO:0016878	acid-thiol ligase activity	3/2200	31/18639	0.0967741935483871	0.819897360703812	0.725679662657517	0.999999999999861
GO:0140457	protein demethylase activity	3/2200	31/18639	0.0967741935483871	0.819897360703812	0.725679662657517	0.999999999999861
GO:0005248	voltage-gated sodium channel activity	2/2200	21/18639	0.0952380952380952	0.806883116883117	0.72759654451581	0.999999999999861
GO:0010314	phosphatidylinositol-5-phosphate binding	2/2200	21/18639	0.0952380952380952	0.806883116883117	0.72759654451581	0.999999999999861
GO:0051428	peptide hormone receptor binding	2/2200	21/18639	0.0952380952380952	0.806883116883117	0.72759654451581	0.999999999999861
GO:0001217	DNA-binding transcription repressor activity	30/2200	278/18639	0.107913669064748	0.914274035317201	0.72774519612121	0.999999999999861
GO:0001530	lipopolysaccharide binding	4/2200	41/18639	0.0975609756097561	0.826563192904656	0.729213320148012	0.999999999999861
GO:0001727	lipid kinase activity	4/2200	41/18639	0.0975609756097561	0.826563192904656	0.729213320148012	0.999999999999861
GO:0016877	ligase activity, forming carbon-sulfur bonds	4/2200	41/18639	0.0975609756097561	0.826563192904656	0.729213320148012	0.999999999999861
GO:0042287	MHC protein binding	4/2200	41/18639	0.0975609756097561	0.826563192904656	0.729213320148012	0.999999999999861
GO:0005272	sodium channel activity	5/2200	51/18639	0.0980392156862745	0.830614973262032	0.734776918335191	0.999999999999861
GO:0005506	iron ion binding	16/2200	154/18639	0.103896103896104	0.880236127508855	0.743353861413691	0.999999999999861
GO:0004175	endopeptidase activity	44/2200	405/18639	0.108641975308642	0.920444444444445	0.745199333414362	0.999999999999861
GO:0042910	xenobiotic transmembrane transporter activity	3/2200	32/18639	0.09375	0.794275568181818	0.745716210101155	0.999999999999861
GO:0120015	sterol transfer activity	3/2200	32/18639	0.09375	0.794275568181818	0.745716210101155	0.999999999999861
GO:0044325	transmembrane transporter binding	14/2200	136/18639	0.102941176470588	0.872145721925134	0.746155885580789	0.999999999999861
GO:0019783	ubiquitin-like protein peptidase activity	13/2200	127/18639	0.102362204724409	0.867240515390122	0.748070911289405	0.999999999999861
GO:0000099	sulfur amino acid transmembrane transporter activity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0004954	prostanoid receptor activity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0005114	type II transforming growth factor beta receptor binding	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0005225	volume-sensitive anion channel activity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0008046	axon guidance receptor activity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0008199	ferric iron binding	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0008526	phosphatidylinositol transfer activity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0015205	nucleobase transmembrane transporter activity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0015217	ADP transmembrane transporter activity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0019215	intermediate filament binding	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0032794	GTPase activating protein binding	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0034713	type I transforming growth factor beta receptor binding	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0047676	arachidonate-CoA ligase activity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0097493	structural molecule activity conferring elasticity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0140031	phosphorylation-dependent protein binding	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0180030	inositol phosphate kinase activity	1/2200	11/18639	0.0909090909090909	0.770206611570248	0.748921753643712	0.999999999999861
GO:0005243	gap junction channel activity	2/2200	22/18639	0.0909090909090909	0.770206611570248	0.751334355287336	0.999999999999861
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	2/2200	22/18639	0.0909090909090909	0.770206611570248	0.751334355287336	0.999999999999861
GO:0031683	G-protein beta/gamma-subunit complex binding	2/2200	22/18639	0.0909090909090909	0.770206611570248	0.751334355287336	0.999999999999861
GO:0033691	sialic acid binding	2/2200	22/18639	0.0909090909090909	0.770206611570248	0.751334355287336	0.999999999999861
GO:0030296	protein tyrosine kinase activator activity	3/2200	33/18639	0.0909090909090909	0.770206611570248	0.764565015736315	0.999999999999861
GO:0005544	calcium-dependent phospholipid binding	5/2200	53/18639	0.0943396226415094	0.799271012006861	0.765371665409905	0.999999999999861
GO:0035091	phosphatidylinositol binding	30/2200	284/18639	0.105633802816901	0.894958386683739	0.768837095451342	0.999999999999861
GO:0000295	adenine nucleotide transmembrane transporter activity	2/2200	23/18639	0.0869565217391304	0.736719367588933	0.773266497521058	0.999999999999861
GO:0003887	DNA-directed DNA polymerase activity	2/2200	23/18639	0.0869565217391304	0.736719367588933	0.773266497521058	0.999999999999861
GO:0005212	structural constituent of eye lens	2/2200	23/18639	0.0869565217391304	0.736719367588933	0.773266497521058	0.999999999999861
GO:0070577	lysine-acetylated histone binding	2/2200	23/18639	0.0869565217391304	0.736719367588933	0.773266497521058	0.999999999999861
GO:0140103	catalytic activity, acting on a glycoprotein	2/2200	23/18639	0.0869565217391304	0.736719367588933	0.773266497521058	0.999999999999861
GO:0003720	telomerase activity	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0004300	enoyl-CoA hydratase activity	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0005049	nuclear export signal receptor activity	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0005247	voltage-gated chloride channel activity	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0008179	adenylate cyclase binding	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0008504	monoamine transmembrane transporter activity	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0008603	cAMP-dependent protein kinase regulator activity	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0015132	prostaglandin transmembrane transporter activity	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0015368	calcium:monoatomic cation antiporter activity	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0017166	vinculin binding	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0034452	dynactin binding	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0035259	nuclear glucocorticoid receptor binding	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0042301	phosphate ion binding	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0045295	gamma-catenin binding	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:1990817	poly(A) RNA polymerase activity	1/2200	12/18639	0.0833333333333333	0.706022727272727	0.778574542025923	0.999999999999861
GO:0140463	chromatin-protein adaptor activity	5/2200	54/18639	0.0925925925925926	0.784469696969697	0.779630878289587	0.999999999999861
GO:0015020	glucuronosyltransferase activity	3/2200	34/18639	0.0882352941176471	0.747553475935829	0.782260611165161	0.999999999999861
GO:0030332	cyclin binding	3/2200	34/18639	0.0882352941176471	0.747553475935829	0.782260611165161	0.999999999999861
GO:0051427	hormone receptor binding	3/2200	34/18639	0.0882352941176471	0.747553475935829	0.782260611165161	0.999999999999861
GO:0052866	phosphatidylinositol phosphate phosphatase activity	3/2200	34/18639	0.0882352941176471	0.747553475935829	0.782260611165161	0.999999999999861
GO:0005540	hyaluronic acid binding	2/2200	24/18639	0.0833333333333333	0.706022727272727	0.793488310520249	0.999999999999861
GO:0015149	hexose transmembrane transporter activity	2/2200	24/18639	0.0833333333333333	0.706022727272727	0.793488310520249	0.999999999999861
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/2200	24/18639	0.0833333333333333	0.706022727272727	0.793488310520249	0.999999999999861
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/2200	24/18639	0.0833333333333333	0.706022727272727	0.793488310520249	0.999999999999861
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/2200	24/18639	0.0833333333333333	0.706022727272727	0.793488310520249	0.999999999999861
GO:0055056	D-glucose transmembrane transporter activity	2/2200	24/18639	0.0833333333333333	0.706022727272727	0.793488310520249	0.999999999999861
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/2200	24/18639	0.0833333333333333	0.706022727272727	0.793488310520249	0.999999999999861
GO:0140033	acetylation-dependent protein binding	2/2200	24/18639	0.0833333333333333	0.706022727272727	0.793488310520249	0.999999999999861
GO:0005154	epidermal growth factor receptor binding	3/2200	35/18639	0.0857142857142857	0.726194805194805	0.798841969021048	0.999999999999861
GO:0034061	DNA polymerase activity	3/2200	35/18639	0.0857142857142857	0.726194805194805	0.798841969021048	0.999999999999861
GO:0003964	RNA-directed DNA polymerase activity	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0005172	vascular endothelial growth factor receptor binding	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0008253	5'-nucleotidase activity	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0009982	pseudouridine synthase activity	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0019104	DNA N-glycosylase activity	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0019855	calcium channel inhibitor activity	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0032396	inhibitory MHC class I receptor activity	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0035325	Toll-like receptor binding	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0046974	histone H3K9 methyltransferase activity	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0046975	histone H3K36 methyltransferase activity	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0051011	microtubule minus-end binding	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0061459	L-arginine transmembrane transporter activity	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0071714	icosanoid transmembrane transporter activity	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:1901338	catecholamine binding	1/2200	13/18639	0.0769230769230769	0.651713286713287	0.804726687167007	0.999999999999861
GO:0170055	lipid transmembrane transporter activity	5/2200	56/18639	0.0892857142857143	0.756452922077922	0.80612840119676	0.999999999999861
GO:0008235	metalloexopeptidase activity	6/2200	66/18639	0.0909090909090909	0.770206611570248	0.806423371590664	0.999999999999861
GO:0017124	SH3 domain binding	11/2200	115/18639	0.0956521739130435	0.810391304347826	0.811749264081519	0.999999999999861
GO:0005537	D-mannose binding	2/2200	25/18639	0.08	0.677781818181818	0.812097791177936	0.999999999999861
GO:0015662	P-type ion transporter activity	2/2200	25/18639	0.08	0.677781818181818	0.812097791177936	0.999999999999861
GO:0017025	TBP-class protein binding	2/2200	25/18639	0.08	0.677781818181818	0.812097791177936	0.999999999999861
GO:0120020	cholesterol transfer activity	2/2200	25/18639	0.08	0.677781818181818	0.812097791177936	0.999999999999861
GO:0140358	P-type transmembrane transporter activity	2/2200	25/18639	0.08	0.677781818181818	0.812097791177936	0.999999999999861
GO:0004033	aldo-keto reductase (NADPH) activity	3/2200	36/18639	0.0833333333333333	0.706022727272727	0.814351442125487	0.999999999999861
GO:0045505	dynein intermediate chain binding	3/2200	36/18639	0.0833333333333333	0.706022727272727	0.814351442125487	0.999999999999861
GO:0061749	forked DNA-dependent helicase activity	4/2200	47/18639	0.0851063829787234	0.721044487427466	0.821439067905526	0.999999999999861
GO:1990518	single-stranded 3'-5' DNA helicase activity	4/2200	47/18639	0.0851063829787234	0.721044487427466	0.821439067905526	0.999999999999861
GO:0004065	arylsulfatase activity	1/2200	14/18639	0.0714285714285714	0.605162337662338	0.827791289778012	0.999999999999861
GO:0004705	JUN kinase activity	1/2200	14/18639	0.0714285714285714	0.605162337662338	0.827791289778012	0.999999999999861
GO:0005347	ATP transmembrane transporter activity	1/2200	14/18639	0.0714285714285714	0.605162337662338	0.827791289778012	0.999999999999861
GO:0030983	mismatched DNA binding	1/2200	14/18639	0.0714285714285714	0.605162337662338	0.827791289778012	0.999999999999861
GO:0032454	histone H3K9 demethylase activity	1/2200	14/18639	0.0714285714285714	0.605162337662338	0.827791289778012	0.999999999999861
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/2200	14/18639	0.0714285714285714	0.605162337662338	0.827791289778012	0.999999999999861
GO:0046030	inositol trisphosphate phosphatase activity	1/2200	14/18639	0.0714285714285714	0.605162337662338	0.827791289778012	0.999999999999861
GO:0071933	Arp2/3 complex binding	1/2200	14/18639	0.0714285714285714	0.605162337662338	0.827791289778012	0.999999999999861
GO:1901612	cardiolipin binding	1/2200	14/18639	0.0714285714285714	0.605162337662338	0.827791289778012	0.999999999999861
GO:0004435	phosphatidylinositol phospholipase C activity	2/2200	26/18639	0.0769230769230769	0.651713286713287	0.829193639423688	0.999999999999861
GO:0005160	transforming growth factor beta receptor binding	2/2200	26/18639	0.0769230769230769	0.651713286713287	0.829193639423688	0.999999999999861
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/2200	26/18639	0.0769230769230769	0.651713286713287	0.829193639423688	0.999999999999861
GO:0015145	monosaccharide transmembrane transporter activity	2/2200	26/18639	0.0769230769230769	0.651713286713287	0.829193639423688	0.999999999999861
GO:0015216	purine nucleotide transmembrane transporter activity	2/2200	26/18639	0.0769230769230769	0.651713286713287	0.829193639423688	0.999999999999861
GO:0019865	immunoglobulin binding	2/2200	26/18639	0.0769230769230769	0.651713286713287	0.829193639423688	0.999999999999861
GO:0051139	metal cation:proton antiporter activity	2/2200	26/18639	0.0769230769230769	0.651713286713287	0.829193639423688	0.999999999999861
GO:0005085	guanyl-nucleotide exchange factor activity	23/2200	230/18639	0.1	0.847227272727273	0.830005986343679	0.999999999999861
GO:0061980	regulatory RNA binding	5/2200	58/18639	0.0862068965517241	0.730368338557994	0.830029696029122	0.999999999999861
GO:0004725	protein tyrosine phosphatase activity	9/2200	98/18639	0.0918367346938776	0.77806586270872	0.831882682727462	0.999999999999861
GO:0009378	four-way junction helicase activity	4/2200	48/18639	0.0833333333333333	0.706022727272727	0.833968918581487	0.999999999999861
GO:0043138	3'-5' DNA helicase activity	4/2200	48/18639	0.0833333333333333	0.706022727272727	0.833968918581487	0.999999999999861
GO:0140375	immune receptor activity	15/2200	156/18639	0.0961538461538462	0.814641608391608	0.835161542678757	0.999999999999861
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	27/2200	268/18639	0.100746268656716	0.85354986431479	0.836090519674622	0.999999999999861
GO:0016835	carbon-oxygen lyase activity	7/2200	79/18639	0.0886075949367089	0.750707710011507	0.838517279656985	0.999999999999861
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	8/2200	89/18639	0.0898876404494382	0.761552604698672	0.839149615442327	0.999999999999861
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	8/2200	89/18639	0.0898876404494382	0.761552604698672	0.839149615442327	0.999999999999861
GO:1901981	phosphatidylinositol phosphate binding	18/2200	185/18639	0.0972972972972973	0.824329238329238	0.839818841181368	0.999999999999861
GO:0001786	phosphatidylserine binding	5/2200	59/18639	0.0847457627118644	0.717989214175655	0.841049664829887	0.999999999999861
GO:0070888	E-box binding	5/2200	59/18639	0.0847457627118644	0.717989214175655	0.841049664829887	0.999999999999861
GO:0000146	microfilament motor activity	3/2200	38/18639	0.0789473684210526	0.668863636363636	0.842335603245526	0.999999999999861
GO:0004620	phospholipase activity	10/2200	109/18639	0.0917431192660551	0.777272727272727	0.842365035247632	0.999999999999861
GO:0004252	serine-type endopeptidase activity	17/2200	176/18639	0.0965909090909091	0.818344524793388	0.842464595730909	0.999999999999861
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/2200	27/18639	0.0740740740740741	0.627575757575757	0.844873727690609	0.999999999999861
GO:0016405	CoA-ligase activity	2/2200	27/18639	0.0740740740740741	0.627575757575757	0.844873727690609	0.999999999999861
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/2200	27/18639	0.0740740740740741	0.627575757575757	0.844873727690609	0.999999999999861
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/2200	27/18639	0.0740740740740741	0.627575757575757	0.844873727690609	0.999999999999861
GO:0060590	ATPase regulator activity	4/2200	49/18639	0.0816326530612245	0.691614100185529	0.845755375932958	0.999999999999861
GO:0140793	histone H2AXY142 phosphatase activity	8/2200	90/18639	0.0888888888888889	0.753090909090909	0.847887729737338	0.999999999999861
GO:0000774	adenyl-nucleotide exchange factor activity	1/2200	15/18639	0.0666666666666667	0.564818181818182	0.848132721321012	0.999999999999861
GO:0004467	long-chain fatty acid-CoA ligase activity	1/2200	15/18639	0.0666666666666667	0.564818181818182	0.848132721321012	0.999999999999861
GO:0004953	icosanoid receptor activity	1/2200	15/18639	0.0666666666666667	0.564818181818182	0.848132721321012	0.999999999999861
GO:0008242	omega peptidase activity	1/2200	15/18639	0.0666666666666667	0.564818181818182	0.848132721321012	0.999999999999861
GO:0015116	sulfate transmembrane transporter activity	1/2200	15/18639	0.0666666666666667	0.564818181818182	0.848132721321012	0.999999999999861
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/2200	15/18639	0.0666666666666667	0.564818181818182	0.848132721321012	0.999999999999861
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/2200	15/18639	0.0666666666666667	0.564818181818182	0.848132721321012	0.999999999999861
GO:0031005	filamin binding	1/2200	15/18639	0.0666666666666667	0.564818181818182	0.848132721321012	0.999999999999861
GO:0050700	CARD domain binding	1/2200	15/18639	0.0666666666666667	0.564818181818182	0.848132721321012	0.999999999999861
GO:0140776	protein-containing complex destabilizing activity	1/2200	15/18639	0.0666666666666667	0.564818181818182	0.848132721321012	0.999999999999861
GO:0016782	transferase activity, transferring sulphur-containing groups	6/2200	70/18639	0.0857142857142857	0.726194805194805	0.848773272828855	0.999999999999861
GO:0070851	growth factor receptor binding	13/2200	139/18639	0.0935251798561151	0.792370830608241	0.849613115191243	0.999999999999861
GO:0140767	enzyme-substrate adaptor activity	13/2200	139/18639	0.0935251798561151	0.792370830608241	0.849613115191243	0.999999999999861
GO:0005125	cytokine activity	23/2200	234/18639	0.0982905982905983	0.832744755244755	0.852523092624257	0.999999999999861
GO:0016298	lipase activity	12/2200	130/18639	0.0923076923076923	0.782055944055944	0.854125984068895	0.999999999999861
GO:0005319	lipid transporter activity	17/2200	178/18639	0.0955056179775281	0.809149642492339	0.854857713132918	0.999999999999861
GO:1902936	phosphatidylinositol bisphosphate binding	10/2200	111/18639	0.0900900900900901	0.763267813267813	0.857760966181958	0.999999999999861
GO:0016866	intramolecular transferase activity	2/2200	28/18639	0.0714285714285714	0.605162337662338	0.859233921605943	0.999999999999861
GO:0051119	sugar transmembrane transporter activity	2/2200	28/18639	0.0714285714285714	0.605162337662338	0.859233921605943	0.999999999999861
GO:0141052	histone H3 demethylase activity	2/2200	28/18639	0.0714285714285714	0.605162337662338	0.859233921605943	0.999999999999861
GO:0099106	ion channel regulator activity	15/2200	160/18639	0.09375	0.794275568181818	0.861328175135486	0.999999999999861
GO:0008238	exopeptidase activity	9/2200	102/18639	0.0882352941176471	0.747553475935829	0.864309617525345	0.999999999999861
GO:0005200	structural constituent of cytoskeleton	10/2200	112/18639	0.0892857142857143	0.756452922077922	0.864998703548095	0.999999999999861
GO:0004707	MAP kinase activity	1/2200	16/18639	0.0625	0.529517045454545	0.866072369790394	0.999999999999861
GO:0030275	LRR domain binding	1/2200	16/18639	0.0625	0.529517045454545	0.866072369790394	0.999999999999861
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/2200	16/18639	0.0625	0.529517045454545	0.866072369790394	0.999999999999861
GO:0055102	lipase inhibitor activity	1/2200	16/18639	0.0625	0.529517045454545	0.866072369790394	0.999999999999861
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	11/2200	122/18639	0.0901639344262295	0.763893442622951	0.866128470405864	0.999999999999861
GO:0016830	carbon-carbon lyase activity	4/2200	51/18639	0.0784313725490196	0.664491978609626	0.867214676619542	0.999999999999861
GO:0030544	Hsp70 protein binding	4/2200	51/18639	0.0784313725490196	0.664491978609626	0.867214676619542	0.999999999999861
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	17/2200	181/18639	0.0939226519337017	0.79573832245103	0.872028859016714	0.999999999999861
GO:0106222	lncRNA binding	2/2200	29/18639	0.0689655172413793	0.584294670846395	0.872367190374726	0.999999999999861
GO:0008083	growth factor activity	15/2200	162/18639	0.0925925925925926	0.784469696969697	0.873141527026839	0.999999999999861
GO:0003774	cytoskeletal motor activity	14/2200	153/18639	0.0915032679738562	0.77524064171123	0.876978109618585	0.999999999999861
GO:0017080	sodium channel regulator activity	3/2200	41/18639	0.0731707317073171	0.619922394678492	0.877432573248902	0.999999999999861
GO:0004550	nucleoside diphosphate kinase activity	1/2200	17/18639	0.0588235294117647	0.498368983957219	0.881893708267607	0.999999999999861
GO:0008484	sulfuric ester hydrolase activity	1/2200	17/18639	0.0588235294117647	0.498368983957219	0.881893708267607	0.999999999999861
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/2200	17/18639	0.0588235294117647	0.498368983957219	0.881893708267607	0.999999999999861
GO:0009881	photoreceptor activity	1/2200	17/18639	0.0588235294117647	0.498368983957219	0.881893708267607	0.999999999999861
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/2200	17/18639	0.0588235294117647	0.498368983957219	0.881893708267607	0.999999999999861
GO:0016018	cyclosporin A binding	1/2200	17/18639	0.0588235294117647	0.498368983957219	0.881893708267607	0.999999999999861
GO:0016805	dipeptidase activity	1/2200	17/18639	0.0588235294117647	0.498368983957219	0.881893708267607	0.999999999999861
GO:0030169	low-density lipoprotein particle binding	1/2200	17/18639	0.0588235294117647	0.498368983957219	0.881893708267607	0.999999999999861
GO:0030548	acetylcholine receptor regulator activity	1/2200	17/18639	0.0588235294117647	0.498368983957219	0.881893708267607	0.999999999999861
GO:0015215	nucleotide transmembrane transporter activity	2/2200	30/18639	0.0666666666666667	0.564818181818182	0.884362954948235	0.999999999999861
GO:0031210	phosphatidylcholine binding	2/2200	30/18639	0.0666666666666667	0.564818181818182	0.884362954948235	0.999999999999861
GO:0019003	GDP binding	6/2200	75/18639	0.08	0.677781818181818	0.890735908494378	0.999999999999861
GO:0003925	G protein activity	4/2200	54/18639	0.0740740740740741	0.627575757575757	0.894569484403352	0.999999999999861
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	4/2200	54/18639	0.0740740740740741	0.627575757575757	0.894569484403352	0.999999999999861
GO:0050661	NADP binding	4/2200	54/18639	0.0740740740740741	0.627575757575757	0.894569484403352	0.999999999999861
GO:0017147	Wnt-protein binding	2/2200	31/18639	0.0645161290322581	0.546598240469208	0.895306630278629	0.999999999999861
GO:0070273	phosphatidylinositol-4-phosphate binding	2/2200	31/18639	0.0645161290322581	0.546598240469208	0.895306630278629	0.999999999999861
GO:0008308	voltage-gated monoatomic anion channel activity	1/2200	18/18639	0.0555555555555556	0.470681818181818	0.895846766038591	0.999999999999861
GO:0008409	5'-3' exonuclease activity	1/2200	18/18639	0.0555555555555556	0.470681818181818	0.895846766038591	0.999999999999861
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2200	18/18639	0.0555555555555556	0.470681818181818	0.895846766038591	0.999999999999861
GO:0017075	syntaxin-1 binding	1/2200	18/18639	0.0555555555555556	0.470681818181818	0.895846766038591	0.999999999999861
GO:0017128	phospholipid scramblase activity	1/2200	18/18639	0.0555555555555556	0.470681818181818	0.895846766038591	0.999999999999861
GO:0030228	lipoprotein particle receptor activity	1/2200	18/18639	0.0555555555555556	0.470681818181818	0.895846766038591	0.999999999999861
GO:0031690	adrenergic receptor binding	1/2200	18/18639	0.0555555555555556	0.470681818181818	0.895846766038591	0.999999999999861
GO:0032393	MHC class I receptor activity	1/2200	18/18639	0.0555555555555556	0.470681818181818	0.895846766038591	0.999999999999861
GO:0034185	apolipoprotein binding	1/2200	18/18639	0.0555555555555556	0.470681818181818	0.895846766038591	0.999999999999861
GO:0099602	neurotransmitter receptor regulator activity	1/2200	18/18639	0.0555555555555556	0.470681818181818	0.895846766038591	0.999999999999861
GO:1901611	phosphatidylglycerol binding	1/2200	18/18639	0.0555555555555556	0.470681818181818	0.895846766038591	0.999999999999861
GO:0004712	protein serine/threonine/tyrosine kinase activity	3/2200	43/18639	0.0697674418604651	0.591088794926004	0.896797313200497	0.999999999999861
GO:0016247	channel regulator activity	15/2200	168/18639	0.0892857142857143	0.756452922077922	0.903856398810024	0.999999999999861
GO:0015106	bicarbonate transmembrane transporter activity	2/2200	32/18639	0.0625	0.529517045454545	0.905279324957128	0.999999999999861
GO:0043425	bHLH transcription factor binding	2/2200	32/18639	0.0625	0.529517045454545	0.905279324957128	0.999999999999861
GO:0071813	lipoprotein particle binding	2/2200	32/18639	0.0625	0.529517045454545	0.905279324957128	0.999999999999861
GO:0071814	protein-lipid complex binding	2/2200	32/18639	0.0625	0.529517045454545	0.905279324957128	0.999999999999861
GO:0005229	intracellularly calcium-gated chloride channel activity	1/2200	19/18639	0.0526315789473684	0.445909090909091	0.908152072666328	0.999999999999861
GO:0030506	ankyrin binding	1/2200	19/18639	0.0526315789473684	0.445909090909091	0.908152072666328	0.999999999999861
GO:0042834	peptidoglycan binding	1/2200	19/18639	0.0526315789473684	0.445909090909091	0.908152072666328	0.999999999999861
GO:0043395	heparan sulfate proteoglycan binding	1/2200	19/18639	0.0526315789473684	0.445909090909091	0.908152072666328	0.999999999999861
GO:0141147	intracellularly calcium-gated channel activity	1/2200	19/18639	0.0526315789473684	0.445909090909091	0.908152072666328	0.999999999999861
GO:0030170	pyridoxal phosphate binding	4/2200	56/18639	0.0714285714285714	0.605162337662338	0.909933759325808	0.999999999999861
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	11/2200	130/18639	0.0846153846153846	0.716884615384615	0.912099262862047	0.999999999999861
GO:0141108	transporter regulator activity	15/2200	170/18639	0.0882352941176471	0.747553475935829	0.912630112892183	0.999999999999861
GO:0003727	single-stranded RNA binding	7/2200	89/18639	0.0786516853932584	0.666358529111338	0.913062985334001	0.999999999999861
GO:0140303	intramembrane lipid transporter activity	3/2200	45/18639	0.0666666666666667	0.564818181818182	0.91336293043539	0.999999999999861
GO:0003777	microtubule motor activity	5/2200	68/18639	0.0735294117647059	0.622961229946524	0.915953508830269	0.999999999999861
GO:0070279	vitamin B6 binding	4/2200	57/18639	0.0701754385964912	0.594545454545455	0.916842319101625	0.999999999999861
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	48/2200	484/18639	0.0991735537190083	0.840225394440271	0.917963503778633	0.999999999999861
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/2200	20/18639	0.05	0.423613636363636	0.919004137120361	0.999999999999861
GO:0005326	neurotransmitter transmembrane transporter activity	1/2200	20/18639	0.05	0.423613636363636	0.919004137120361	0.999999999999861
GO:0016505	peptidase activator activity involved in apoptotic process	1/2200	20/18639	0.05	0.423613636363636	0.919004137120361	0.999999999999861
GO:0030627	pre-mRNA 5'-splice site binding	1/2200	20/18639	0.05	0.423613636363636	0.919004137120361	0.999999999999861
GO:0030742	GTP-dependent protein binding	1/2200	20/18639	0.05	0.423613636363636	0.919004137120361	0.999999999999861
GO:0046906	tetrapyrrole binding	13/2200	152/18639	0.0855263157894737	0.724602272727273	0.920460273694929	0.999999999999861
GO:0020037	heme binding	12/2200	142/18639	0.0845070422535211	0.715966709346991	0.920696927354817	0.999999999999861
GO:0008175	tRNA methyltransferase activity	2/2200	34/18639	0.0588235294117647	0.498368983957219	0.922613733507649	0.999999999999861
GO:0019825	oxygen binding	2/2200	34/18639	0.0588235294117647	0.498368983957219	0.922613733507649	0.999999999999861
GO:0140359	ABC-type transporter activity	3/2200	47/18639	0.0638297872340425	0.5407833655706	0.92747228764493	0.999999999999861
GO:0015174	basic amino acid transmembrane transporter activity	1/2200	21/18639	0.0476190476190476	0.403441558441558	0.928574516750588	0.999999999999861
GO:1904047	S-adenosyl-L-methionine binding	1/2200	21/18639	0.0476190476190476	0.403441558441558	0.928574516750588	0.999999999999861
GO:0008236	serine-type peptidase activity	17/2200	194/18639	0.0876288659793814	0.74241565135895	0.928749623689149	0.999999999999861
GO:0015459	potassium channel regulator activity	4/2200	59/18639	0.0677966101694915	0.574391371340524	0.929252754242301	0.999999999999861
GO:0043015	gamma-tubulin binding	2/2200	35/18639	0.0571428571428571	0.48412987012987	0.930115052567443	0.999999999999861
GO:0140566	histone reader activity	2/2200	35/18639	0.0571428571428571	0.48412987012987	0.930115052567443	0.999999999999861
GO:0140299	molecular sensor activity	5/2200	71/18639	0.0704225352112676	0.596638924455826	0.932864634092474	0.999999999999861
GO:0038187	pattern recognition receptor activity	3/2200	48/18639	0.0625	0.529517045454545	0.933705845582493	0.999999999999861
GO:0001216	DNA-binding transcription activator activity	48/2200	491/18639	0.0977596741344195	0.828246620996112	0.933810892121746	0.999999999999861
GO:0004190	aspartic-type endopeptidase activity	2/2200	36/18639	0.0555555555555556	0.470681818181818	0.936924676711088	0.999999999999861
GO:0140517	protein-RNA adaptor activity	1/2200	22/18639	0.0454545454545455	0.385103305785124	0.937014524439314	0.999999999999861
GO:0016836	hydro-lyase activity	4/2200	61/18639	0.0655737704918033	0.555558867362146	0.939965108411279	0.999999999999861
GO:0017171	serine hydrolase activity	17/2200	198/18639	0.0858585858585859	0.727417355371901	0.941235288780784	0.999999999999861
GO:0070001	aspartic-type peptidase activity	2/2200	37/18639	0.0540540540540541	0.457960687960688	0.943101296191438	0.999999999999861
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/2200	23/18639	0.0434782608695652	0.368359683794466	0.944457616571962	0.999999999999861
GO:0099186	structural constituent of postsynapse	1/2200	23/18639	0.0434782608695652	0.368359683794466	0.944457616571962	0.999999999999861
GO:0048020	CCR chemokine receptor binding	3/2200	50/18639	0.06	0.508336363636364	0.944715001797265	0.999999999999861
GO:0016597	amino acid binding	3/2200	51/18639	0.0588235294117647	0.498368983957219	0.949558772120872	0.999999999999861
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/2200	24/18639	0.0416666666666667	0.353011363636364	0.951021499443776	0.999999999999861
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/2200	24/18639	0.0416666666666667	0.353011363636364	0.951021499443776	0.999999999999861
GO:0004806	triacylglycerol lipase activity	1/2200	24/18639	0.0416666666666667	0.353011363636364	0.951021499443776	0.999999999999861
GO:0015295	solute:proton symporter activity	1/2200	24/18639	0.0416666666666667	0.353011363636364	0.951021499443776	0.999999999999861
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/2200	24/18639	0.0416666666666667	0.353011363636364	0.951021499443776	0.999999999999861
GO:0019957	C-C chemokine binding	1/2200	24/18639	0.0416666666666667	0.353011363636364	0.951021499443776	0.999999999999861
GO:0042626	ATPase-coupled transmembrane transporter activity	7/2200	98/18639	0.0714285714285714	0.605162337662338	0.952656256799935	0.999999999999861
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/2200	52/18639	0.0576923076923077	0.488784965034965	0.954004372539056	0.999999999999861
GO:0001848	complement binding	1/2200	25/18639	0.04	0.338890909090909	0.956809987288186	0.999999999999861
GO:0015645	fatty acid ligase activity	1/2200	25/18639	0.04	0.338890909090909	0.956809987288186	0.999999999999861
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/2200	25/18639	0.04	0.338890909090909	0.956809987288186	0.999999999999861
GO:0120515	fatty acid-CoA ligase activity	1/2200	25/18639	0.04	0.338890909090909	0.956809987288186	0.999999999999861
GO:0022804	active transmembrane transporter activity	43/2200	457/18639	0.0940919037199125	0.797172269743386	0.956925821440193	0.999999999999861
GO:0015144	carbohydrate transmembrane transporter activity	2/2200	40/18639	0.05	0.423613636363636	0.958357936775868	0.999999999999861
GO:0071855	neuropeptide receptor binding	2/2200	40/18639	0.05	0.423613636363636	0.958357936775868	0.999999999999861
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/2200	26/18639	0.0384615384615385	0.325856643356643	0.961914641202766	0.999999999999861
GO:0005227	calcium-activated cation channel activity	1/2200	26/18639	0.0384615384615385	0.325856643356643	0.961914641202766	0.999999999999861
GO:0008143	poly(A) binding	1/2200	26/18639	0.0384615384615385	0.325856643356643	0.961914641202766	0.999999999999861
GO:0008227	G protein-coupled amine receptor activity	2/2200	41/18639	0.0487804878048781	0.413281596452328	0.962507955418276	0.999999999999861
GO:0140828	metal cation:monoatomic cation antiporter activity	2/2200	41/18639	0.0487804878048781	0.413281596452328	0.962507955418276	0.999999999999861
GO:0001664	G protein-coupled receptor binding	26/2200	297/18639	0.0875420875420875	0.74168044077135	0.962860628009653	0.999999999999861
GO:0035198	miRNA binding	2/2200	42/18639	0.0476190476190476	0.403441558441558	0.966258993883643	0.999999999999861
GO:0005104	fibroblast growth factor receptor binding	1/2200	27/18639	0.037037037037037	0.313787878787879	0.966416214799387	0.999999999999861
GO:0008266	poly(U) RNA binding	1/2200	27/18639	0.037037037037037	0.313787878787879	0.966416214799387	0.999999999999861
GO:0008395	steroid hydroxylase activity	1/2200	27/18639	0.037037037037037	0.313787878787879	0.966416214799387	0.999999999999861
GO:0016829	lyase activity	16/2200	200/18639	0.08	0.677781818181818	0.968558306173295	0.999999999999861
GO:0005245	voltage-gated calcium channel activity	2/2200	43/18639	0.0465116279069767	0.394059196617336	0.969647368551113	0.999999999999861
GO:0005242	inward rectifier potassium channel activity	1/2200	28/18639	0.0357142857142857	0.302581168831169	0.970385929362108	0.999999999999861
GO:0008028	monocarboxylic acid transmembrane transporter activity	4/2200	70/18639	0.0571428571428571	0.48412987012987	0.972125117832992	0.999999999999861
GO:0003785	actin monomer binding	1/2200	29/18639	0.0344827586206897	0.292147335423197	0.973886598611657	0.999999999999861
GO:0004181	metallocarboxypeptidase activity	1/2200	29/18639	0.0344827586206897	0.292147335423197	0.973886598611657	0.999999999999861
GO:0035250	UDP-galactosyltransferase activity	1/2200	29/18639	0.0344827586206897	0.292147335423197	0.973886598611657	0.999999999999861
GO:0005254	chloride channel activity	5/2200	83/18639	0.0602409638554217	0.510377875136911	0.974032071311171	0.999999999999861
GO:0008009	chemokine activity	2/2200	45/18639	0.0444444444444444	0.376545454545455	0.975466546588792	0.999999999999861
GO:0042379	chemokine receptor binding	4/2200	72/18639	0.0555555555555556	0.470681818181818	0.976626905271356	0.999999999999861
GO:0008187	poly-pyrimidine tract binding	1/2200	30/18639	0.0333333333333333	0.282409090909091	0.976973620806947	0.999999999999861
GO:0022839	monoatomic ion-gated channel activity	1/2200	30/18639	0.0333333333333333	0.282409090909091	0.976973620806947	0.999999999999861
GO:0098918	structural constituent of synapse	1/2200	30/18639	0.0333333333333333	0.282409090909091	0.976973620806947	0.999999999999861
GO:0004180	carboxypeptidase activity	2/2200	46/18639	0.0434782608695652	0.368359683794466	0.977955743716045	0.999999999999861
GO:0005452	solute:inorganic anion antiporter activity	1/2200	31/18639	0.032258064516129	0.273299120234604	0.979695853824558	0.999999999999861
GO:0008528	G protein-coupled peptide receptor activity	8/2200	122/18639	0.0655737704918033	0.555558867362146	0.980960198925154	0.999999999999861
GO:0008378	galactosyltransferase activity	1/2200	32/18639	0.03125	0.264758522727273	0.98209638701383	0.999999999999861
GO:0070717	poly-purine tract binding	1/2200	32/18639	0.03125	0.264758522727273	0.98209638701383	0.999999999999861
GO:0015179	L-amino acid transmembrane transporter activity	3/2200	62/18639	0.0483870967741935	0.409948680351906	0.98221869925408	0.999999999999861
GO:0035254	glutamate receptor binding	2/2200	49/18639	0.0408163265306122	0.345807050092764	0.984041304201142	0.999999999999861
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/2200	34/18639	0.0294117647058824	0.24918449197861	0.986079873165433	0.999999999999861
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/2200	34/18639	0.0294117647058824	0.24918449197861	0.986079873165433	0.999999999999861
GO:0001653	peptide receptor activity	8/2200	128/18639	0.0625	0.529517045454545	0.987757750650522	0.999999999999861
GO:0015101	organic cation transmembrane transporter activity	4/2200	81/18639	0.0493827160493827	0.418383838383838	0.989647503127067	0.999999999999861
GO:0030280	structural constituent of skin epidermis	1/2200	37/18639	0.027027027027027	0.228980343980344	0.990457251428158	0.999999999999861
GO:0008514	organic anion transmembrane transporter activity	20/2200	269/18639	0.0743494423791822	0.62990875295708	0.993084131554915	0.999999999999861
GO:0140662	ATP-dependent protein folding chaperone	1/2200	40/18639	0.025	0.211806818181818	0.993458526466707	0.999999999999861
GO:0015175	neutral L-amino acid transmembrane transporter activity	1/2200	41/18639	0.024390243902439	0.206640798226164	0.994232290742918	0.999999999999861
GO:0003730	mRNA 3'-UTR binding	19/2200	262/18639	0.0725190839694656	0.614401457321305	0.994420621256698	0.999999999999861
GO:0019894	kinesin binding	1/2200	42/18639	0.0238095238095238	0.201720779220779	0.994914566276071	0.999999999999861
GO:0005253	monoatomic anion channel activity	5/2200	103/18639	0.0485436893203883	0.411275375110327	0.995384617561371	0.999999999999861
GO:0005179	hormone activity	7/2200	132/18639	0.053030303030303	0.449287190082645	0.996564122573759	0.999999999999861
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/2200	46/18639	0.0217391304347826	0.184179841897233	0.996926768903863	0.999999999999861
GO:0015108	chloride transmembrane transporter activity	6/2200	121/18639	0.0495867768595041	0.420112697220135	0.997031895928277	0.999999999999861
GO:0015085	calcium ion transmembrane transporter activity	8/2200	147/18639	0.054421768707483	0.461076066790352	0.997218255826987	0.999999999999861
GO:0099095	ligand-gated monoatomic anion channel activity	1/2200	47/18639	0.0212765957446809	0.180261121856867	0.997290406208843	0.999999999999861
GO:0015291	secondary active transmembrane transporter activity	20/2200	287/18639	0.0696864111498258	0.590402280646183	0.997629685708568	0.999999999999861
GO:0003823	antigen binding	10/2200	174/18639	0.0574712643678161	0.486912225705329	0.997746257727857	0.999999999999861
GO:0005249	voltage-gated potassium channel activity	4/2200	98/18639	0.0408163265306122	0.345807050092764	0.997947278359574	0.999999999999861
GO:0046943	carboxylic acid transmembrane transporter activity	11/2200	188/18639	0.0585106382978723	0.495718085106383	0.998071515011534	0.999999999999861
GO:0005342	organic acid transmembrane transporter activity	11/2200	189/18639	0.0582010582010582	0.493095238095238	0.998211301837742	0.999999999999861
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	3/2200	86/18639	0.0348837209302326	0.295544397463002	0.998439158303087	0.999999999999861
GO:0015171	amino acid transmembrane transporter activity	4/2200	102/18639	0.0392156862745098	0.332245989304813	0.998614562019819	0.999999999999861
GO:0008146	sulfotransferase activity	1/2200	53/18639	0.0188679245283019	0.159854202401372	0.998727399292201	0.999999999999861
GO:0005262	calcium channel activity	6/2200	131/18639	0.0458015267175573	0.388043025676613	0.998778728983615	0.999999999999861
GO:0004497	monooxygenase activity	4/2200	106/18639	0.0377358490566038	0.319708404802744	0.999068716331714	0.999999999999861
GO:0022843	voltage-gated monoatomic cation channel activity	6/2200	143/18639	0.041958041958042	0.355479974570884	0.999593503986831	0.999999999999861
GO:0022832	voltage-gated channel activity	8/2200	175/18639	0.0457142857142857	0.387303896103896	0.999740168648818	0.999999999999861
GO:0008509	monoatomic anion transmembrane transporter activity	6/2200	149/18639	0.0402684563758389	0.341165344722392	0.999768386242822	0.999999999999861
GO:0099094	ligand-gated monoatomic cation channel activity	5/2200	136/18639	0.0367647058823529	0.311480614973262	0.999796509079379	0.999999999999861
GO:0005267	potassium channel activity	4/2200	124/18639	0.032258064516129	0.273299120234604	0.99985077033804	0.999999999999861
GO:0005244	voltage-gated monoatomic ion channel activity	7/2200	173/18639	0.0404624277456647	0.342808723068839	0.999909195330002	0.999999999999861
GO:0015081	sodium ion transmembrane transporter activity	6/2200	164/18639	0.0365853658536585	0.309961197339246	0.99994501854252	0.999999999999861
GO:0015103	inorganic anion transmembrane transporter activity	6/2200	165/18639	0.0363636363636364	0.308082644628099	0.999950119019572	0.999999999999861
GO:0015370	solute:sodium symporter activity	1/2200	79/18639	0.0126582278481013	0.107243958573072	0.999952011848558	0.999999999999861
GO:0015293	symporter activity	4/2200	146/18639	0.0273972602739726	0.232117061021171	0.999985279086803	0.999999999999861
GO:0015294	solute:monoatomic cation symporter activity	2/2200	116/18639	0.0172413793103448	0.146073667711599	0.999992542140788	0.999999999999861
GO:0015276	ligand-gated monoatomic ion channel activity	6/2200	186/18639	0.032258064516129	0.273299120234604	0.999993780920655	0.999999999999861
GO:0022834	ligand-gated channel activity	6/2200	188/18639	0.0319148936170213	0.2703916827853	0.999994917058859	0.999999999999861
GO:0005261	monoatomic cation channel activity	17/2200	341/18639	0.0498533724340176	0.422371367635297	0.999996069531902	0.999999999999861
GO:0015079	potassium ion transmembrane transporter activity	4/2200	160/18639	0.025	0.211806818181818	0.999996745127243	0.999999999999861
GO:0005216	monoatomic ion channel activity	22/2200	448/18639	0.0491071428571429	0.416049107142857	0.999999886159297	0.999999999999861
GO:0046873	metal ion transmembrane transporter activity	22/2200	450/18639	0.0488888888888889	0.4142	0.999999903182656	0.999999999999861
GO:0022836	gated channel activity	10/2200	318/18639	0.0314465408805031	0.266423670668954	0.999999994808525	0.999999999999861
GO:0045182	translation regulator activity	12/2200	356/18639	0.0337078651685393	0.285582226762002	0.999999997631561	0.999999999999861
GO:0030371	translation repressor activity	5/2200	329/18639	0.0151975683890578	0.128757944183476	0.999999999999861	0.999999999999861